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Study shows potential inhibition of SARS-CoV-2 main protease by natural phytochemicals

A new study assessed the molecular dynamics of potentially active natural phytochemicals to target the SARS-CoV-2 main protease.

29 Mar 2022

Study reveals a deeper level of cellular heterogeneity within fallopian tubes

The fallopian tube is the site of fertilization, where once a month for the duration of a female's post-pubescent, pre-menopausal life, an egg is moved from the ovary, ready for fertilization by a sperm cell.

29 Mar 2022

At a Tennessee crossroads, two pharmacies, a monkey, and millions of pills

It was about 1 a.m. on April 19, 2016, when a burglary alarm sounded at Dale Hollow Pharmacy in Celina, a tiny town in the rolling, wooded hills near the Kentucky border.

29 Mar 2022

Algal metabolites as novel drugs against viruses

A new review article published in the Journal of Biotechnology has provided information on various nutraceutical metabolites extracted from algae.

29 Mar 2022

Strand displacement mechanism in RNA appears to switch genetic expression from “on” to “off”

Similar to a light switch, RNA switches (called riboswitches) determine which genes turn "on" and "off." Although this may seem like a simple process, the inner workings of these switches have confounded biologists for decades.

29 Mar 2022

New compound delivered in a nasal spray effectively treats delta variant infection in mice

Researchers have shown a new compound delivered in a nasal spray is highly effective in preventing and treating COVID-19 caused by the Delta variant in mice.

29 Mar 2022

Researchers use optoacoustics for high-precision neuromodulation

Neuromodulation plays an important role in deciphering neural circuits and exploring clinical treatment of neurological diseases.

28 Mar 2022

Novel drug combination can boost chemoimmunotherapy response in bladder cancer patients

Adding an anti-inflammatory medication to immunotherapy and standard chemotherapy drugs may provide long-term suppression of aggressive bladder tumor growth, according to a proof-of-concept study led by Cedars-Sinai Cancer investigators.

28 Mar 2022

Depression occurs independently of inflammation for many older people, study suggests

Multiple prior studies have found higher levels of inflammation in older individuals with depression. Now, a new Penn Medicine study has found that clinically depressed older individuals, on average, don't have elevated levels of inflammation if they don't already have other inflammatory conditions such as arthritis.

28 Mar 2022

Big pharma is betting on bigger political ambitions from Sen. Tim Scott

Sen. Tim Scott, a rising star in the Republican Party with broad popularity in his home state of South Carolina, is getting showered with drug industry money before facing voters this fall.

28 Mar 2022

Mathematical model of SARS-CoV-2 transmission tailored to the unique situation of China

Researchers designed a dynamic mathematical model to simulate the transmission of the SARS-CoV-2 Omicron variant in China and project its associated burden on healthcare facilities, should the zero-COVID-19 policy be lifted.

28 Mar 2022

How malaria drugs could play a part in treating chemotherapy-resistant head and neck cancers

In this interview, we speak to Kirill Kiselyov, Ph.D, and Umamaheswar Duvvuri, M.D, Ph.D, from the University of Pittsburgh, about their latest research into hydroxychloroquine, a drug widely used to prevent and treat malaria, as a potential treatment for head and neck cancers.

28 Mar 2022

CDK6: a potential drug target for severe COVID-19

Researchers identify a methodology and workflow to repurpose drugs against the cyclin-dependent kinase 6 target gene of SARS-CoV-2.

27 Mar 2022

Clinical determinants of post-COVID-19 thromboembolism

Researchers quantify the risk of acute VTE due to SARS-CoV-2 infection in ambulatory settings.

27 Mar 2022

Novel ACL reconstruction technique in younger patients garners positive results two years post-surgery

A new study by researchers at Hospital for Special Surgery in New York City presented today at the American Academy of Orthopaedic Surgeons 2022 Annual Meeting found that a novel surgical technique performed during anterior cruciate ligament (ACL) reconstruction in certain younger patients garnered positive results two years post-surgery.

27 Mar 2022

HIV patients on antiretroviral treatment with protease inhibitors may have lower COVID-19 risk

A preliminary study to be presented at this year's European Congress of Clinical Microbiology & Infectious Diseases in Lisbon, Portugal (23-26 April), suggests that people living with HIV who are on antiretroviral treatment (ART) with protease inhibitors (PI), may have a lower risk of COVID-19 infection.

27 Mar 2022

Exploring the vital connection between gut microbes, physical activity, and health

Our bowels accommodate billions of active microbes that affect the health, a fact that is arousing increasing interest also among athletes.

26 Mar 2022

New method for generating binding proteins solves a long-standing challenge in drug development

A team of scientists has created a powerful new method for generating protein drugs. Using computers, they designed molecules that can target important proteins in the body, such as the insulin receptor, as well as vulnerable proteins on the surface of viruses.

25 Mar 2022

New trial examines the effectiveness of a two-pronged immunotherapy for glioblastomas

A new clinical trial at the University of Cincinnati is studying the effectiveness of a new two-pronged immunotherapy treatment procedure to treat the most aggressive and deadly type of brain tumors, called glioblastomas. Originating from healthy brain cells, glioblastomas can form in any area of the brain.

25 Mar 2022

Researchers show how an important inhibitor binds to the A2A receptor

The A2A receptor regulates how vigorously the innate immune system attacks diseased cells.

25 Mar 2022

Drugs News and Research

Study shows potential inhibition of SARS-CoV-2 main protease by natural phytochemicals

Study reveals a deeper level of cellular heterogeneity within fallopian tubes

At a Tennessee crossroads, two pharmacies, a monkey, and millions of pills

Algal metabolites as novel drugs against viruses

Strand displacement mechanism in RNA appears to switch genetic expression from “on” to “off”

New compound delivered in a nasal spray effectively treats delta variant infection in mice

Researchers use optoacoustics for high-precision neuromodulation

Novel drug combination can boost chemoimmunotherapy response in bladder cancer patients

Depression occurs independently of inflammation for many older people, study suggests

Big pharma is betting on bigger political ambitions from Sen. Tim Scott

Mathematical model of SARS-CoV-2 transmission tailored to the unique situation of China

How malaria drugs could play a part in treating chemotherapy-resistant head and neck cancers

CDK6: a potential drug target for severe COVID-19

Clinical determinants of post-COVID-19 thromboembolism

Novel ACL reconstruction technique in younger patients garners positive results two years post-surgery

HIV patients on antiretroviral treatment with protease inhibitors may have lower COVID-19 risk

Exploring the vital connection between gut microbes, physical activity, and health

New method for generating binding proteins solves a long-standing challenge in drug development

New trial examines the effectiveness of a two-pronged immunotherapy for glioblastomas

Researchers show how an important inhibitor binds to the A2A receptor

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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