Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

French may be headed for similar obesity and heart problems as U.S.

Just 2 pounds of weight gain can greatly increase a person's risk for the metabolic syndrome, a dangerous condition that can lead to type 2 diabetes and coronary heart disease, finds a Kaiser Permanente study.

7 Feb 2006

Chromium helps muscles become more efficient

Researchers found that daily use of chromium picolinate enhanced muscle sensitivity to insulin in obese, insulin-resistant rats

7 Feb 2006

Monotherapy phase I clinical trials of novel cytotoxics, targeted therapeutics, antimetastatic agents/angiogenesis inhibitors, and immunotherapeutics/vaccines

Numerous novel oncology agents are currently in phase I monotherapy trials. New Medicine's Oncology KnowledgeBASE (nm|OK) has updated the records of 92 such agents with preclinical or clinical results reported during the 2005 meetings of the American Association for Cancer Research (AACR)

7 Feb 2006

Pollution may increase heart attack risk for obese

A University of Alberta researcher believes obese humans face same dangers from diesel exhaust and coal emissions.

7 Feb 2006

Diet rich in whole-grain foods may lower heart disease risk in elderly people

With the recent revision of the Food Guide Pyramid, the Dietary Guidelines for Americans have for the first time provided the public with a quantitative recommendation for whole-grain intake.

7 Feb 2006

First description of female-specific Ischemia Syndrome

Although ischemic heart disease - the reduction of blood flow that can lead to heart attacks - is often considered a "man's disease," it takes the lives of more women than men each year. In fact, in 2000, about 60,000 more women than men died from cardiovascular disease.

5 Feb 2006

Link between high levels of a protein HtrA1 and preeclampsia

Mayo Clinic researchers have found an association between abnormally high levels of a protein named HtrA1 and preeclampsia, a sudden and dangerous rise in blood pressure that can result in premature delivery, disability or death for mother and fetus.

5 Feb 2006

Obesity may accelerate the onset of type 1 diabetes in some

Obesity, long known as a cause of type II diabetes, may accelerate the onset of type 1 diabetes in some - but not all - groups of younger patients, according to research at Wake Forest University School of Medicine and six clinical sites nationally.

5 Feb 2006

Can rimonabant slow atherosclerosis?

Researchers at the University of Rochester Medical Center has announced that they have launched a study to determine whether an experimental drug, rimonabant, can slow atherosclerosis, the fatty build-up in arteries that creates heart attack risk.

2 Feb 2006

New inhaled drug for diabetics an alternative treatment option for some

The Food and Drug Administration (FDA) in the U.S. has given it's approval for the sale of a new drug to treat diabetes.

29 Jan 2006

$More fractures, less bone density in premenopausal women with diabetes$

More fractures, less bone density in premenopausal women with diabetes

Premenopausal women who have type 1 diabetes should strongly consider preventive screening for osteoporosis, the researchers of a new study on bone density conclude in the February issue of Diabetes Care.

27 Jan 2006

Patent losses open up $30 billion biologics market to generic competition

With powerhouse biologics, such as human growth hormone and insulin, losing their U.S. patent protection in 2005 and many more set to expire within the next 4 years, generic competition in the lucrative biopharmaceutical market is imminent, according to a new study from Kalorama Information.

25 Jan 2006

Metabolic syndrome - a new risk factor for impaired kidney function

A three-year multi-center study of kidney-pancreas transplant recipients has identified a new risk factor for impaired kidney function, which may help physicians refine their treatment strategies.

23 Jan 2006

Caretek Medical signs feasibility agreement with major pharma for protein based drug

Caretek Medical Ltd, an Oxford-based company developing an innovative needle-free drug delivery system, today announced that it has signed a feasibility study agreement with a major global pharmaceutical company.

19 Jan 2006

UIC surgeons first to use robot for living-donor kidney-pancreas transplant

Surgeons at the University of Illinois Medical Center at Chicago are the first in the world to use robotic surgery to successfully remove a kidney and pancreas from a living-donor as part of a successful transplantation.

19 Jan 2006

New findings about messenger molecule raise hopes for new drug

Uppsala University scientists have developed a new method for measuring the concentration of the messenger substance for cells, cyclic adenosine monophosphate (cAMP), in individual living cells.

18 Jan 2006

Variation in IGF1 gene may play a role in prostate cancer risk

Two variations in the gene for insulin-like growth factor I (IGF-1) are linked to an increased risk of prostate cancer, according to research performed by scientists from the Keck School of Medicine of the University of Southern California, the Broad Institute of Harvard and MIT, and the University of Hawaii.

18 Jan 2006

Diabetes gene found in 40% of population

Researchers in Iceland say they have identified a single genetic change which could predispose close to 40 percent of the population to type-2 diabetes.

16 Jan 2006

Brain plays a major role in the ability of insulin therapy to lower blood sugar in animals with diabetes

"Our findings suggest that, in individuals with diabetes, the ability of insulin to lower blood sugar involves the brain," said senior author of the study, Michael Schwartz of the University of Washington at Seattle. "This effect is not trivial; the brain makes a substantial contribution to insulin response."

10 Jan 2006

Carbohydrates improve insulin control

It is commonly believed that carbohydrates, particularly sugar, are a cause of insulin resistance and type 2 diabetes. However, such thinking has been challenged following the publication of a thorough appraisal of the evidence, in the latest edition of Nutrition Research Reviews.

10 Jan 2006