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Tau protein reduces neural activity in Alzheimer's mouse models

A study from Massachusetts General Hospital investigators sheds new light on how the hallmarks of Alzheimer's disease - amyloid-beta (A-beta) plaques and neurofibrillary tangles containing the protein tau - produce their damaging effects in the brain.

19 Dec 2018

FAU Brain Institute fellows awarded $1.1 million for Alzheimer's disease research

In Florida, there are more than 540,000 people living with Alzheimer's disease (AD), the most recognized form of dementia. The number of people in Florida who are age 65 and older with AD is expected to increase 41.2 percent by 2025 to a projected 720,000, highlighting the urgency of finding medical and treatment breakthroughs.

19 Dec 2018

New study uses intracranial recordings to investigate memory development

Declarative memory -- memories that can be consciously recalled -- is critical to everyday life. Throughout childhood and adolescence, declarative memory improves remarkably. However, until most recently, there was a critical gap in our understanding of how maturation of the prefrontal cortex drives memory development.

19 Dec 2018

Study uncovers initial folding mechanism of membrane proteins, key in design of new drugs

An international team coordinated by the Interdisciplinary Research Structure in Biotechnology and Biomedicine of the University of Valencia has proved how the folding of membrane proteins begins before they are inserted into biological membranes, a fact that has been central to the biochemical research for decades.

19 Dec 2018

$Type 2 diabetes drug may be used to treat heart failure with preserved ejection fraction$

Type 2 diabetes drug may be used to treat heart failure with preserved ejection fraction

Researchers at the University of Arizona have discovered that metformin, a drug commonly used to treat type 2 diabetes, might also be used to treat heart failure with preserved ejection fraction, a condition that is predicted to affect over 8% of people ages 65 or older by the year 2020.

19 Dec 2018

MUSC researchers identify potential therapeutic target for lung fibrosis

In an article published online by Frontiers in Endocrinology, researchers at the Medical University of South Carolina report that they have identified a potential therapeutic target for lung fibrosis or scarring.

19 Dec 2018

Viral hepatitis: Liver failure caused by defects in the vascular system

In severe cases, a viral hepatitis infection can result in liver failure. A team from the Technical University of Munich has now discovered how this occurs: by immune cells attacking cells in the vascular system, which disrupts the organ's blood and nutrient supply.

19 Dec 2018

Study investigates why mammals' sense of smell deteriorates in old age

As mammals age, their sense of smell deteriorates. In a study published in the journal 'Cell Reports', an interdisciplinary research team at Helmholtz Zentrum München and the University Medical Centre Mainz investigated why this is the case.

19 Dec 2018

Obesity help on the front line

The Australian National University (ANU) has developed a new program to be rolled out across the country to help GPs treat patients with obesity.

19 Dec 2018

Self-powered bandage generates electricity, reduces healing time for skin wounds in rats

Skin has a remarkable ability to heal itself. But in some cases, wounds heal very slowly or not at all, putting a person at risk for chronic pain, infection and scarring. Now, researchers have developed a self-powered bandage that generates an electric field over an injury, dramatically reducing the healing time for skin wounds in rats.

19 Dec 2018

GABA cells help fight alcohol dependence, study finds

Scientists of the Higher School of Economics, Indiana University, and École normale supérieure clarified how alcohol influences the dopamine and inhibitory cells in the midbrain that are involved in the reward system and the formation of dependency on addictive drugs.

19 Dec 2018

Universal meningitis vaccination for college students may be too costly, study suggests

A computer-generated model developed by Johns Hopkins Medicine researchers adds to evidence that providing universal vaccination against meningitis B infection to students entering college may be too costly to justify the absolute number of cases it would prevent.

19 Dec 2018

Genetically modified houseplant can efficiently detoxify indoor air

Our homes are supposed to be safe havens from the outside world. However, studies have shown that household air is more polluted than either office or school air, exposing children and home workers to higher levels of carcinogens than the general population.

19 Dec 2018

Kidney failure is increasing in Australians under 50 with type 2 diabetes, study finds

A study of more than 1.3 million Australians with diabetes has found that kidney failure is increasing in people with type 2 diabetes aged under 50 years, leading to reduced quality of life and placing growing demand on the country's kidney dialysis and transplantation services.

19 Dec 2018

Consumption of milk cereal drinks in infancy associated with twofold overweight risk

In five-year-old children, the risk for overweight is almost twice as high if they at 12 months had consumed milk cereal drinks every day, a study in the journal Acta Paediatrica shows.

19 Dec 2018

Researchers uncover genes that play a key role in the inactivation of X chromosomes

In cell biology, men and women are unequal: men have an X chromosome, while women have two. How can we get around this difference?

19 Dec 2018

Galectins play a key role in the degeneration of cartilage in osteoarthritis

A network of carbohydrate binding proteins - so-called galectins - plays an important role in the degeneration of cartilage in osteoarthritis.

19 Dec 2018

Personalization techniques give a new lease of life to anticancer vaccines

Anticancer vaccines have gained a new lease of life with techniques to personalise them to individual patients.

19 Dec 2018

Hep C and drug abuse often go hand in hand, but screening for infection lags

When people seek help at a drug treatment center for an opioid addiction, concerns about having contracted hepatitis C are generally low on their list.

19 Dec 2018

Active ingredient in eye drops shows promise for treating aggressive blood cancer

An active ingredient in eye drops that were being developed for the treatment of a form of eye disease has shown promise for treating an aggressive form of blood cancer. Scientists at the Wellcome Sanger Institute, University of Cambridge, University of Nottingham and their collaborators have found that this compound, which targets an essential cancer gene, could kill leukemia cells without harming non-leukemic blood cells.

19 Dec 2018

Research News and Research

Tau protein reduces neural activity in Alzheimer's mouse models

FAU Brain Institute fellows awarded $1.1 million for Alzheimer's disease research

New study uses intracranial recordings to investigate memory development

Study uncovers initial folding mechanism of membrane proteins, key in design of new drugs

Type 2 diabetes drug may be used to treat heart failure with preserved ejection fraction

MUSC researchers identify potential therapeutic target for lung fibrosis

Viral hepatitis: Liver failure caused by defects in the vascular system

Study investigates why mammals' sense of smell deteriorates in old age

Obesity help on the front line

Self-powered bandage generates electricity, reduces healing time for skin wounds in rats

GABA cells help fight alcohol dependence, study finds

Universal meningitis vaccination for college students may be too costly, study suggests

Genetically modified houseplant can efficiently detoxify indoor air

Kidney failure is increasing in Australians under 50 with type 2 diabetes, study finds

Consumption of milk cereal drinks in infancy associated with twofold overweight risk

Researchers uncover genes that play a key role in the inactivation of X chromosomes

Galectins play a key role in the degeneration of cartilage in osteoarthritis

Personalization techniques give a new lease of life to anticancer vaccines

Hep C and drug abuse often go hand in hand, but screening for infection lags

Active ingredient in eye drops shows promise for treating aggressive blood cancer

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