Clinical Trial News and Research

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Researchers identify attractive drug candidate to target glioma tumors

In a paper published today in Cancer Research, researchers: 1) identify a biomarker enzyme associated with aggressive glioma brain tumors, 2) reveal the regulatory mechanism for that enzyme, and 3) demonstrate potent efficacy, using a mouse model of glioma, for a small molecule inhibitor they have developed.

16 Dec 2016

Over-the-counter antioxidant may promote reductions in alcohol use in marijuana-dependent teens

An over-the-counter antioxidant known as N-acetylcysteine (NAC) is showing early promise at promoting abstinence from or reduced use of alcohol in marijuana-dependent adolescents, report researchers at the Medical University of South Carolina (MUSC) in the December 2016 Addictive Behaviors.

15 Dec 2016

Magnesium supplementation could help reduce risk of strokes, diabetes and heart disease

A study by scientists at Zhejiang University in China claimed that eating a magnesium rich Mediterranean diet could combat a range of diseases (such as strokes, diabetes and heart disease) linked to magnesium deficiency.

From BetterYou Ltd 14 Dec 2016

Phenotypic Personalized Medicine could surmount treatment challenges for acute lymphoblastic leukemia

A team of UCLA bioengineers has demonstrated that its technology may go a long way toward overcoming the challenges of treatment for acute lymphoblastic leukemia, among the most common types of cancer in children, and has the potential to help doctors personalize drug doses.

14 Dec 2016

Common anti-cholesterol drugs show promise for reducing Alzheimer's disease risk

Common anti-cholesterol drugs show promise for reducing the risk of Alzheimer's disease, a University of Southern California-led study of Medicare data reveals.

14 Dec 2016

Innovation in stroke aftercare across Europe: an interview with Professor Urs Fischer

Stroke is the epidemic disease of the twenty-first century and the second most frequent cause of death in 2011, accounting for 11% of all deaths worldwide. Stroke is also the second most important cause of permanent disability and...

13 Dec 2016

Depression drug can alleviate joint pain in postmenopausal women treated for breast cancer

A drug typically used to treat depression and anxiety can significantly reduce joint pain in postmenopausal women being treated for early stage breast cancer, according to new SWOG research to be presented Friday at a special plenary presentation at the San Antonio Breast Cancer Symposium.

9 Dec 2016

Image-guided percutaneous needle biopsies after NST identify breast cancer patients who achieve pCR

In a pilot study conducted at The University of Texas MD Anderson Cancer Center, image-guided biopsies identified select breast cancer patients who achieved pathologic complete response (pCR) after chemotherapy and/or targeted therapy, neoadjuvant systemic therapy (NST).

9 Dec 2016

Personalized cancer vaccine improves outcomes for patients with AML, clinical study shows

A personalized cancer vaccine markedly improved outcomes for patients suffering from acute myeloid leukemia (AML), a potentially lethal blood cancer, in a clinical trial led by investigators at Beth Israel Deaconess Medical Center.

9 Dec 2016

ABIVAX reports preclinical data on first-in-class drug candidate for functional cure of HIV/AIDS patients

ABIVAX an innovative biotechnology company targeting the immune system to eliminate viral disease, announced today that the Company presented new preclinical data on ABX464, ABIVAX's first-in-class drug candidate for a functional cure of patients with HIV/AIDS, during this week's HIV DART scientific conference in Los Cabos, Mexico.

9 Dec 2016

Study shows experimental treatment not superior to standard therapy for head and neck cancer

Results of the largest Canadian clinical trial to date comparing standard treatment for locally advanced squamous cell head and neck cancer with an experimental treatment, did not show the new treatment is superior.

9 Dec 2016

Scientists identify biomarkers to predict patient’s response to breast cancer treatment

Why do some breast cancers respond to treatment while others resist it? A study led by researchers at the University of North Carolina Lineberger Comprehensive Cancer Center may provide insight into this important question.

8 Dec 2016

New contact lens therapy effective in slowing progression of juvenile-onset myopia, study shows

A groundbreaking contact lens therapy has potential to impact the fast-growing issue of myopia (nearsightedness) among children, based on research presented at the American Academy of Optometry's 95th Annual Meeting.

8 Dec 2016

Stem cell-based risk scoring tool could predict AML patient’s response to standard treatment

Leukemia researchers at Princess Margaret Cancer Centre have developed a 17-gene signature derived from leukemia stem cells that can predict at diagnosis if patients with acute myeloid leukemia (AML) will respond to standard treatment.

8 Dec 2016

Older women with metastatic breast cancer more likely to have genetic alterations in tumors

A University of North Carolina Lineberger Comprehensive Cancer Center-led analysis has found that women who are 65 years or older with metastatic breast cancer were more likely to have a cancer-linked genetic alterations in their tumors, and had a larger total number of genetic alterations, than younger patients overall.

7 Dec 2016

Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

A new investigational drug originally developed for type 2 diabetes is being readied for human clinical trials in search of the world's first treatment to impede the progression of Parkinson's disease following publication of research findings today in the journal Science Translational Medicine.

7 Dec 2016

Pathogenic variants in certain genes increase woman's likelihood of developing breast cancer

Inherited pathogenic variants in protein coding genes BARD1 and RAD51D increase a woman's likelihood of developing breast cancer, according to research conducted at Mayo Clinic and presented today at the 2016 San Antonio Breast Cancer Symposium.

7 Dec 2016

Brazilian researchers propose new way for treating thalassemia major

Iron accumulation in myocardial cells, potentially resulting in heart failure or fatal arrhythmia, is one of the complications most feared by patients with thalassemia major, a hereditary disease also known as Mediterranean anemia.

7 Dec 2016

New research reveals role of two genetic mutations in subset of acute myeloid leukemia

Two genetic mutations known to play a role in many solid cancers might also help explain why a subset of acute myeloid leukemia (AML) patients develop the disease, according to new research from The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

7 Dec 2016

Detecting inflammation in diabetic patients

As well as presenting with high blood glucose, diabetic patients have chronic low-grade inflammation, which can be measured by a range of inflammatory markers such as so-called high-sensitive CRP, TNFa and IL-6 as well as a full blood cell count.

7 Dec 2016

Clinical Trial News and Research

Researchers identify attractive drug candidate to target glioma tumors

Over-the-counter antioxidant may promote reductions in alcohol use in marijuana-dependent teens

Magnesium supplementation could help reduce risk of strokes, diabetes and heart disease

Phenotypic Personalized Medicine could surmount treatment challenges for acute lymphoblastic leukemia

Common anti-cholesterol drugs show promise for reducing Alzheimer's disease risk

Innovation in stroke aftercare across Europe: an interview with Professor Urs Fischer

Depression drug can alleviate joint pain in postmenopausal women treated for breast cancer

Image-guided percutaneous needle biopsies after NST identify breast cancer patients who achieve pCR

Personalized cancer vaccine improves outcomes for patients with AML, clinical study shows

ABIVAX reports preclinical data on first-in-class drug candidate for functional cure of HIV/AIDS patients

Study shows experimental treatment not superior to standard therapy for head and neck cancer

Scientists identify biomarkers to predict patient’s response to breast cancer treatment

New contact lens therapy effective in slowing progression of juvenile-onset myopia, study shows

Stem cell-based risk scoring tool could predict AML patient’s response to standard treatment

Older women with metastatic breast cancer more likely to have genetic alterations in tumors

Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

Pathogenic variants in certain genes increase woman's likelihood of developing breast cancer

Brazilian researchers propose new way for treating thalassemia major

New research reveals role of two genetic mutations in subset of acute myeloid leukemia

Detecting inflammation in diabetic patients

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