Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Novel compound may help fight obesity

A new study reveals an attractive new target for therapies aimed at the treatment of obesity and related metabolic disorders, researchers report in the March Cell Metabolism.

9 Mar 2006

MannKind initiates two phase 3 studies of inhaled Technosphere insulin

MannKind Corporation has announced that it has initiated patient enrollment in two pivotal 12-month Phase 3 clinical trials of Technosphere Insulin (TI) in patients with Type 1 and Type 2 Diabetes.

7 Mar 2006

Genes play a key role in stress response

Both nature and nurture - genetic makeup and the environment experienced through life - combine to influence health and well-being, Duke University Medical Center researchers and their colleagues have determined in four new studies.

7 Mar 2006

Study may lead to ways to reduce heart attacks in diabetes patients

For people with type 2 diabetes, the death rate from a first heart attack is two to three times the death rate of patients without the disease. Similarly, patients with diabetes and ischemic (reduced blood flow) heart disease have a much higher mortality rate than the general population.

7 Mar 2006

SSRI use associated with increased risk for heart patients

In a surprising finding, patients with coronary artery disease who take commonly used antidepressant drugs may be at significantly higher risk of death, Duke University Medical Center researchers have found.

7 Mar 2006

Pfizer acquires worldwide rights to Exubera

Pfizer has announced that it has acquired the sanofi-aventis worldwide rights to Exubera (inhaled human insulin). Pfizer received approval last month to market Exubera in the United States and the European Union for the treatment of adults with type 1 and type 2 diabetes.

1 Mar 2006

Compound found in marijuana may defend against diabetic retinopathy

A compound found in marijuana won't make you high but it may help keep your eyes healthy if you're a diabetic, researchers say.

1 Mar 2006

Researchers transplant insulin-producing neonatal porcine islet cells into monkeys

A team of researchers from the University of Alberta, the Yerkes National Primate Research Center of Emory University and the Emory Transplant Center has successfully transplanted insulin-producing neonatal porcine islet cells into monkeys, a procedure the researchers say represents a promising intermediate solution to the critical supply problem in clinical islet cell transplantation.

27 Feb 2006

Potatoes increase risk of diabetes

Researchers at Harvard University are warning that people who love to eat potatoes run the risk of diabetes.

27 Feb 2006

Relationship between periodontal disease, obesity and insulin

The relationship between periodontal disease, obesity and insulin resistance was examined in the Third National Health and Nutrition Examination Survey (NHANES III).

23 Feb 2006

Pig cells reverse diabetes in monkeys

A team of researchers in the U.S. have successfully reversed diabetes in monkeys using transplanted islet cells from pigs.

21 Feb 2006

Removing a gene involved in repairing damaged DNA causes metabolic syndrome

Removing a gene involved in repairing damaged DNA causes mice to develop the metabolic syndrome, researchers at Oregon Health & Science University have discovered.

21 Feb 2006

Inflammatory reaction drives hormone resistance in cancer

In the journal Cell, researchers report new evidence to explain why prostate cancer and other hormone-dependent cancers may become resistant to hormone therapies.

21 Feb 2006

Lifetime calorie restraint to prevent obesity is the most powerful way to reduce age-related health problems

University of South Florida researcher Barbara Hansen, PhD, will likely never be invited to talk about weight loss on Oprah. Her message is mundanely common sense, not faddish - she doesn't drop phrases like "low carb," or "low fat," or "geared to your body type" or "put your body into fat-burning mode."

20 Feb 2006