Amino Acid News and Research

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Amino Acid is one of several molecules that join together to form proteins. There are 20 common amino acids found in proteins.

SARS-CoV-2 spike subunit conformation determines plasma-neutralizing activity triggered by COVID-19 vaccines and natural infection

In a new study, researchers evaluated the effect of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein conformation on S-directed neutralizing antibodies (nAbs).

14 Nov 2022

Blood samples from healthy individuals have pre-existing anti-SARS-CoV-2 IgGs and IVIg may be an effective therapy for severe COVID-19

A new paper introduces evidence of effective alleviation of disease severity using intravenous immunoglobulin (IVIg).

14 Nov 2022

The viral fitness and antigenic relationship among Omicron sublineages

Researchers used mouse models and human airway cell cultures to investigate the relative viral replication rates and cross-neutralization against SARS-CoV-2 Omicron sublineages.

14 Nov 2022

A knowledgebase of currently known categorized COVID-19 severity variants

In a recent study posted to the medRxiv* preprint server, researchers assessed human genome variants related to the susceptibility and severity of coronavirus disease 2019 (COVID-19).

10 Nov 2022

The roles of innate and adaptive immunity in Alzheimer’s disease development and progression

Researchers reviewed research advancements showing the significant role both innate and adaptive immune systems play in the pathological course of Alzheimer’s disease.

10 Nov 2022

Researchers propose a deep antibody-antigen interaction algorithm to accelerate the identification of potential therapeutic antibodies

Researchers used a deep antibody-antigen interaction (DeepAAI) algorithm to understand the antibody representations of unseen antibodies to accelerate the discovery of novel antibodies with potential therapeutic applications.

9 Nov 2022

Study indicates widespread SARS-CoV-2 exposure in wildlife

In a recent study posed to the bioRxiv* preprint server, researchers at Virginia Tech University investigated wildlife exposure to SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2).

8 Nov 2022

Researchers identify 55 broadly reactive monoclonal antibodies to betacoronaviruses

In a recent study published in the journal Cell Host & Microbe, researchers pursued novel approaches that could help find monoclonal antibodies (mAbs) broadly targeting coronaviruses (CoVs), especially genera beta CoVs.

8 Nov 2022

Study identifies novel inhibitors against SARS-CoV-2 main protease

In a recent study posted to the bioRxiv* server, researchers at the University of Arizona screened ~11 million severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (MPro)-inhibiting small compounds in the ZINC15 database using a structure-based in-silico screening method.

8 Nov 2022

New method to estimate the contribution of each amino acid residue

You can't expect a pharmaceutical scientist to switch labs to the facilities available in a television studio and expect the same research output. Enzymes behave exactly the same. But now, in a study recently published in ACS Synthetic Biology, researchers from Osaka University have imparted an analogous level of adaptability to enzymes, a goal that has remained elusive for over 30 years.

3 Nov 2022

Study finds possible treatment strategy for Feingold syndrome type 1

A decrease in protein synthesis in cells of the developing gut contributes to a rare genetic disorder, and an inexpensive nutritional supplement may help reverse that decrease, according to a new study publishing November 1st in the open access journal PLOS Biology by Yun-Fei Li of Zhejiang University School of Medicine in Hangzhou, China, and colleagues. The finding is an advance in understanding the pathogenesis of the disease, and may lead to new treatments.

2 Nov 2022

Study provides more nuanced insights into RNA modifications by A-to-I editing during brain development

Mount Sinai researchers have cataloged thousands of sites in the brain where RNA is modified throughout the human lifespan in a process known as adenosine-to-inosine (A-to-I) editing, offering important new avenues for understanding the cellular and molecular mechanisms of brain development and how they factor into both health and disease.

1 Nov 2022

Amino Acid News and Research

Further Reading

SARS-CoV-2 spike subunit conformation determines plasma-neutralizing activity triggered by COVID-19 vaccines and natural infection

Blood samples from healthy individuals have pre-existing anti-SARS-CoV-2 IgGs and IVIg may be an effective therapy for severe COVID-19

The viral fitness and antigenic relationship among Omicron sublineages

A knowledgebase of currently known categorized COVID-19 severity variants

The roles of innate and adaptive immunity in Alzheimer’s disease development and progression

Researchers propose a deep antibody-antigen interaction algorithm to accelerate the identification of potential therapeutic antibodies

Study indicates widespread SARS-CoV-2 exposure in wildlife

Researchers identify 55 broadly reactive monoclonal antibodies to betacoronaviruses

Study identifies novel inhibitors against SARS-CoV-2 main protease

New method to estimate the contribution of each amino acid residue

Study finds possible treatment strategy for Feingold syndrome type 1

Study provides more nuanced insights into RNA modifications by A-to-I editing during brain development

New method helps gain fundamental insights into ribosome function

What is the impact of SARS-CoV-2 on HIV-1 infectivity?

Study reports on a novel property of antibodies, light chain coherence

Study refutes the nicotinic hypothesis of SARS-CoV-2 infection mechanism

Discovery provides better understanding of retinal protein's structure and function

SARS-CoV-2 BQ.1 variant cases may increase in Europe

Interrupting prolonged sitting with periodic activity "snacks" may help maintain muscle mass, study says

Bovine ultralong complementarity-determining region H3 found to cross-react with sarbecoviruses

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