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HIV and Hepatitis C vaccines now closer to reality

Plans for a new type of DNA vaccine to protect against the deadly HIV and Hepatitis C viruses have taken an important step forward, with University of Adelaide researchers applying for a patent based on groundbreaking new research.

26 Mar 2014

UMass Medical School students win 2014 Harold M. Weintraub Graduate Student Award

Colin Conine and Emma Watson, PhD students in the Graduate School of Biomedical Sciences (GSBS) at the University of Massachusetts Medical School, received the 2014 Harold M. Weintraub Graduate Student Award for research into the mechanisms governing epigenetic inheritance and the complex interactions between diet, gene expression and physiology.

26 Mar 2014

Scientists discover why cerebellar granule cell neurons in A-T patients fail to repair DNA damage

A team of scientists, led by Stuart Lipton, M.D., Ph.D., professor and director of the Neuroscience and Aging Research Center at Sanford-Burnham Medical Research Institute, recently discovered why cerebellar granule cell neurons in patients suffering from ataxia-telangiectasia (A-T) were unable to repair DNA damage and thus died.

26 Mar 2014

Axonics Modulation Technologies completes $32.6 million Series A preferred stock financing

Axonics Modulation Technologies, Inc., a developer of novel implantable neuromodulation technology, announced today that it has completed a $32.6 million Series A preferred stock financing.

25 Mar 2014

Protein known to promote cancer appears to give blood vessels strength and shape, researchers report

A protein known to promote cancer appears to give the blood vessels strength and shape, researchers report. When yes-associated protein, or YAP, is deleted from vascular smooth muscle cells during development, the protein makes thin-walled blood vessels that over-dilate in response to the usual pressure of blood flow, said Dr. Jiliang Zhou, vascular biologist at the Medical College of Georgia at Georgia Regents University.

25 Mar 2014

CytRx initiates Phase 3 clinical trial to evaluate efficacy of aldoxorubicin in STS patients

CytRx Corporation (Nasdaq: CYTR), a biopharmaceutical research and development company specializing in oncology, today announced it has initiated a pivotal global Phase 3 clinical trial to evaluate the efficacy and safety of aldoxorubicin as a second-line treatment for patients with soft tissue sarcoma (STS) under a Special Protocol Assessment with the FDA.

25 Mar 2014

High-protein meal and exercise recipe for calorie-burning in some women

New research shows that for some women, a high-protein meal followed by 30 minutes of moderate exercise is an effective way of burning calories, especially when compared to exercising on an empty stomach.

24 Mar 2014

New way to make large concentrations of skeletal muscle cells from human stem cells

As stem cells continue their gradual transition from the lab to the clinic, a research group at the University of Wisconsin-Madison has discovered a new way to make large concentrations of skeletal muscle cells and muscle progenitors from human stem cells.

24 Mar 2014

FDA approves Xolair for treatment of chronic idiopathic urticaria

Genentech, a member of the Roche Group, today announced that the U.S. Food and Drug Administration approved Xolair (omalizumab) for the treatment of chronic idiopathic urticaria, a form of chronic hives.

24 Mar 2014

Bariatric surgery reduces uterine cancer risk by 71%

Researchers at the University of California, San Diego School of Medicine and Moores Cancer Center report that bariatric surgery resulting in dramatic weight loss in formerly severely obese women reduces the risk of endometrial (uterine) cancer by 71 percent and as much as 81 percent if normal weight is maintained after surgery.

24 Mar 2014

Researchers identify genetic defect that causes a subset of irritable bowel syndrome

Is irritable bowel syndrome (IBS) caused by genetics, diet, past trauma, anxiety? All are thought to play a role, but now, for the first time, researchers have reported a defined genetic defect that causes a subset of IBS. The research was published in the journal Gastroenterology.

21 Mar 2014

Obesity: fat mass in cells expands with disuse

Over 35 percent of American adults and 17 percent of American children are considered obese, according to the latest survey conducted by the Centers for Disease Control and Prevention. Associated with diabetes, heart disease, stroke, and even certain types of cancer, obesity places a major burden on the health care system and economy. It's usually treated through a combination of diet, nutrition, exercise, and other techniques.

20 Mar 2014

Ipsen: Dysport Phase IIa clinical trial effective in treatment of NDO

Ipsen (Paris:IPN) (Euronext: IPN; ADR: IPSEY) today announced positive results from its phase IIa clinical trial assessing Dysport in the treatment of Neurogenic Detrusor Overactivity (NDO) in patients with urinary incontinence not adequately managed by anticholinergics.

19 Mar 2014

Building muscle mass important in decreasing metabolic risk

New UCLA research suggests that the more muscle mass older Americans have, the less likely they are to die prematurely. The findings add to the growing evidence that overall body composition - and not the widely used body mass index, or BMI - is a better predictor of all-cause mortality.

17 Mar 2014

Order of combined cardio- and resistance training does not affect long-term adaptations

Although the remarkable benefits of combined training have been clarified by numerous investigations, fitness enthusiasts struggle with the same question: Does the order of cardio- and resistance training influence the effectiveness of a training program?

17 Mar 2014

Researchers create statistical model to predict whether heart scans are useful in prescribing statins

As long as inexpensive statins, which lower cholesterol, are readily available and patients don't mind taking them, it doesn't make sense to do a heart scan to measure how much plaque has built up in a patient's coronary arteries before prescribing the pills, according to a new study by researchers at UC San Francisco.

17 Mar 2014

Scientists discover important mechanism for muscle building

In order to move the body, skeletal muscles are pulling on the skeleton. For efficient muscle and skeletal movements it is essential that the muscle contracts only along a defined axis, for instance for the leg movement along the thigh.

17 Mar 2014

Adherent stromal cells derived from human placenta improve tendon healing, shows study

According to Dr. Scott Rodeo of New York's Hospital for Special Surgery (HSS), although the findings of a recent study should be considered preliminary, adherent stromal cells derived from human placenta appear promising as a readily available cell source to aid tendon healing and regeneration.

17 Mar 2014

Edison Pharmaceuticals begins EPI-743 clinical trial in children with Pearson syndrome

Edison Pharmaceuticals today announced the initiation of a phase 2 study entitled "A Phase 2 Safety and Efficacy Study of EPI-743 (Vincerinone™) in Children with Pearson Syndrome." The Investigative New Drug application (IND) was approved by the Food and Drug Administration, Office of Hematology and Oncology Products.

17 Mar 2014

FDA grants Fast Track designation to Edison’s lead drug EPI-743

Edison Pharmaceuticals today announced that the United States Food and Drug Administration granted Fast Track designation to EPI-743, the company's lead drug, for the treatment of Friedreich's ataxia. EPI-743 is being developed for pediatric and adult mitochondrial disease, including Friedreich's ataxia.

17 Mar 2014

Muscle News and Research

HIV and Hepatitis C vaccines now closer to reality

UMass Medical School students win 2014 Harold M. Weintraub Graduate Student Award

Scientists discover why cerebellar granule cell neurons in A-T patients fail to repair DNA damage

Axonics Modulation Technologies completes $32.6 million Series A preferred stock financing

Protein known to promote cancer appears to give blood vessels strength and shape, researchers report

CytRx initiates Phase 3 clinical trial to evaluate efficacy of aldoxorubicin in STS patients

High-protein meal and exercise recipe for calorie-burning in some women

New way to make large concentrations of skeletal muscle cells from human stem cells

FDA approves Xolair for treatment of chronic idiopathic urticaria

Bariatric surgery reduces uterine cancer risk by 71%

Researchers identify genetic defect that causes a subset of irritable bowel syndrome

Obesity: fat mass in cells expands with disuse

Ipsen: Dysport Phase IIa clinical trial effective in treatment of NDO

Building muscle mass important in decreasing metabolic risk

Order of combined cardio- and resistance training does not affect long-term adaptations

Researchers create statistical model to predict whether heart scans are useful in prescribing statins

Scientists discover important mechanism for muscle building

Adherent stromal cells derived from human placenta improve tendon healing, shows study

Edison Pharmaceuticals begins EPI-743 clinical trial in children with Pearson syndrome

FDA grants Fast Track designation to Edison’s lead drug EPI-743

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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