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Cascade of costs could push new gene therapy above $1 million per patient

Outrage over the high cost of cancer care has focused on skyrocketing drug prices, including the $475,000 price tag for the country's first gene therapy, Novartis' Kymriah, a leukemia treatment approved in August.

17 Oct 2017

Family approach can be effective strategy for managing chronic illness

Family members often play an important role in managing chronic illnesses, and a family approach may produce more effective, long-term benefits for the patient, according to a Penn State researcher.

16 Oct 2017

Einstein scientists share $9 million NIH grant for longevity research

Scientists now believe that the Fountain of Youth flows from our genes, or at least from the genes of people who live healthy lives to age 100 or later.

16 Oct 2017

Anti-hypertensive treatments do not restore microvascular function

Treatments for high blood pressure do not totally reverse its damaging effects on the vascular rhythms that help circulation of the blood say researchers.

16 Oct 2017

Researchers identify new molecular pathway that controls aging in worms

Investigators at Case Western Reserve University School of Medicine and University Hospitals Health System have identified a new molecular pathway that controls lifespan and healthspan in worms and mammals.

13 Oct 2017

TSRI scientists develop molecular model for improving design of osteoporosis treatments

Using advanced mass spectrometry technology, scientists from the Florida campus of The Scripps Research Institute have developed a molecular model that may provide a new framework for improving the design of osteoporosis treatments.

13 Oct 2017

Specific regions of silenced DNA help define cell's identity, study suggests

The fundamental mechanisms governing how cells form an identity such as becoming a muscle cell or a nerve cell are not fully understood. Multiple diseases, including cancer, have been linked to cells going down the wrong developmental path during maturation.

13 Oct 2017

Fires prey on frail residents living on their own

They were asleep when the fire reached their home. Charles Rippey, 100, and his wife, Sara, 98, had been married 75 years. They died together, after a caregiver struggled to save them but couldn't get them out in time.

13 Oct 2017

Study helps understand basic mechanisms of mitochondrial DNA maintenance

Researchers at the University of Eastern Finland have discovered a novel mechanism safeguarding mitochondrial DNA. The study, published in PNAS earlier this week, was carried out in close collaboration with research groups from CBMSO in Madrid, Spain, and Umeå University in Sweden.

13 Oct 2017

Social security giveth, medical costs taketh away

Retirees spent on average more than a third of their Social Security benefits on out-of-pocket medical costs in 2014, according to a recent study. Even after factoring in other sources of income, medical spending still took a substantial 18 percent bite out of seniors' total retirement income, the study found.

13 Oct 2017

MIT researchers develop new technique to screen for genes that protect against diseases

Using a modified version of the CRISPR genome-editing system, MIT researchers have developed a new way to screen for genes that protect against specific diseases.

12 Oct 2017

Dementia patient at center of spoon-feeding controversy dies

An Oregon woman with Alzheimer's disease, whose husband claimed she was kept alive with spoon-feeding against her written wishes, has died.

12 Oct 2017

BU researchers receive grant to explore ways of capturing health data using mobile devices

Researchers from Boston University School of Medicine are the recipients of a three-year, $446,999 grant from the Robert Wood Johnson Foundation to explore different approaches to capturing health data using mobile devices such as smartphones.

11 Oct 2017

Gut microbiota of healthy elders not different from 30 year-olds, study shows

In one of the largest microbiota studies conducted in humans, researchers at Western University, Lawson Health Research Institute and Tianyi Health Science Institute in Zhenjiang, Jiangsu, China have shown a potential link between healthy aging and a healthy gut.

11 Oct 2017

Menopause causes metabolic changes in the brain that may increase Alzheimer's risk

Menopause causes metabolic changes in the brain that may increase the risk of Alzheimer's disease, a team from Weill Cornell Medicine and the University of Arizona Health Sciences has shown in new research.

10 Oct 2017

Taking sleep medications to treat insomnia may increase risk of falling for older adults

Taking physician-recommended sleep medications to treat insomnia may actually increase the risk of falling for older adults, according to a team of sleep researchers.

10 Oct 2017

Effects of having familiar, good neighbors revealed in bird study

Birds who live next door to family members or to other birds they know well are physically healthier and age more slowly, according to new research from the University of East Anglia.

10 Oct 2017

Researchers design new tool to help GPs assess frailty in older people

Researchers have designed a new tool designed to help GPs assess which older people are the most frail and vulnerable.

10 Oct 2017

Penn’s ITMAT 12th Annual International Symposium focuses on pain biology, aging, and brain disorders

The latest science in why pain afflicts people differently, precision medicine and brain disorders, and how the bat genome informs the study of human aging, among many other topics, will be covered at the University of Pennsylvania's Institute for Translational Medicine and Therapeutics' 12th Annual International Symposium.

9 Oct 2017

Rutgers scientists find efficient way to enhance nutritional value of corn

Rutgers scientists have found an efficient way to enhance the nutritional value of corn - the world's largest commodity crop - by inserting a bacterial gene that causes it to produce a key nutrient called methionine, according to a new study.

9 Oct 2017