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Scientists develop stem cell based method for restoring strength to damaged skeletal muscles in elderly

A study co-published in Nature Medicine this week by University of Toronto researcher Penney Gilbert has determined a stem cell based method for restoring strength to damaged skeletal muscles of the elderly.

24 Feb 2014

Cell therapy: A powerful treatment for cancer patients

Investigators from Memorial Sloan Kettering Cancer Center have reported more encouraging news about one of the most exciting methods of cancer treatment today. The largest clinical study ever conducted to date of patients with advanced leukemia found that 88 percent achieved complete remissions after being treated with genetically modified versions of their own immune cells.

24 Feb 2014

Researchers find new drug compound that treats laboratory mice with congenital heart disease

Congenital heart disease is the most common form of birth defect, affecting one out of every 125 babies, according to the National Institutes of Health. Researchers from the University of Missouri recently found success using a drug to treat laboratory mice with one form of congenital heart disease, hypertrophic cardiomyopathy - a weakening of the heart caused by abnormally thick muscle.

23 Feb 2014

Regional anesthesia may not make patients more prone to falls after knee replacement surgery

Two types of regional anesthesia do not make patients more prone to falls in the first days after having knee replacement surgery as some have previously suggested, according to a study based on nearly 200,000 patient records in the March issue of Anesthesiology.

21 Feb 2014

Study finds Cyclin A2 protein induces cardiac regeneration after myocardial infarction

After a heart attack, there is often permanent damage to a portion of the heart. This happens, in part, because cardiac muscle cells are terminally differentiated and cannot proliferate after blood flow is blocked off to the heart.

20 Feb 2014

AlloMap test can be used to assess risk of dysfunction or rejection of a transplanted heart

A new UCLA-led study shows that a blood test commonly used to determine whether heart transplant recipients are rejecting their new organ can also predict potential rejection-related problems in the future.

19 Feb 2014

Rhythm important for correct development of baby hearts

To develop correctly, baby hearts need rhythm...even before they have blood to pump.

19 Feb 2014

Viewpoints: Refusing a mammogram; video monitoring in hospitals; peril of low-T marketing

A selection of editorials and opinions on health care from around the country.

19 Feb 2014

Study: 85% of patients who have heart attacks after surgery do not experience traditional symptoms

Without administering a simple blood test in the first few days after surgery, 85 percent of the heart attacks or injuries patients suffer could be missed, according to a study in the March issue of Anesthesiology.

19 Feb 2014

Discovery could lead to improved early detection, prevention strategies for sudden cardiac death

UC Irvine researchers have found a specific genetic flaw that is connected to sudden death due to heart arrhythmia - a leading cause of mortality for adults around the world.

18 Feb 2014

Phasefocus’ KTP associate Dr Suman receives runners up spot for Cellular Heaven and Hell time-lapse video

Phase Focus Ltd (Phasefocus), the company that is revolutionizing microscopy and imaging with the Phasefocus Virtual Lens® technology, reports on the Celldance competition results held at the recent annual ASCB meeting. KTP associate, Dr Rakesh Suman, was runner up with his video entitled "Cellular Heaven & Hell."

From Phase Focus Limited 18 Feb 2014

New research may provide insight on how dengue virus gains entry into cells

Dengue fever, an infectious tropical disease caused by a mosquito-borne virus, afflicts millions of people each year, causing fever, headache, muscle and joint pains and a characteristic skin rash. In some people the disease progresses to a severe, often fatal, form known as dengue hemorrhagic fever.

18 Feb 2014

New therapeutic target may help repair muscle damage

Researchers at the Stanford University School of Medicine have pinpointed why normal aging is accompanied by a diminished ability to regain strength and mobility after muscle injury: Over time, stem cells within muscle tissues dedicated to repairing damage become less able to generate new muscle fibers and struggle to self-renew.

18 Feb 2014

Scientists discover link between ageing process and hormone released from muscle after exercise

Scientists from Aston University (UK) have discovered a potential molecular link between Irisin, a recently identified hormone released from muscle after bouts of exercise, and the ageing process.

18 Feb 2014

Mini-sling partially successful for stress urinary incontinence

A mini-sling that requires a single incision may be a viable alternative to the “gold standard” transobturator midurethral sling for the treatment of stress urinary incontinence, a randomised controlled trial has found.

17 Feb 2014

Study points to unique therapeutic approach for managing muscle-wasting conditions

New findings on why skeletal muscle stem cells stop dividing and renewing muscle mass during aging points up a unique therapeutic opportunity for managing muscle-wasting conditions in humans, says a new University of Colorado Boulder study.

17 Feb 2014

FAST-MAG clinical trial finds that magnesium does not improve stroke-related disability

In the first study of its kind, a consortium led by UCLA physicians found that giving stroke patients intravenous magnesium within an hour of symptom onset does not improve stroke outcomes, according to research presented today at the American Stroke Association's International Stroke Conference.

14 Feb 2014

Sarcopenia increases risk of sepsis risk in patients undergoing live donor liver transplantation

Japanese researchers have determined that sarcopenia—a loss of skeletal muscle mass—increases risk of sepsis and mortality risk in patients undergoing live donor liver transplantation.

14 Feb 2014

Prothelia, University of Nevada, Reno and Alexion partner to develop Laminin-111 for MDC1A

Prothelia Incorporated and University of Nevada, Reno announce that they have entered into strategic agreements with Alexion for the development of Laminin-111, a patented experimental protein replacement therapy for merosin-deficient congenital muscular dystrophy (MDC1A), a life-threatening, ultra-rare disease caused by a genetic deficiency of the Laminin-211 protein.

13 Feb 2014

Study: Metabolic risk factors cluster similarly in children and adults

Metabolic risk factors cluster similarly in children and adults, according to a study carried out at the University of Eastern Finland. Furthermore, in adults, the clustering of these risk factors increases the risk of premature death caused by type 2 diabetes, myocardial infarction and cardiovascular diseases.

13 Feb 2014

Muscle News and Research

Scientists develop stem cell based method for restoring strength to damaged skeletal muscles in elderly

Cell therapy: A powerful treatment for cancer patients

Researchers find new drug compound that treats laboratory mice with congenital heart disease

Regional anesthesia may not make patients more prone to falls after knee replacement surgery

Study finds Cyclin A2 protein induces cardiac regeneration after myocardial infarction

AlloMap test can be used to assess risk of dysfunction or rejection of a transplanted heart

Rhythm important for correct development of baby hearts

Viewpoints: Refusing a mammogram; video monitoring in hospitals; peril of low-T marketing

Study: 85% of patients who have heart attacks after surgery do not experience traditional symptoms

Discovery could lead to improved early detection, prevention strategies for sudden cardiac death

Phasefocus’ KTP associate Dr Suman receives runners up spot for Cellular Heaven and Hell time-lapse video

New research may provide insight on how dengue virus gains entry into cells

New therapeutic target may help repair muscle damage

Scientists discover link between ageing process and hormone released from muscle after exercise

Mini-sling partially successful for stress urinary incontinence

Study points to unique therapeutic approach for managing muscle-wasting conditions

FAST-MAG clinical trial finds that magnesium does not improve stroke-related disability

Sarcopenia increases risk of sepsis risk in patients undergoing live donor liver transplantation

Prothelia, University of Nevada, Reno and Alexion partner to develop Laminin-111 for MDC1A

Study: Metabolic risk factors cluster similarly in children and adults

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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