Tumor News and Research

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New model developed to optimize and personalize radiotherapy for cancer patients

A personalized approach to cancer treatment has become more common over the last several decades, with numerous targeted drugs approved to treat particular tumor types with specific mutations or patterns.

22 Aug 2019

Enzyme induced by stress associated with liver cancer growth

An enzyme induced by stress to help reduce production of damaging free radicals is also used by liver cancer to regulate two major cell proliferation pathways that enable the cancer to thrive, scientists report.

22 Aug 2019

'Kissing loops' in lncRNA essential for tumor suppressor function

Human cells - like those of many other organisms - have developed mechanisms to protect us from cancer.

22 Aug 2019

UC San Diego researchers identify new therapeutic approach to kill cancer cells

Epithelial cancers, such as cancers of the lung and pancreas, use the ανβ3 molecule to gain drug resistance to standard cancer therapies and to become highly metastatic.

22 Aug 2019

Study opens up a new way for developing potential glioblastoma treatment

A team led by Texas A&M University's College of Veterinary Medicine & Biomedical Sciences' researcher Dr. Stephen Safe has discovered a new pathway that may help suppress the development of glioblastoma tumors, one of the deadliest forms of cancer.

22 Aug 2019

New cannabis-based drug shows promise for pancreatic cancer

Cancer of the pancreas is a particularly deadly cancer, claiming over 90% of its victims within 5 years from diagnosis. It resists most standard therapies, including surgery, chemotherapy, radiation therapy, immunotherapy and targeted therapy, and metastasizes early, often before being diagnosed. A cure is possible only with very localized tumors.

22 Aug 2019

Research explains why many psychiatric drugs that work in the lab don’t work in people

Current drug development for neuropsychiatric disorders is in crisis, say experts. More than 90 percent of all drugs that are developed for illnesses like schizophrenia, depression, Alzheimer’s disease (AD), or the brain tumor glioblastoma complete successful trials in mice but then come to a grinding halt in human trials, wasting billions of dollars in drug research. This is partly because of obvious behavioral differences between the two species.

22 Aug 2019

International study identifies new drug target for treating glioblastoma

A new international study co-led by Cleveland Clinic has identified a new drug target for treating glioblastoma. This target is part of a never-before defined cellular pathway found to contribute to the spread and proliferation of a dangerous subset of cancer cells, called glioma stem cells.

22 Aug 2019

FDA clears its IND for new immunotherapeutic for treating prostate cancer

Calibr, the drug development division of Scripps Research, announced today that the U.S. Food and Drug Administration has cleared its investigational new drug application for CCW702, a novel immunotherapeutic for the treatment of patients with metastatic castration-resistant prostate cancer.

21 Aug 2019

Drug that treat human breast cancer might also work for canine lung cancer

Despite those velvet paintings of poker-playing dogs smoking pipes, cigars and cigarettes, our canine friends really don't use tobacco. But like many humans who have never smoked, dogs still get lung cancer.

21 Aug 2019

New study provides a better understanding of Merkel cell carcinoma

Merkel cell carcinoma is a rare and aggressive type of skin cancer. Also called neuroendocrine carcinoma of the skin, it is much less common than most other types of skin cancer. But, it’s one of the most dangerous types since it’s more likely to spread to the other parts of the body.

21 Aug 2019

Study identifies key epigenetic regulator that controls skin cell turnover

The outer layer of the skin completely replaces itself every two to four weeks, but when this process is blocked, cancer can grow.

21 Aug 2019

New insight into the immune system may help doctors to better fight cancer

Your immune system's natural killer cells recognize and attack two major kinds of danger - cells infected by viruses and cells affected by cancer.

20 Aug 2019

Largest genomic analysis could help improve treatment for Merkel cell carcinoma patients

Merkel cell carcinoma is a rare, aggressive skin tumor that is diagnosed in approximately 2,000 people each year in the United States.

20 Aug 2019

Simple test could help diagnose glioblastoma

Scientists at the University of Sussex could be a step closer to developing the first-ever blood test to diagnose the most aggressive type of brain cancer, glioblastoma.

20 Aug 2019

FDA approves cold atmospheric plasma technology for first-ever use in clinical trial

Cold atmospheric plasma technology, currently the only way to remove microscopic cancer tumors remaining from surgery, has been approved by the U.S. Food and Drug Administration for first-ever use in a clinical trial.

20 Aug 2019

Dacomitinib treatment for lung cancer increases overall survival but has more side effects

Since its approval in April 2019, dacomitinib has been available for the first-line treatment of adult patients with locally advanced or metastatic non-small cell lung cancer with epidermal growth factor receptor activating mutations.

20 Aug 2019

Study: Blocking inflammatory pathway could prevent melanoma brain metastasis

Brain metastases are among the deadliest tumor metastases, with a median survival period of less than one year, and the incidence of brain metastasis is rising.

20 Aug 2019

Researchers develop new gene editing system that could be used for anticancer immunotherapy

Dr. Mihue Jang and her group at the Center for Theragnosis of the Korea Institute of Science and Technology announced that they have developed a new gene-editing system that could be used for anticancer immunotherapy through the simultaneous suppression of proteins that interfere with the immune system expressed on the surface of lymphoma cells and activation of cytotoxic T lymphocyte, based on the results of joint research conducted with Prof. Seokmann Hong and his group at Sejong University.

20 Aug 2019

Study uncovers potential new treatment approach for lung cancer

Lung cancer is the second most common cancer found in both men and women. It is estimated there will be roughly 228,000 new lung cancer cases this year, and nearly 30% of those patients will have mutations in the KRAS pathway.

19 Aug 2019