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Treating desmoplastic melanoma with immunotherapy before surgery can shrink or eliminate tumors

New results from a clinical trial co-led by UCLA investigators demonstrate how treating desmoplastic melanoma, a rare and aggressive skin cancer, with immunotherapy before surgery can dramatically shrink or even eliminate tumors, sparing patients from more aggressive surgeries and preserving their quality of life.

29 Jan 2026

Soluble E-cadherin drives brain metastasis in aggressive inflammatory breast cancer

Researchers at The University of Texas MD Anderson Cancer Center have identified a targetable driver of brain metastases in patients with aggressive inflammatory breast cancer.

28 Jan 2026

New nanomaterial kills cancer cells via oxidative stress

Scientists at Oregon State University have developed a new nanomaterial that triggers a pair of chemical reactions inside cancer cells, killing the cells via oxidative stress while leaving healthy tissues alone.

28 Jan 2026

Four-biomarker blood panel enhances the detection of pancreatic ductal adenocarcinoma

A four-biomarker blood panel of aminopeptidase N (ANPEP), polymeric immunoglobulin receptor (PIGR), CA19-9, and thrombospondin-2 (THBS2) enhanced the detection of pancreatic ductal adenocarcinoma (PDAC) compared to measuring CA19-9 levels alone.

28 Jan 2026

Clinical trial aims to improve survival for patients with recurrent head and neck cancer

A newly approved National Cancer Institute-funded clinical trial aims to improve survival for head and neck cancer patients whose disease returns after radiation therapy – a setback that affects up to 40% of patients and is often associated with poor outcomes.

27 Jan 2026

Antibody-producing plasma cells shape effectiveness of PD-1 immunotherapy

Scientists at the Icahn School of Medicine at Mount Sinai have identified an important immune response that helps explain why some cancer patients benefit from immunotherapy while others do not.

27 Jan 2026

Brain organoids reveal glioblastoma's secrets and therapy resistance

UCLA scientists have developed advanced miniature 3D tumor organoid models that make it possible to study glioblastoma tumors in a setting that closely mirrors the human brain, shedding light on how the aggressive cancer interacts with surrounding brain cells and the immune system to become more invasive and resistant to therapy.

27 Jan 2026

Vortex Biotech opens new state-of-the-art laboratory at Manchester Science Park

Vortex Biotech Holdings Limited has announced the opening of its advanced laboratory facilities at Manchester Science Park.

27 Jan 2026

JPM highlights | WuXi Biologics CEO Dr. Chris Chen: Scaled CRDMO platform delivering sustainable high growth

JPM Highlights | WuXi Biologics CEO Dr. Chris Chen: Scaled CRDMO Platform Delivering Sustainable High Growth

From WuXi Biologics 27 Jan 2026

New prognostic model improves survival prediction for spinal metastasis patients

Spinal metastasis, the spread of cancer to the spine, is a frequent complication in advanced cancer. It often causes severe pain and paralysis, significantly impacting quality of life.

27 Jan 2026

New 2026 guideline expands access to advanced acute ischemic stroke care

Expanded eligibility for advanced stroke therapies and new recommendations for diagnosing and treating stroke in children and adults are among the major updates in the new 2026 Guideline for the Early Management of Patients With Acute Ischemic Stroke from the American Stroke Association, a division of the American Heart Association, published today in the Association's flagship journal Stroke.

26 Jan 2026

Physical behavior reveals aggressive cancer cells in a simple new approach

New study shows that aggressive cancer cells can be identified in a simple, new way; by how they physically behave, not just by their genes.

26 Jan 2026

Diagnostic prognostic and therapeutic relevance of PIVKA-II in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality worldwide, particularly in regions with high hepatitis B virus prevalence.

24 Jan 2026

Orphan noncoding RNAs define cancer identity and enable blood-based monitoring

We knew we had something interesting with T3p, a single small RNA found in breast cancer but absent from normal tissue.

24 Jan 2026

Metabolic reprogramming drives prostate cancer progression and treatment resistance

Prostate cancer (PCa) is one of the most common malignant tumors among men worldwide. Following androgen deprivation therapy (ADT), the disease often progresses to castration-resistant prostate cancer (CRPC).

24 Jan 2026

Dual-responsive nanodelivery system enhances immunotherapy efficacy in metastatic bladder cancer

Metastatic urothelial carcinoma has a poor prognosis: ~50% of muscle-invasive bladder cancer progresses to metastasis, and the 5-year survival for advanced/metastatic disease is <10%.

24 Jan 2026

Cigarette compound exposure drives sorafenib resistance in hepatocellular carcinoma

A research team led by Professor Yuan Li at Nanjing Medical University published a research paper entitled "A Cigarette Compound-Induced Tumor Microenvironment Promotes Sorafenib Resistance in Hepatocellular Carcinoma via the 14-3-3η-Modified Tumor-Associated Proteome" in the Chinese Medical Journal.

23 Jan 2026

Trojan horse immunotherapy opens tumors to immune system attack

Scientists at the Icahn School of Medicine at Mount Sinai have developed an experimental immunotherapy that takes an unconventional approach to metastatic cancer: instead of going after cancer cells directly, it targets the cells that protect them.

22 Jan 2026

Cancer vaccines enter a new era of personalized immunotherapy

A new comprehensive review from researchers at the Icahn School of Medicine at Mount Sinai details how decades of cancer vaccine research are converging into a new era of more precise, personalized, and effective immunotherapies, particularly when combined with other cancer treatments.

22 Jan 2026

Pre-surgical medication use grows for pancreatic, gynecologic, and abdominal lining cancers

The second annual report from the National Cancer Database (NCDB) of the American College of Surgeons (ACS) documents a substantial rise in medication treatments, such as chemotherapy, immunotherapy, and hormone therapy, used before surgery to treat many cancers, often allowing less invasive surgery and helping clinicians assess how a patient's cancer responds to medication to guide the most effective treatment options.

22 Jan 2026

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Tumor News and Research

Treating desmoplastic melanoma with immunotherapy before surgery can shrink or eliminate tumors

Soluble E-cadherin drives brain metastasis in aggressive inflammatory breast cancer

New nanomaterial kills cancer cells via oxidative stress

Four-biomarker blood panel enhances the detection of pancreatic ductal adenocarcinoma

Clinical trial aims to improve survival for patients with recurrent head and neck cancer

Antibody-producing plasma cells shape effectiveness of PD-1 immunotherapy

Brain organoids reveal glioblastoma's secrets and therapy resistance

Vortex Biotech opens new state-of-the-art laboratory at Manchester Science Park

JPM highlights | WuXi Biologics CEO Dr. Chris Chen: Scaled CRDMO platform delivering sustainable high growth

New prognostic model improves survival prediction for spinal metastasis patients

New 2026 guideline expands access to advanced acute ischemic stroke care

Physical behavior reveals aggressive cancer cells in a simple new approach

Diagnostic prognostic and therapeutic relevance of PIVKA-II in hepatocellular carcinoma

Orphan noncoding RNAs define cancer identity and enable blood-based monitoring

Metabolic reprogramming drives prostate cancer progression and treatment resistance

Dual-responsive nanodelivery system enhances immunotherapy efficacy in metastatic bladder cancer

Cigarette compound exposure drives sorafenib resistance in hepatocellular carcinoma

Trojan horse immunotherapy opens tumors to immune system attack

Cancer vaccines enter a new era of personalized immunotherapy

Pre-surgical medication use grows for pancreatic, gynecologic, and abdominal lining cancers

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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