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The effectiveness of nirmatrelvir in preventing severe COVID-19 outcomes during the Omicron surge

Researchers assessed the clinical efficacy of nirmatrelvir in preventing severe COVID-19 in Israel during the Omicron wave.

29 Aug 2022

Preliminary study shows tecovirimat was well tolerated by patients with monkeypox

Researchers investigated the usage of tecovirimat against monkeypox infections.

29 Aug 2022

The incidence rate, distribution, characteristics, and outcomes of neonatal COVID-19

Researchers assessed the epidemiology of neonatal COVID-19 infections.

29 Aug 2022

$Research shows benefit of dapagliflozin for heart failure patients regardless of ejection fraction$

Research shows benefit of dapagliflozin for heart failure patients regardless of ejection fraction

Dapagliflozin reduces the risks of death and cardiovascular events in patients with heart failure regardless of ejection fraction, according to late-breaking research presented in a Hot Line session today at ESC Congress 2022.

28 Aug 2022

$SGLT2 inhibitors reduce cardiovascular events among heart failure patients with mildly reduced and preserved ejection fraction$

SGLT2 inhibitors reduce cardiovascular events among heart failure patients with mildly reduced and preserved ejection fraction

An analysis of more than 12,000 patients has found that the SGLT2 inhibitors dapagliflozin and empagliflozin reduce cardiovascular death or hospitalization for heart failure by 20% in heart failure patients with mildly reduced and preserved ejection fraction.

28 Aug 2022

Percutaneous coronary intervention provides no benefit in patients with severe left ventricular dysfunction

Percutaneous coronary intervention (PCI) does not reduce all-cause mortality or heart failure hospitalization in patients with severe left ventricular dysfunction and extensive coronary artery disease, according to late breaking research presented in a Hot Line session today at ESC Congress 2022.

28 Aug 2022

Gout medicine fails to improve cardiovascular outcomes in patients with ischemic heart disease

The gout medicine allopurinol has failed to reduce the primary endpoint of nonfatal myocardial infarction, nonfatal stroke or cardiovascular death in patients with ischaemic heart disease, according to late breaking research presented in a Hot Line session today at ESC Congress 2022.

28 Aug 2022

Target blood pressure of 77 mmHg provides no benefit for comatose cardiac arrest survivors

A target blood pressure of 77 mmHg provides no benefit to survival or neurological outcome in comatose cardiac arrest survivors compared with a 63 mmHg target, according to late breaking research presented in a Hot Line session today at ESC Congress 2022.

28 Aug 2022

Restrictive oxygenation target in comatose, post cardiac arrest patients does not cause harm

A restrictive oxygenation target in comatose patients resuscitated after out-of-hospital cardiac arrest does not worsen survival or neurological outcome compared with a liberal target, according to late breaking research presented in a Hot Line session today at ESC Congress 2022.

28 Aug 2022

Adding acetazolamide to intravenous loop diuretics decreases congestion in patients with acute decompensated heart failure

Acetazolamide added to intravenous loop diuretics decreases congestion within three days in patients with acute decompensated heart failure, according to late breaking research presented in a Hot Line session today at ESC Congress 2022.

28 Aug 2022

New advice aims to reduce the cardiac side effects of cancer treatment

The first European Society of Cardiology Guideline on cardio-oncology is published online today in European Heart Journal.

26 Aug 2022

Study explores a potential new therapeutic approach for triple negative breast cancer treatment

Researchers are exploring a potential new therapeutic approach for triple negative breast cancer treatment.

26 Aug 2022

Healthy people over 65 years of age recommended to get a heart check-up before non-cardiac surgery

A heart check-up is recommended in even apparently healthy people over 65 years of age before intermediate- or high-risk non-cardiac surgery, according to European Society of Cardiology (ESC) Guidelines on cardiovascular assessment and management of patients undergoing non-cardiac surgery published online today in European Heart Journal.

26 Aug 2022

New guidelines recommend earlier detection and treatment of pulmonary hypertension

Earlier detection of pulmonary hypertension in the community and expedited referral of high-risk or complex patients are recommended in the European Society of Cardiology (ESC) and European Respiratory Society (ERS) Guidelines for the diagnosis and treatment of pulmonary hypertension, published online today in European Heart Journal and the European Respiratory Journal.

26 Aug 2022

Three-drug medication effective in preventing recurrent cardiovascular events after a heart attack

A three-drug medication known as a "polypill," developed by the Spanish National Center for Cardiovascular Research (CNIC) and Ferrer, is effective in preventing secondary adverse cardiovascular events in people who have previously had a heart attack, reducing cardiovascular mortality by 33 percent in this patient population.

26 Aug 2022

Heavy smoking and smoke inhalation linked to poor prognosis after a heart attack

The risk of death or poor prognosis after a heart attack is more than 20-fold higher in smokers with exhaled carbon monoxide levels above 13 ppm, indicating heavy smoking and inhalation of smoke.

26 Aug 2022

Immune therapy may be an alternate therapeutic approach for treating chronic hepatitis B

Hepatitis B virus (HBV) infection is global in nature and induces several incredible liver diseases, such as chronic hepatitis B (CHB), cirrhosis of the liver (LC) and hepatocellular carcinoma (HCC). A total of 882,000 patients died of HBV-related liver diseases in 2019.

25 Aug 2022

Therapy News and Research

The effectiveness of nirmatrelvir in preventing severe COVID-19 outcomes during the Omicron surge

Preliminary study shows tecovirimat was well tolerated by patients with monkeypox

The incidence rate, distribution, characteristics, and outcomes of neonatal COVID-19

Research shows benefit of dapagliflozin for heart failure patients regardless of ejection fraction

SGLT2 inhibitors reduce cardiovascular events among heart failure patients with mildly reduced and preserved ejection fraction

Percutaneous coronary intervention provides no benefit in patients with severe left ventricular dysfunction

Gout medicine fails to improve cardiovascular outcomes in patients with ischemic heart disease

Target blood pressure of 77 mmHg provides no benefit for comatose cardiac arrest survivors

Restrictive oxygenation target in comatose, post cardiac arrest patients does not cause harm

Adding acetazolamide to intravenous loop diuretics decreases congestion in patients with acute decompensated heart failure

New advice aims to reduce the cardiac side effects of cancer treatment

Study explores a potential new therapeutic approach for triple negative breast cancer treatment

Healthy people over 65 years of age recommended to get a heart check-up before non-cardiac surgery

New guidelines recommend earlier detection and treatment of pulmonary hypertension

Three-drug medication effective in preventing recurrent cardiovascular events after a heart attack

Heavy smoking and smoke inhalation linked to poor prognosis after a heart attack

Immune therapy may be an alternate therapeutic approach for treating chronic hepatitis B

New approach using CRISPR can engineer massive quantities of cells for therapeutic applications

What is the efficacy of Grignard Pure™ against surrogate of SARS-CoV-2?

What is the association between T lymphocyte-mediated immune responses and COVID-19 severity?

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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