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Cell’s production of lipids can be a key factor in determining cell fate

How does a cell "decide" what type of cell to become? The question of "cell fate" has been explored for decades now, especially in the context of stem cell biology, but there are still gaps in our understanding.

15 Apr 2022

The molecular context and substrate profiles of human cell surface receptor tyrosine kinases

researchers discussed and identified the systemic functions and interactions of 52 active cell surface receptor tyrosine kinases, providing insights on RTK-RTK interactions and substrates, RTK-protein complexes, and signaling pathways.

13 Apr 2022

Researchers make progress to develop a drug for treating metabolic syndrome

Metabolic syndrome increases a person's risk for diabetes, heart disease, and stroke, and includes conditions such as obesity, high blood pressure and high blood sugar.

11 Apr 2022

Exploring evolutionary trajectories of SARS-CoV-2 interacting proteins in bats and primates

Researchers performed high-throughput evolutionary analyses of genes encoding 334 SARS-CoV-2 viral-interacting proteins of modern humans, primates, and bats.

11 Apr 2022

Ultralong bovine antibody targets cryptic and conserved epitope on SARS-CoV and SARS-CoV-2

Researchers identified an ultralong bovine antibody that neutralizes SARS-CoV-2 and SARS-CoV.

11 Apr 2022

S-Nitrosylation of ACE2 inhibits binding of SARS-CoV-2 spike protein

In a recent study posted to the bioRxiv* preprint server, researchers developed aminoadamantane nitrates compounds that inhibit the ion channels formed by the envelope (E) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and enable targeted drug delivery of nitric oxide (NO)-related group for S-nitrosylation of host angiotensin-converting enzyme 2 (ACE2), which would inhibit ACE2 binding with the viral spike (S) protein and thereby inhibit viral replication in the host.

11 Apr 2022

COVID-19 could change the levels of proteins related to male reproductive function

Many people who recover from COVID-19 experience long-term symptoms, such as brain fog or heart problems. Increasing evidence suggests that the virus can also impair fertility.

7 Apr 2022

Molecular signature of highly stereotyped clonotypic anti-PF4 antibodies indicates shared pathways of antibody production in VITT patients

A recent study analyzed the antibody that mediated the COVID-19 vaccine-induced thrombotic thrombocytopenia.

7 Apr 2022

UCI researchers reveal the impact of native lipids on rhodopsin signaling and regeneration

In a new study at University of California, Irvine, researchers have revealed the impact of native lipids on rhodopsin signaling and regeneration, which may usher in a new paradigm for discovery of drugs that target G protein-coupled receptors (GPCRs).

6 Apr 2022

Researchers develop novel device to “cleanse” the blood of chemotherapeutic drugs

For patients with cancer, the tumor-killing power of chemotherapeutic drugs is a double-edged sword. While many cancer drugs kill tumor cells, they can also harm healthy cells as they travel throughout the bloodstream.

6 Apr 2022

Study highlights immune escape mutations in viral N-terminal domain supersite of SARS-CoV-2 spike variants

Researchers characterized SARS-CoV-2 spike (S) isolates extracted from the samples of two individuals infected with the virus in Peru (ΔN25) and Brazil (ΔN135) in January 2021.

6 Apr 2022

Gut bacterium may be an important factor in resistance to antihypertensive medications

Almost half of the U.S. adult population has high blood pressure - or hypertension - and about 20% of these patients have treatment-resistant hypertension.

5 Apr 2022

Researchers use breast milk to identify new set of protein biomarkers for cancer

A simple blood test for women of all ages and risk levels could one day be possible thanks to a new set of protein biomarkers that researchers identified using breast milk.

4 Apr 2022

A summary of SARS-CoV-2 RNA-protein interactome studies

A new study summarized the importance of SARS-CoV-2 ribonucleic acid protein interactomes in the study of RNA viruses.

30 Mar 2022

IgG Fc glycosylation: A marker for severe COVID-19

Researchers suggest that low anti-spike IgG1 glycosylation, sialyation, and high bisection are markers of severe COVID-19.

24 Mar 2022

New approach could lead to quicker generation of effective, personalized cancer vaccines

Scientists have created a pipeline for identifying, prioritizing and evaluating potential tumor antigens for the fast generation of cancer vaccines, according to a report published today in eLife.

22 Mar 2022

Influence of vitamin D and age on first SARS-CoV-2 vaccine dose efficacy

Researchers illustrated that vitamin D status and age influence antibody response following the initial dose of coronavirus disease 2019 vaccination.

21 Mar 2022

Antimicrobial resistance in COVID-19

Researchers discuss the impact of this extensive use of antibiotics on the rise of antimicrobial resistance.

16 Mar 2022

Acacetin shows potency against SARS-CoV-2 spike protein

Researchers use molecular docking to screen phytocompounds and evaluate their binding affinity with SARS-CoV-2.

15 Mar 2022

Detailed molecular map of stratum corneum can help develop new skin treatments

Scientists have accurately analyzed the tough barrier layer of the skin giving the most detailed molecular map of its structure that will help in the development of new skin products and treatments.

14 Mar 2022

Spectrometry News and Research

Cell’s production of lipids can be a key factor in determining cell fate

The molecular context and substrate profiles of human cell surface receptor tyrosine kinases

Researchers make progress to develop a drug for treating metabolic syndrome

Exploring evolutionary trajectories of SARS-CoV-2 interacting proteins in bats and primates

Ultralong bovine antibody targets cryptic and conserved epitope on SARS-CoV and SARS-CoV-2

S-Nitrosylation of ACE2 inhibits binding of SARS-CoV-2 spike protein

COVID-19 could change the levels of proteins related to male reproductive function

Molecular signature of highly stereotyped clonotypic anti-PF4 antibodies indicates shared pathways of antibody production in VITT patients

UCI researchers reveal the impact of native lipids on rhodopsin signaling and regeneration

Researchers develop novel device to “cleanse” the blood of chemotherapeutic drugs

Study highlights immune escape mutations in viral N-terminal domain supersite of SARS-CoV-2 spike variants

Gut bacterium may be an important factor in resistance to antihypertensive medications

Researchers use breast milk to identify new set of protein biomarkers for cancer

A summary of SARS-CoV-2 RNA-protein interactome studies

IgG Fc glycosylation: A marker for severe COVID-19

New approach could lead to quicker generation of effective, personalized cancer vaccines

Influence of vitamin D and age on first SARS-CoV-2 vaccine dose efficacy

Antimicrobial resistance in COVID-19

Acacetin shows potency against SARS-CoV-2 spike protein

Detailed molecular map of stratum corneum can help develop new skin treatments

Enhancing confidence in chemical ionization spectrometry data eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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