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Severe COVID linked to RAAS and hyperlipidemia associated metabolic syndrome conditions

A recent study posted to the medRxiv* preprint server investigated the association of renin-angiotensin-aldosterone system (RAAS)-mediated hypertension (HT) with coronavirus disease 2019 (COVID-19).

6 Apr 2022

High-throughput screening assay could identify new prostate cancer drugs

A novel high-throughput screening assay is designed to identify inhibitors of the androgen receptor, which plays a critical role in the progression of prostate cancer.

6 Apr 2022

UCI researchers reveal the impact of native lipids on rhodopsin signaling and regeneration

In a new study at University of California, Irvine, researchers have revealed the impact of native lipids on rhodopsin signaling and regeneration, which may usher in a new paradigm for discovery of drugs that target G protein-coupled receptors (GPCRs).

6 Apr 2022

Researchers develop novel device to “cleanse” the blood of chemotherapeutic drugs

For patients with cancer, the tumor-killing power of chemotherapeutic drugs is a double-edged sword. While many cancer drugs kill tumor cells, they can also harm healthy cells as they travel throughout the bloodstream.

6 Apr 2022

Cryo-EM imaging of a key immune protein reveals previously unrecognized binding site

Imaging at near-atomic resolution of a key immune protein commonly known as STING has revealed a previously unrecognized binding site that appears to be pivotal for launching immune attacks, UT Southwestern scientists report in a new study.

6 Apr 2022

Wastewater-based Epidemiology technique can help move toward a healthier and more sustainable world

Of the many contemporary conveniences often taken for granted in developed countries, modern sanitation may be among the most important. A new study suggests that wastewater infrastructure may provide societal benefits far beyond the dramatic improvements in community hygiene.

6 Apr 2022

Paternal use of diabetes drug associated with genital birth defects in boys

Boys were more likely to be born with genital birth defects if their fathers took the commonly prescribed diabetes drug metformin in the three months before conception, according to a new study by Stanford Medicine investigators and their collaborators in Denmark.

6 Apr 2022

$11M for North Carolina work-based rehab raises concerns

An addiction treatment facility, highly regarded by North Carolina lawmakers, sits in a residential neighborhood here and operates like a village in itself.

6 Apr 2022

Doctors trying to prescribe abortion pills across state lines stymied by legislation

Soon after Dr. Mai Fleming finished her medical residency in the San Francisco Bay Area, she got to work on her Texas medical license.

6 Apr 2022

Why Black and Hispanic seniors are left with a less powerful flu vaccine

At Whitman-Walker Health, Dr. David Fessler and his staff administer high-dose influenza vaccine to all HIV-positive and senior patients.

6 Apr 2022

New study finds community acquired drug-resistant UTIs to be more deadly

A new study led by Australia’s national science agency, CSIRO, has found the spread of drug-resistant bacteria in the community is increasing the risk of death for common infections such as urinary tract infections (UTIs), which affect around one in two women and one in 20 men in their lifetime.

6 Apr 2022

Gut bacterium may be an important factor in resistance to antihypertensive medications

Almost half of the U.S. adult population has high blood pressure - or hypertension - and about 20% of these patients have treatment-resistant hypertension.

5 Apr 2022

Combining two biomarkers could help identify patients with subcortical small-vessel disease

In recent years, subcortical small-vessel disease has become an increasingly common cognitive diagnosis.

5 Apr 2022

HIV drug stops disease progression in 25% of patients with fourth-line metastatic colorectal cancer

New clinical research shows that lamivudine, a reverse transcriptase inhibitor widely used in HIV therapy, stopped disease progression in 25% of patients with fourth-line metastatic colorectal cancer.

5 Apr 2022

Patients treated with edoxaban after TAVR do not find reduction in mini strokes, blood clots in the brain

Patients treated with the blood thinner edoxaban for six months after a heart valve replacement procedure experienced fewer symptomless blood clots inside the heart valve replacement than patients who were treated with two antiplatelet drugs, according to data presented at the American College of Cardiology's 71st Annual Scientific Session.

5 Apr 2022

Novel transcatheter repair system for tricuspid regurgitation shows promising results at one year

Patients with tricuspid regurgitation, a common and debilitating form of valvular heart disease, who received a novel investigational device intended to repair the defective valve experienced significant improvements in blood flow through the heart and in quality of life at one year, according to research presented at the American College of Cardiology's 71st Annual Scientific Session.

5 Apr 2022

A critical subset of fibroblasts may lie at the origins of rare autoimmune disease

Supporting actors sometimes steal the show. In a new study published today in Cell, researchers headed by Prof. Ido Amit at the Weizmann Institute of Science have shown that supporting cells called fibroblasts, long viewed as uniform background players, are in fact extremely varied and vital.

5 Apr 2022

Drugs News and Research

Severe COVID linked to RAAS and hyperlipidemia associated metabolic syndrome conditions

High-throughput screening assay could identify new prostate cancer drugs

UCI researchers reveal the impact of native lipids on rhodopsin signaling and regeneration

Researchers develop novel device to “cleanse” the blood of chemotherapeutic drugs

Cryo-EM imaging of a key immune protein reveals previously unrecognized binding site

Wastewater-based Epidemiology technique can help move toward a healthier and more sustainable world

Paternal use of diabetes drug associated with genital birth defects in boys

$11M for North Carolina work-based rehab raises concerns

Doctors trying to prescribe abortion pills across state lines stymied by legislation

Why Black and Hispanic seniors are left with a less powerful flu vaccine

New study finds community acquired drug-resistant UTIs to be more deadly

Gut bacterium may be an important factor in resistance to antihypertensive medications

Combining two biomarkers could help identify patients with subcortical small-vessel disease

HIV drug stops disease progression in 25% of patients with fourth-line metastatic colorectal cancer

Patients treated with edoxaban after TAVR do not find reduction in mini strokes, blood clots in the brain

Novel transcatheter repair system for tricuspid regurgitation shows promising results at one year

A critical subset of fibroblasts may lie at the origins of rare autoimmune disease

Improving our understanding of a severe pregnancy sickness (Hyperemesis Gravidarum)

Study provides new insights into cause of metastasis in prostate cancer

Vitamin C may help to counteract common side effect of the chemotherapy drug

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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