Clinical Trial News and Research

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NYU Langone-led study to examine longer-term use of suppressive antiviral medication to reduce shingles

NYU Langone Medical Center will lead a five-year, 60-center clinical trial to evaluate new treatment protocols for herpes zoster ophthalmicus (HZO), a form of shingles that can seriously and permanently affect the eye.

17 Nov 2016

FDA approval of controversial drug for Duchenne muscular dystrophy raises concern and hope

In September, the Food and Drug Administration approved Exondys, a controversial treatment for Duchenne muscular dystrophy based on tenuous data from just 12 patients.

17 Nov 2016

High daily doses of vitamin D can help reduce incidence of ARI in older, long-term care residents

Researchers at the University of Colorado Anschutz Medical Campus have found that high doses of vitamin D reduce the incidence of acute respiratory illness (ARI) in older, long-term care residents.

16 Nov 2016

Crowdsourcing new prediction tool for better prognosis of metastatic castration-resistant prostate cancer

Knowing the likely course of cancer can influence treatment decisions. Now a new prediction model published today in Lancet Oncology offers a more accurate prognosis for a patient's metastatic castration-resistant prostate cancer.

16 Nov 2016

Study finds many parents agree to use of placebos in children

Placebos are essential in any controlled clinical trial, providing a yardstick against which the test drug is measured.

15 Nov 2016

Photoimmunotherapy may be promising treatment option to combat cancer

When Kerstin Stenson, MD, describes the innovative technique she is helping develop to fight cancer, it seems like she's describing a Tom Clancy military espionage novel.

15 Nov 2016

Experimental drug outperforms standard first-line therapy for advanced kidney cancer patients

An experimental kidney cancer drug outperformed the standard first-line therapy for patients with metastatic disease who are considered at risk for poorer than average outcomes, according to results of a randomized phase II clinical trial by researchers at Dana-Farber Cancer Institute.

15 Nov 2016

Novel approach combines imaging and electroanatomical mapping for targeted cardiac gene transfer

Gene therapy to repair damaged heart muscle is most likely to succeed if it can be injected at the site of ischemia where there is viable myocardium with reduced contractile ability, and a new technique that combines imaging and electroanatomical mapping does just that.

15 Nov 2016

Using the CLARITY Technique for Spinal Cord Rehabilitation and Repair

News-Medical speaks to Dr. Quentin Barraud about his work on spinal cord repair and how he uses the CLARITY technique in his research.

From Logos Biosystems 15 Nov 2016

Statins can help prevent first time heart attacks, strokes in adults with cardiovascular risk factors

Cholesterol-lowering drugs help prevent heart attacks and strokes in adults with cardiovascular risk factors such as high cholesterol, high blood pressure, diabetes and smoking, but have not yet had a heart attack or stroke, according to a large-scale analysis of clinical trial data led by the OHSU Pacific Northwest Evidence-Based Practice Center.

14 Nov 2016

New treatment strategy effective in preventing bleeding in AF patients who underwent PCI, study shows

A new study led by clinician-researchers at Beth Israel Deaconess Medical Center testing the safety and effectiveness of anticoagulant strategies for patients with atrial fibrillation who undergo stenting procedures has shown that therapies combining the anticoagulant drug rivaroxaban with either single or dual anti-platelet therapy were more effective in preventing bleeding complications than the current standard of care.

14 Nov 2016

Virginia Tech and CytImmune Sciences develop more effective and less toxic cancer treatment

Virginia Tech scientists have developed a new cancer drug that uses gold nanoparticles created by the biotech firm CytImmune Sciences to deliver paclitaxel — a commonly used chemotherapy drug directly to a tumor.

14 Nov 2016

Drug approved for other purposes can promote recovery from acute nerve damage, study shows

Researchers at the University of Rochester Medical Center believe they have identified a new means of enhancing the body's ability to repair its own cells, which they hope will lead to better diagnosis and treatment of traumatic nerve injuries, like those sustained in car accidents, sports injuries, or in combat.

14 Nov 2016

Study finds two differing medications to be safe and effective for preventing blood clots during PCI

Two differing blood clot prevention medications are just as safe and effective for patients undergoing percutaneous coronary intervention, a non-surgical procedure to open blood vessels narrowed by plaque buildup, according to a new study.

14 Nov 2016

New wearable medical device may reduce visceral fat, improve blood glucose in diabetes patients

Although effective for the treatment of diabetes, exercise is sometimes difficult for overweight or elderly people.

11 Nov 2016

Moffitt scientists show how mathematical modeling can predict patient responses to cancer drugs

Scientists have significantly improved their understanding of cancer and have developed numerous therapies that have helped to reduce patient mortality; however, the majority of drugs that make it to the clinical trial phase of development fail, despite promising data in laboratory studies.

11 Nov 2016

Researchers start enrolling patients for Phase II gene therapy trial for choroideremia

Following on from a successful world’s first Phase I gene therapy trial for choroideremia, Professor Robert MacLaren and his team at Oxford University and the Oxford Eye Hospital at the John Radcliffe Hospital have started a Phase II trial enrolling 30 patients.

11 Nov 2016

Allergan launches first and only oral contraceptive in softgel capsule for prevention of pregnancy

Allergan plc, a leading global pharmaceutical company, today announced the availability of TAYTULLA (norethindrone acetate and ethinyl estradiol capsules and ferrous fumarate capsules), 1mg/20mcg, the first and only oral contraceptive in a softgel capsule for the prevention of pregnancy

10 Nov 2016

Agendia partners with Cryogene and Mist to distribute breast cancer recurrence assay in the Middle East

Agendia, Inc., a world leader in personalized medicine and molecular cancer diagnostics, announced today a partnership agreement to distribute the company’s breast cancer recurrence assay, MammaPrint, in the Middle East.

10 Nov 2016

Researchers apply deep learning to modernize cancer surveillance

Despite steady progress in detection and treatment in recent decades, cancer remains the second leading cause of death in the United States, cutting short the lives of approximately 500,000 people each year.

10 Nov 2016

Clinical Trial News and Research

NYU Langone-led study to examine longer-term use of suppressive antiviral medication to reduce shingles

FDA approval of controversial drug for Duchenne muscular dystrophy raises concern and hope

High daily doses of vitamin D can help reduce incidence of ARI in older, long-term care residents

Crowdsourcing new prediction tool for better prognosis of metastatic castration-resistant prostate cancer

Study finds many parents agree to use of placebos in children

Photoimmunotherapy may be promising treatment option to combat cancer

Experimental drug outperforms standard first-line therapy for advanced kidney cancer patients

Novel approach combines imaging and electroanatomical mapping for targeted cardiac gene transfer

Using the CLARITY Technique for Spinal Cord Rehabilitation and Repair

Statins can help prevent first time heart attacks, strokes in adults with cardiovascular risk factors

New treatment strategy effective in preventing bleeding in AF patients who underwent PCI, study shows

Virginia Tech and CytImmune Sciences develop more effective and less toxic cancer treatment

Drug approved for other purposes can promote recovery from acute nerve damage, study shows

Study finds two differing medications to be safe and effective for preventing blood clots during PCI

New wearable medical device may reduce visceral fat, improve blood glucose in diabetes patients

Moffitt scientists show how mathematical modeling can predict patient responses to cancer drugs

Researchers start enrolling patients for Phase II gene therapy trial for choroideremia

Allergan launches first and only oral contraceptive in softgel capsule for prevention of pregnancy

Agendia partners with Cryogene and Mist to distribute breast cancer recurrence assay in the Middle East

Researchers apply deep learning to modernize cancer surveillance

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