B Cell News and Research

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Revolution in neuroscience: 2D nanomaterials propel advances in brain repair, treatment, and diagnosis

Review discusses the increasing importance of two-dimensional nanomaterials like graphene in neuroscience, highlighting their potential in nerve repair, creating brain-mimicking synaptic devices, and treating neurological disorders. It also considers the challenges and future prospects of these materials in this complex field.

11 Jun 2023

Researchers create first integrated single-cell atlas of the human lung

The largest and most comprehensive cell map of the human lung is announced in Nature Medicine today (8 June). Revealing the great diversity of cell types in the lung and key differences between health and disease, the Human Lung Cell Atlas will be a valuable resource for lung researchers.

10 Jun 2023

Using Src N-terminal regulatory element as potential oncotarget

A new research perspective was published in Oncotarget's Volume 14 on May 19, 2023, entitled, "Targeting the Src N-terminal regulatory element in cancer."

9 Jun 2023

Scientists determine the atomic-level structure of a zinc-transporter protein

Scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have determined the atomic-level structure of a zinc-transporter protein, a molecular machine that regulates levels of this crucial trace metal micronutrient inside cells.

9 Jun 2023

Binge drinking during adolescence leads to long-lasting brain changes, research suggests

Heavy alcohol consumption may cause permanent dysregulation of neurons, or brain cells, in adolescents, according to a new study in mice.

9 Jun 2023

Innovative 'village in a dish' system can accelerate stem cell research

A powerful new stem cell technique has enabled large-scale studies of the relationship between human genetics and biology.

9 Jun 2023

Mechanistic insights into how the SARS-CoV-2 virus affects the nervous system, alters its function, and causes neuropathology

Study demonstrates that SARS-CoV-2 infection and viral fusogens cause glial and neuronal fusion.

9 Jun 2023

Investigating the alveolar type II reparative response in COVID-19 pneumonia

Researchers investigated the alveolar type II reparative response in COVID-19 pneumonia.

9 Jun 2023

SARS-CoV-2 hijacks body's metabolism to amplify COVID-19 severity

In a review article published in the journal Signal Transduction and Targeted Therapy, scientists have discussed host metabolic alteration triggered by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its effect on disease severity.

9 Jun 2023

MIS-C in children: A distinct autoimmune response to COVID-19 unveiled

The study reveals that MIS-C patients, post SARS-CoV-2 infection, develop a unique immune response against the virus' N protein, indicating a cross-reactivity with the self-protein SNX8, which might link the infection to the ensuing inflammatory syndrome.

8 Jun 2023

Scientists unlock virus-fighting power with synthetic nanobody platform

Discovery and validation of nanobodies, a promising class of biologics, for viral infection prevention and treatment, including anti-SARS-CoV-2 nanobodies with enhanced neutralization properties through synergistic pairing. The study demonstrates the potential of nanobodies in developing effective therapies against viral infections.

8 Jun 2023

Biologists discover a previously unknown way that the immune system detects viruses

Inflammasomes make up an intricate system of molecular sensors that our bodies use to sound an alarm when an infection occurs.

8 Jun 2023

Study may help advance data on oncolytic adenovirus mediated double suicide-gene therapy for high-grade brain tumors

Researchers in the Hermelin Brain Tumor Center at Henry Ford Health are leading a Phase I clinical trial studying the maximum tolerated dose of an oncolytic adenovirus, a mutated virus engineered to selectively replicate in and destroy cancer tissue, in combination with fractionated stereotactic radiosurgery among patients who are undergoing resection of a recurrent high-grade astrocytoma brain tumor.

8 Jun 2023

Cryo-EM reveals key atomic structures of the ends of actin filament

Actin filaments - protein structures critical to living movement from single cells to animals - have long been known to have polarity associated with their physical characteristics, with growing "barbed" and shrinking "pointed" ends.

8 Jun 2023

Insilico Medicine nominates pan-TEAD inhibitor as a potential solution for drug resistance in solid tumor patients

Insilico Medicine, a generative artificial intelligence (AI)-driven clinical-stage drug discovery company, today announced the nomination of ISM6331, a potential best-in-class pan-TEAD inhibitor, as a preclinical candidate compound (PCC) generated by Chemistry42, its proprietary generative chemistry-driven molecule design engine, targeting the Hippo pathway for the treatment of advanced solid tumors.

8 Jun 2023

Study uncovers novel mechanisms underlying plant immunity against major root disease

Researchers led by CHEN Yuhang and ZHOU Jianmin from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences have shown how plants resist clubroot, a major root disease that threatens the productivity of Brassica crops such as rape.

8 Jun 2023

B Cell News and Research

Revolution in neuroscience: 2D nanomaterials propel advances in brain repair, treatment, and diagnosis

Researchers create first integrated single-cell atlas of the human lung

Using Src N-terminal regulatory element as potential oncotarget

Scientists determine the atomic-level structure of a zinc-transporter protein

Binge drinking during adolescence leads to long-lasting brain changes, research suggests

Innovative 'village in a dish' system can accelerate stem cell research

Mechanistic insights into how the SARS-CoV-2 virus affects the nervous system, alters its function, and causes neuropathology

Investigating the alveolar type II reparative response in COVID-19 pneumonia

SARS-CoV-2 hijacks body's metabolism to amplify COVID-19 severity

MIS-C in children: A distinct autoimmune response to COVID-19 unveiled

Scientists unlock virus-fighting power with synthetic nanobody platform

Biologists discover a previously unknown way that the immune system detects viruses

Study may help advance data on oncolytic adenovirus mediated double suicide-gene therapy for high-grade brain tumors

Cryo-EM reveals key atomic structures of the ends of actin filament

Insilico Medicine nominates pan-TEAD inhibitor as a potential solution for drug resistance in solid tumor patients

Study uncovers novel mechanisms underlying plant immunity against major root disease

Study provides a new perspective on the aberrant nature of B cell phenotypes in skin cancer

DNA study sheds light on how we maintain healthy blood sugar levels after meals

Penn Medicine researchers receive $6 million NIH grant to gain new insights on cardiac cellular identity

Weak spot discovery could pave way for more effective cancer therapies

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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