Stroke News and Research

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A stroke is a medical emergency. Strokes happen when blood flow to your brain stops. Within minutes, brain cells begin to die. There are two kinds of stroke. The more common kind, called ischemic stroke, is caused by a blood clot that blocks or plugs a blood vessel in the brain. The other kind, called hemorrhagic stroke, is caused by a blood vessel that breaks and bleeds into the brain. "Mini-strokes" or transient ischemic attacks (TIAs), occur when the blood supply to the brain is briefly interrupted.

CTE can be diagnosed by neuropathological examination of brain tissue

For the first time, CTE has been confirmed as a unique disease that can be definitively diagnosed by neuropathological examination of brain tissue. A consensus panel of expert neuropathologists concluded that CTE has a pathognomonic signature in the brain, an advance that represents a milestone for CTE research and lays the foundation for future studies defining the clinical symptoms, genetic risk factors and therapeutic strategies for CTE.

16 Dec 2015

Kitov Pharmaceuticals' KIT-302 drug candidate meets primary efficacy endpoint in Phase III clinical trial

Kitov Pharmaceuticals, an innovative biopharmaceutical company focused on late-stage drug development, announced today that the Phase III, double-blind, placebo-controlled clinical trial for its leading drug candidate, KIT-302, successfully met the primary efficacy endpoint of the trial protocol as approved by the U.S. Food & Drug Administration (FDA).

15 Dec 2015

Irradiated white blood cells release substances that have positive effect upon tissue repair

Hendrik Jan Ankersmit's research group at the Clinical Department of Thoracic Surgery of MedUni Vienna has successfully shown that irradiated white blood cells release substances that reduce the severity of the damage caused by a heart attack or stroke and in spinal injuries and have a positive effect upon tissue repair. However, up until now it wasn't known exactly which particular substances were responsible for these beneficial effects. This has now been discovered.

14 Dec 2015

Identifying and avoiding wasteful or unnecessary medical tests

Too many tests at the doctor's office could cost you more than just dollars. In addition to the huge hit to your wallet, there's also the potential harm of false positives, and just because a test has traditionally been done for a condition doesn't mean it's the best way to treat it.

13 Dec 2015

ER stroke cases have some degree of preventability, UCI study shows

Many strokes that required immediate treatment in emergency rooms may have been preventable, according to a University of California, Irvine study.

11 Dec 2015

FDA grants Fast Track status to Cardiorentis' Ularitide for treatment of ADHF

Cardiorentis AG, a privately held biopharmaceutical company, today announced that the U.S. Food and Drug Administration has granted Fast Track status to Ularitide, an investigational therapy for the treatment of acute decompensated heart failure (ADHF).

11 Dec 2015

UC San Diego's Comprehensive Stroke Center receives Gold Plus Award

When someone experiences a major stroke, almost two million nerve cells in the brain die each minute, emphasizing the need for rapid treatment. Stroke patients who receive life-saving interventions more quickly have a higher chance of recovery. A recent data analysis showed the Comprehensive Stroke Center at UC San Diego Medical Center exceeded national average treatment times, and as a result, has received a "Get With The Guidelines-Stroke Gold Plus Quality Achievement Award" from The American Heart Association and American Stroke Association.

11 Dec 2015

UB physicians testing new exercise treatment for concussion

The standard of care for acute concussion may undergo a dramatic change, depending on the results of a new exercise treatment that physicians at the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo have developed and begun testing. It is the first randomized, controlled clinical trial of this exercise treatment for concussion.

11 Dec 2015

Specific deep-brain circuit's firing frequency can alter forebrain activity, alertness levels

Adjusting a specific deep-brain circuit's firing frequency immediately and dramatically alters rats' forebrain activity and alertness levels, Stanford University School of Medicine investigators have shown.

11 Dec 2015

Two UK studies reveal apparent increase in healthy ageing, less severe disability

Two studies conducted 20 years apart in England reveal an apparent increase in healthy ageing, or years lived healthily, reflecting less cognitive impairment; and an increase in the proportion of life lived healthily, through a larger proportion of years lived with disability but less rather than more severe disability.

10 Dec 2015

Researchers identify brain processes in mice that shape different sensory perceptions

Scientists have long known that when sounds are faint or objects are seen through fog in the distance, repetition of these weak or ambiguous sensory “inputs” can result in different perceptions inside the same brain.

10 Dec 2015

VNS technology could help improve lives of people recovering from stroke

A new study involving UT Dallas researchers shows that vagus nerve stimulation (VNS) technology could help improve the lives of hundreds of thousands of people who suffer weakness and paralysis caused by strokes.

10 Dec 2015

Telemedicine brings prehospital thrombolysis closer

Telemedicine allows prehospital stroke assessment and thrombolysis without the need for a neurologist at the scene, a study shows.

9 Dec 2015

Tetra begins human Phase 1 safety trials of BPN14770

Tetra Discovery Partners today announced that the company has initiated human Phase 1 safety trials of its lead compound BPN14770, which Tetra is developing as a potential treatment to both improve memory and slow the progression of Alzheimer's disease.

9 Dec 2015

Treatment with antiplatelet therapy does not reduce pain crises in children with sickle cell disease

Treatment with the antiplatelet agent prasugrel does not significantly reduce the rate of pain crises or severe lung complications in children with sickle cell disease, according to a report published in the New England Journal of Medicine describing one of the largest and most geographically diverse international clinical trials on sickle cell disease to date.

9 Dec 2015

XARELTO reduces rates of major bleeding, recurrent blood clots in people with deep vein thrombosis

Janssen Pharmaceuticals, Inc. and its development partner, Bayer HealthCare, today announced the results from their real-world study XALIA showing that, in people with deep vein thrombosis (DVT), the rates of major bleeding and recurrent blood clots for XARELTO (rivaroxaban) in routine clinical practice were generally consistent with those observed in Phase 3 research.

7 Dec 2015

Research shows significant step toward improving outcomes, reducing treatment burden for SCD patients

Emerging therapies and promising new insights in the treatment of sickle cell disease represent a significant step toward improving outcomes and reducing the treatment burden for affected children and adults. Studies reporting these advances will be presented today at the 57th American Society of Hematology Annual Meeting and Exposition.

7 Dec 2015

Stroke News and Research

Further Reading

CTE can be diagnosed by neuropathological examination of brain tissue

Kitov Pharmaceuticals' KIT-302 drug candidate meets primary efficacy endpoint in Phase III clinical trial

Irradiated white blood cells release substances that have positive effect upon tissue repair

Identifying and avoiding wasteful or unnecessary medical tests

ER stroke cases have some degree of preventability, UCI study shows

FDA grants Fast Track status to Cardiorentis' Ularitide for treatment of ADHF

UC San Diego's Comprehensive Stroke Center receives Gold Plus Award

UB physicians testing new exercise treatment for concussion

Specific deep-brain circuit's firing frequency can alter forebrain activity, alertness levels

Two UK studies reveal apparent increase in healthy ageing, less severe disability

Researchers identify brain processes in mice that shape different sensory perceptions

VNS technology could help improve lives of people recovering from stroke

Telemedicine brings prehospital thrombolysis closer

Tetra begins human Phase 1 safety trials of BPN14770

Treatment with antiplatelet therapy does not reduce pain crises in children with sickle cell disease

XARELTO reduces rates of major bleeding, recurrent blood clots in people with deep vein thrombosis

Research shows significant step toward improving outcomes, reducing treatment burden for SCD patients

New article shows that intake of sugar-sweetened beverages is increasing worldwide

HBsAg may persist in chronic HBV patients beyond seroclearance

Combining medications may increase HBsAg loss in HBV patients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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