Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Aggressive management of diabetes with diet, exercise, and medications may improve the survival of cancer patients

Researchers at Fox Chase Cancer Center found no effects of type II diabetes on aggressiveness of prostate cancer but found that long-term survival is worse. The findings were presented at the 47th Annual Meeting of the American Society for Therapeutic Radiology and Oncology in Denver, Colo.

16 Oct 2005

Severe hypoglycemia - complication of gastric bypass surgery

Physicians monitoring patients who have undergone gastric bypass surgery should be on the alert for a new, potentially dangerous hypoglycemia (low blood glucose) complication that, while rare, may require quick treatment, according to a new study

12 Oct 2005

Sleletal muscle findings highlight the importance of exercise in obese people

The findings suggest that muscle bears a metabolic memory of obesity, which may help to explain why sustained weight loss can be difficult despite cutting calories, according to the researchers. Exercise might more successfully override the aberrant metabolic program in muscle, they suggest, thereby improving the long-term prognosis of those prone to obesity.

11 Oct 2005

Vanadium may help prepare the body to recover speedily from infections

Dietary supplements containing vanadium are used by body builders to help beef up muscles and by some diabetic people to control blood sugar. New research now suggests the naturally occurring but easily toxic element may help prepare the body to recover speedily from infections from gram-negative organisms such as E. coli.

11 Oct 2005

Actos reduces the combined risk of non-fatal heart attacks, strokes in patients with type-2 diabetes

A study published in The Lancet shows that Takeda's Actos (pioglitazone HCl), an oral glucose lowering medication, significantly reduces the combined risk of non-fatal heart attacks, strokes and deaths by an additional 16% on top of standard medication

10 Oct 2005

Obese Zucker rat model shares the symptoms of obesity with a growing number of Americans

A mutant rat that mimics a 400-pound human is helping scientists understand early vascular changes that make walking a pain for more than 2 million Americans.

9 Oct 2005

To improve the diets of British children we need to look beyond school dinners

The health of pupils eating school dinners is no worse - and in some respects may be better - than that of pupils eating meals provided from home, concludes a study published online by the British Medical Journal today.

5 Oct 2005

Children enrolled in fitness-oriented gym classes showed greater loss of body fat

Overweight children who took part in lifestyle-focused, fitness-oriented gym classes showed significant improvement in body composition, fitness, and insulin levels, according to a study in the October issue of Archives of Pediatrics and Adolescent Medicine.

3 Oct 2005

Fruit fly discovery could lead to a completely new approach to tackling some cancers

Scientists studying the humble fruit fly have found a family of proteins that enhances the sensitivity of a cell to a hormone that can trigger abnormal growth and cancer. Their discovery could lead to a completely new approach to tackling some cancers and the development of new drugs to stop uncontrolled growth in a wide variety of tumour cells.

28 Sep 2005

Treatment of Nonalcoholic Fatty Liver Disease (NAFLD) in children

The Nonalcoholic Steatohepatitis (NASH) Clinical Research Network has launched its second clinical trial to study NASH, a liver disease that resembles alcoholic liver disease but occurs in patients who drink little or no alcohol. The first trial, launched in January of this year, focuses on adults, while the second trial studies the disease in children.

27 Sep 2005

Transplanted insulin-producing cells survive better when the activation of NKT cells are blocked

Scientists in Japan have found a way to improve on a promising diabetes treatment. In the October 3 issue of The Journal of Experimental Medicine, Masaru Taniguchi and colleagues report that transplanted insulin-producing cells survive better when the activation of a specific type of immune cell is blocked.

27 Sep 2005

Pursuit of potential drugs and small molecules that target the IGF-1 receptor

Pharmaceutical companies around the world still come knocking on Renato Baserga, M.D.,'s door. And for good reason.

27 Sep 2005

Plans to develop a "universal beta-cell line" - treatment for type 1 diabetes

Transplantation of insulin-producing pancreatic beta-cells shows great promise as a treatment for type 1 diabetes, but development of this therapy has been hampered by a severe shortage of donor beta-cells, which are obtained from decreased human donors.

26 Sep 2005

Increlex - first major innovation in 20 years for the treatment of growth failure

Rush University Medical Center is participating in a clinical trial to evaluate the potential benefit of the first major innovation in 20 years for the treatment of growth failure.

26 Sep 2005

Chronically high levels of insulin may block specific hormones that trigger energy release into the body

Their findings, which may point to new approaches to developing improved treatment options for the disease, are published in the journal Nature.

26 Sep 2005

Smoking may increase the risk of developing diabetes

The surprising finding emerged when researchers examined the relationship between smoking and diabetes among participants in a major national study, the Insulin Resistance Atherosclerosis Study (IRAS).

26 Sep 2005

Study clarifies insulin's role in blocking release of energy in patients with type II diabetes

Chronically high levels of insulin, as is found in many people with obesity and Type II diabetes, may block specific hormones that trigger energy release into the body, according to researchers at the University of California, San Diego (UCSD) School of Medicine.

22 Sep 2005

Study reveals critical molecular events in the origin of fat cells

A new study reveals critical molecular events in the origin of fat cells. The findings are central to understanding chronic diseases, such as obesity and diabetes, as fat cells produce hormones critical for metabolic control, the researchers said.

21 Sep 2005

Significant death risk linked to airborne particles

Experts may be significantly underestimating air pollution's role in causing early death, according to a team of American and Canadian researchers, who studied two decades' worth of data on residents of the Los Angeles metro area.

20 Sep 2005

High-fat fare increases risk of heart disease for hospital staff and visitors

Nutrition scientists with the Physicians Committee for Responsible Medicine (PCRM) have conducted a nationwide survey to determine if hospital cafeterias and restaurants are meeting the need for low-fat, cholesterol-free foods that can help people maintain a healthy weight and prevent heart disease, diabetes, and some cancers.

19 Sep 2005

Insulin News and Research

Further Reading

Aggressive management of diabetes with diet, exercise, and medications may improve the survival of cancer patients

Severe hypoglycemia - complication of gastric bypass surgery

Sleletal muscle findings highlight the importance of exercise in obese people

Vanadium may help prepare the body to recover speedily from infections

Actos reduces the combined risk of non-fatal heart attacks, strokes in patients with type-2 diabetes

Obese Zucker rat model shares the symptoms of obesity with a growing number of Americans

To improve the diets of British children we need to look beyond school dinners

Children enrolled in fitness-oriented gym classes showed greater loss of body fat

Fruit fly discovery could lead to a completely new approach to tackling some cancers

Treatment of Nonalcoholic Fatty Liver Disease (NAFLD) in children

Transplanted insulin-producing cells survive better when the activation of NKT cells are blocked

Pursuit of potential drugs and small molecules that target the IGF-1 receptor

Plans to develop a "universal beta-cell line" - treatment for type 1 diabetes

Increlex - first major innovation in 20 years for the treatment of growth failure

Chronically high levels of insulin may block specific hormones that trigger energy release into the body

Smoking may increase the risk of developing diabetes

Study clarifies insulin's role in blocking release of energy in patients with type II diabetes

Study reveals critical molecular events in the origin of fat cells

Significant death risk linked to airborne particles

High-fat fare increases risk of heart disease for hospital staff and visitors

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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