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NIAID-funded clinical trial of Ebola vaccines is underway at Cincinnati Children's

A Phase 1 clinical trial of investigational vaccines intended to protect against Zaire ebolavirus (Ebola) is underway at Cincinnati Children's Hospital Medical Center in the United States. The study is sponsored by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

28 Jan 2019

New class of antisense oligonucleotide therapeutics tested in humans

A first-in-human study with a new class of antisense oligonucleotide therapeutics showed the ability to target the RNA-silencing drug to the liver, resulting in improved potency and safety at therapeutic doses. The design and results of this trial, conducted in healthy human volunteers are reported in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers.

28 Jan 2019

Injection of opioids may increase infective endocarditis risk

People who inject drugs are at a high risk for a number of health issues. In a new study from ICES, Lawson Health Research Institute and Western University, researchers discovered a significant rise in the risk of infective endocarditis, a serious heart infection, among Ontarians who inject drugs.

28 Jan 2019

Type of saturated fats consumed could affect cardiovascular heath, analysis shows

The type of saturated fats we eat can affect our risk of a heart attack, according to a study published in the International Journal of Cardiology. People whose diets contain relatively little palmitic and stearic acid - saturated fats composed of 16 or more carbon atoms (longer-chain saturated fats) that are typically found in meats - and eat plant-based proteins instead have decreased chances of myocardial infarction.

28 Jan 2019

Discovery reveals how to 'slim down' fat-carrying particles to reduce spread of 'bad' cholesterol

The enzyme that 'loads up' fat-carrying particles in the liver before they are transported around the body has been identified for the first time by scientists at the University of Warwick.

28 Jan 2019

Genetic testing to be provided by the NHS in exchange for genomic data

The NHS is going to start providing genetic tests in exchange for patients in England who agree to share their genomic data so that it can be used for research.

28 Jan 2019

New research collaboration between EU and Russia focuses on infectious diseases

A new EU project on the theme of HIV, hepatitis C and tuberculosis is a door opener for collaboration between researchers from EU countries and Russia.

28 Jan 2019

Stress and paradoxical sleep associated with pathways of brain cell death and survival

The first and most distinct consequence of daily mild stress is an increase in rapid-eye-movement (REM) sleep, a new study in the journal PNAS reports. The research also demonstrated that this increase is associated with genes involved in cell death and survival.

28 Jan 2019

Scientists create 3D human epidermal equivalent using mathematical model

Scientists have successfully constructed a three-dimensional human epidermis based on predictions made by their mathematical model of epidermal homeostasis, providing a new tool for basic research and drug development.

28 Jan 2019

Scientists are working to develop a new way to detect Zika virus

A collaboration of scientists including Professor Jean Patterson, Ph.D., of Texas Biomedical Research Institute, is working on a new way to detect Zika virus that will help guide clinicians in their treatment of patients with the disease.

28 Jan 2019

Researchers highlight the need for pediatricians to discuss firearm safety

Paradoxically, as overall firearm ownership decreased in U.S. households with young children from 1976 to 2016, the proportion of these families who owned handguns increased.

28 Jan 2019

Mechanism of inflammation initiation through NLRP3 inflammasome activation revealed

Inflammation is the response of our immune system to infection and harmful environmental effects. On one hand, it is beneficial as it defends our body against microbes. On the other hand, excessive inflammation leads to serious diseases.

28 Jan 2019

Home Help Service in Valencia is better with public funding, study reveals

A study produced by researchers of the Universitat de València specifies what the care work consists of and what the different delivery systems are.

28 Jan 2019

New research reveals that prescription opioids are used long-term to treat severe osteoarthritis

New research published in Arthritis & Rheumatology, an official journal of the American College of Rheumatology, reveals that prescription opioids are commonly used long-term to treat pain in older patients with severe osteoarthritis.

28 Jan 2019

Study identifies new genetic variant associated with ARDS

An international study in which Javier Belda, Professor of Surgery at the University of Valencia and Incliva researcher, participated, has identified a new genetic variant associated with Acute Respiratory Distress Syndrome.

28 Jan 2019

Researchers discover immune regulator that appears to dictate glioblastoma

Researchers at The University of Texas MD Anderson Cancer Center have discovered an immune regulator that appears to dictate glioblastoma progression by shutting down immune surveillance, indicating a potential new area of therapeutic investigation.

28 Jan 2019

Gluten-free wheat can be produced for people with celiac disease by using gene editing

One to two per cent of the population has Celiac Disease (CD), an immune reaction to gluten. Wheat grains contain gluten, a mixture of glutenin and gliadin proteins, which build a network that gives wheat bread its unique properties and quality.

28 Jan 2019

American adults assume boys to be in more pain than girls

Gender stereotypes can hurt children -- quite literally. When asked to assess how much pain a child is experiencing based on the observation of identical reactions to a finger-stick, American adults believe boys to be in more pain than girls, according to a new Yale study in the Journal of Pediatric Psychology.

28 Jan 2019

'Bug bombs' are ineffective at removing cockroaches from indoor environments

Total release foggers, commonly known as "bug bombs," are ineffective at removing cockroaches from indoor environments, according to a new study from North Carolina State University.

28 Jan 2019

Heavy pressures at work seem to predispose women to weight gain

Heavy pressures at work seem to predispose women to weight gain, irrespective of whether they have received an academic education. This is shown in a study of more than 3,800 people in Sweden.

28 Jan 2019

Research News and Research

NIAID-funded clinical trial of Ebola vaccines is underway at Cincinnati Children's

New class of antisense oligonucleotide therapeutics tested in humans

Injection of opioids may increase infective endocarditis risk

Type of saturated fats consumed could affect cardiovascular heath, analysis shows

Discovery reveals how to 'slim down' fat-carrying particles to reduce spread of 'bad' cholesterol

Genetic testing to be provided by the NHS in exchange for genomic data

New research collaboration between EU and Russia focuses on infectious diseases

Stress and paradoxical sleep associated with pathways of brain cell death and survival

Scientists create 3D human epidermal equivalent using mathematical model

Scientists are working to develop a new way to detect Zika virus

Researchers highlight the need for pediatricians to discuss firearm safety

Mechanism of inflammation initiation through NLRP3 inflammasome activation revealed

Home Help Service in Valencia is better with public funding, study reveals

New research reveals that prescription opioids are used long-term to treat severe osteoarthritis

Study identifies new genetic variant associated with ARDS

Researchers discover immune regulator that appears to dictate glioblastoma

Gluten-free wheat can be produced for people with celiac disease by using gene editing

American adults assume boys to be in more pain than girls

'Bug bombs' are ineffective at removing cockroaches from indoor environments

Heavy pressures at work seem to predispose women to weight gain

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