Proteomics News and Research

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The term 'proteome' was first coined in 1994, and refers to all the proteins in a cell, tissue, or organism. Proteomics refers to the study of the proteome. Because proteins are involved in almost all biological activities, the proteome is a rich source of biological information.

Scientists sheds light on small protein and its role in immune response

The immune system is the body’s defense against disease-causing pathogens. It works by warding off disease and potentially-damaging foreign bodies. Now, a team of researchers have developed a new method to shed light on the basic defense mechanism of the immune system.

27 Nov 2019

Over €12 million funding to advance autophagy research

Four years ago, Collaborative Research Centre (CRC) 1177 on selective autophagy was established under the leadership of Goethe University - now the German Research Foundation has given the green light for its further funding.

27 Nov 2019

Accelerating Medicines Partnership program for Parkinson’s disease launches new data portal

The Accelerating Medicines Partnership program for Parkinson's disease (PD) has launched a data portal to provide de-identified information collected from 4,298 PD patients and healthy controls to researchers working to develop effective therapies for the disease.

22 Nov 2019

Doughnut-shaped circles of ecDNA provide tumor cells with a malignant twist

Deoxyribonucleic acid or DNA encodes information, not only in its sequence but also in its shape.

21 Nov 2019

Researchers discover a peptide involved in both migraine and opioid-overuse pain

About 10% of the world population suffers from migraine headaches, according to the National Institute of Neurological Disorders and Stroke.

20 Nov 2019

Applying a Proteomics-based Approach to the Clinic

Matthias Mann explains why applying proteomics-based technologies such as timsTOF could accelerate the diagnosis and prediction of human disease.

From Bruker Daltonics 20 Nov 2019

Proteomics & DIA Mass Spectrometry in Neurodegenerative Disease Research

News-Medical Life Sciences spoke to Nicholas Dupuis from Biognosys about proteomics & DIA mass spectrometry in neurodegenerative disease research.

From Biognosys 19 Nov 2019

CSU awarded $1.2 million subcontract to accelerate tuberculosis vaccine development

A team of researchers in the Department of Microbiology, Immunology and Pathology at Colorado State University aim to advance what is known about the complex immune response necessary to prevent tuberculosis disease.

15 Nov 2019

UAB study suggests potential treatment target for IPF

Long-held dogma says lung fibrosis in diseases like idiopathic pulmonary fibrosis, or IPF, results from recurrent injury to alveolar epithelium that is followed by dysregulated repair.

12 Nov 2019

New method for identifying 'biomarkers' of drug response in triple-negative breast cancer cell lines

Triple-negative breast cancer is an aggressive cancer, one that's likely to recur and to metastasize.

10 Nov 2019

Study shows how glucocorticoid hormones control sugar and fat levels over the course of 24 hours

For the first time, a study led by researchers at Helmholtz Zentrum München and the German Center for Diabetes Research shows how glucocorticoid hormones, such as cortisol, control sugar and fat levels differently during day and night, feeding and fasting, rest and activity, over the course of 24 hours.

10 Nov 2019

Humanizing cell cultures

Today we know the function and metabolism of any mammalian cell depends on its environment. Such cells have long been cultured under conditions consisting of a basal medium with added nutritional serum. This, however, is not an accurate replica of the cell’s environment within the human body.

5 Nov 2019

How venom from marine cone snails can be used in pain therapy

Conotoxins are bioactive peptides found in the venom that marine cone snails produce for prey capture and defense.

4 Nov 2019

Risky strategy allows malaria parasite to quickly respond to unpredictable changes

The parasite that causes malaria expresses genes that code for the proteins it will need in later life stages, using two separate schemes to prevent these proteins from actually being made until they are needed, according to new research.

31 Oct 2019

Researchers identify new kidney cancer subtypes and clues to better diagnosis, treatment

In what is believed to be the most comprehensive molecular characterization to date of the most common - and often treatment-resistant - form of kidney cancer, researchers at Johns Hopkins' departments of pathology and oncology, Johns Hopkins Kimmel Cancer Center, and the Johns Hopkins University School of Medicine report evidence for at least three distinct subtypes of clear cell renal cell carcinoma (ccRCC), along with new revelations about the proteins that define them.

From Johns Hopkins Medicine 31 Oct 2019

CEM enters into a definitive agreement to purchase key assets of Intavis Bioanalytical Instruments

CEM Corporation today announced that it has entered into a definitive agreement to purchase the instrumentation lines of Intavis Bioanalytical Instruments AG, with headquarters in Cologne Germany. The acquisition allows CEM to strengthen its product offering in the Life Sciences for proteomics, in-situ hybridization and particularly in the field of peptide synthesis.

From CEM Corporation - Life Science 30 Oct 2019

New protein painting technology could transform drug discovery process

George Mason University researchers have discovered the exact location where two proteins responsible for hiding cancer cells from the immune system bind.

8 Oct 2019

HIV-1 Tat expression leads to perturbations in cellular protein expression, research suggests

The cover for issue 54 of Oncotarget features Figure 2, "Comparative proteomic profiling of the peptides/proteins identified from 293T, IL16lamp2b and mExo-Tat samples," by Lu, et al.

4 Oct 2019

Rapid Novor moves into a new state-of-the-art facility for next phase of growth

Rapid Novor, Inc., the world's leader in antibody protein sequencing using mass spectrometry, is pleased to announce that it has moved into a new, 5000 sqft, purpose-built, state-of-the-art facility.

From Rapid Novor Inc 4 Oct 2019

Researchers observe the effects of two proteins responsible for metastasis

The research by Assoc. Prof. Nurhan özlü of Koç University Department of Molecular Biology and Genetics and her team recently published in Molecular & Cellular Proteomics has observed the effects of two proteins in the transition from the epithelial to the mesenchymal cell type, the latter of which has mobility.

2 Oct 2019

Proteomics News and Research

Further Reading

Scientists sheds light on small protein and its role in immune response

Over €12 million funding to advance autophagy research

Accelerating Medicines Partnership program for Parkinson’s disease launches new data portal

Doughnut-shaped circles of ecDNA provide tumor cells with a malignant twist

Researchers discover a peptide involved in both migraine and opioid-overuse pain

Applying a Proteomics-based Approach to the Clinic

Proteomics & DIA Mass Spectrometry in Neurodegenerative Disease Research

CSU awarded $1.2 million subcontract to accelerate tuberculosis vaccine development

UAB study suggests potential treatment target for IPF

New method for identifying 'biomarkers' of drug response in triple-negative breast cancer cell lines

Study shows how glucocorticoid hormones control sugar and fat levels over the course of 24 hours

Humanizing cell cultures

How venom from marine cone snails can be used in pain therapy

Risky strategy allows malaria parasite to quickly respond to unpredictable changes

Researchers identify new kidney cancer subtypes and clues to better diagnosis, treatment

CEM enters into a definitive agreement to purchase key assets of Intavis Bioanalytical Instruments

New protein painting technology could transform drug discovery process

HIV-1 Tat expression leads to perturbations in cellular protein expression, research suggests

Rapid Novor moves into a new state-of-the-art facility for next phase of growth

Researchers observe the effects of two proteins responsible for metastasis

Industry Focus eBook - Protein Analysis (3rd edition) eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo