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Mapping immune landscape of hematological malignancies may help improve cancer therapies

Activating the immune system of the body is a promising form of treatment for cancer. Researchers at the University of Helsinki and Helsinki University Hospital as well as the University of Eastern Finland mapped out the immune landscape of hematological malignancies in a dataset covering more than 10,000 patients to identify drug targets and patient groups which could potentially benefit from immunotherapies.

9 Jul 2020

New nanoconjugate blocks dissemination of tumor cells in animal models of acute myeloid leukemia

The nanoparticle targets only leukemic cells and therefore would reduce the severe adverse effects of current treatments.

9 Jul 2020

Study assesses the ability of a variety of mask materials

It's intuitive and scientifically shown that wearing a face covering can help reduce the spread of the novel coronavirus that causes COVID-19. But not all masks are created equal, according to new University of Arizona-led research.

9 Jul 2020

Experimental drug for rare ALS shows promise in early clinical trial

An experimental drug for a rare, inherited form of amyotrophic lateral sclerosis (ALS) has shown promise in a phase 1/phase 2 clinical trial conducted at Washington University School of Medicine in St. Louis, Massachusetts General Hospital in Boston and other sites around the world and sponsored by the pharmaceutical company Biogen Inc.

8 Jul 2020

UC Santa Cruz- led research center focuses on botanical natural products

Although millions of people take plant-based dietary supplements or herbal medicines, understanding the effects of these natural products on human health has proven to be extremely challenging.

8 Jul 2020

Fred Hutch joins new clinical trials network to fight COVID-19

Fred Hutchinson Cancer Research Center has been named the coordinating center for vaccine clinical trials of the COVID-19 Prevention Network.

8 Jul 2020

Cocktail of chemotherapy drugs may be safe, effective for patients with metastatic pancreatic cancer

Pancreatic cancer carries a poor prognosis, and it often goes undetected until advanced stages. A new BJS (British Journal of Surgery) study indicates that a certain cocktail of chemotherapy drugs may be a safe and effective treatment option for patients with a metastatic form of the disease.

8 Jul 2020

Analysis: How a COVID-19 vaccine could cost Americans dearly

Yes, of course, Americans' health is priceless, and reining in a deadly virus that has trashed the economy would be invaluable.

8 Jul 2020

World's first clinical trial of immune-boosting strategy to protect cancer patients from COVID-19

In the race to find new ways to prevent and treat COVID-19, Canadian researchers have launched an innovative clinical trial focussed on strengthening the immune system for one of the most vulnerable populations - cancer patients.

8 Jul 2020

New technology can rapidly disrupt existing biofilms that account for chronic diseases

Chronic and recurrent bacterial diseases are treatment-resistant due to the ability of the pathogens to establish biofilms, which act as fortresses built of extracellular DNA and proteins to protect populations of the bacteria.

8 Jul 2020

EPA approves Lysol products that kill SARS-CoV-2 on surfaces

The Environmental Protection Agency (EPA) just approved two disinfection sprays that can kill severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease (COVID-19), on surfaces.

8 Jul 2020

Asthma inhalers being trialed for treatment of COVID-19

Researchers from Queensland University of Technology and Oxford University are working in collaboration to begin human clinical trials of inhaled corticosteroids, commonly used for asthma patients, on patients with COVID-19. The researchers believe that this could be useful for patients with the novel coronavirus infection.

7 Jul 2020

Research shows probiotics can help combat anxiety and depression

Previous research has tied mental health issues and developmental disorders to gut health. Now, a team of British scientists has shown that foods that broaden the profile of helpful bacteria in the gut, which are collectively known as probiotics, can help ease anxiety and depression.

7 Jul 2020

Many in the UK would refuse a coronavirus vaccine, survey finds

The novel coronavirus pandemic (COVID-19) has left many scientists and pharmaceutical companies racing to develop an effective vaccine to combat the viral infection. With 21 candidate vaccines in clinical evaluation, 139 candidate vaccines in preclinical evaluation across the world, most countries are hoping to be first to the post.

7 Jul 2020

Researchers develop bioprinted skin model of cutaneous squamous cell carcinoma

The cover for issue 27 of Oncotarget features "Bimodal imaging examples of control and treated tumors (red) before and after the treatment period," by Browning, et al. and reported that the authors developed a 3-dimensional bioprinted skin model of cutaneous squamous cell carcinoma (cSCC) tumors together with a microscopy assay to test chemotherapeutic effects in tissue.

7 Jul 2020

NIH study: Long-acting form of HIV prevention drug more effective than daily oral pill

A pre-exposure prophylaxis (PrEP) regimen containing an investigational long-acting form of the HIV drug cabotegravir injected once every 8 weeks was more effective than daily oral Truvada at preventing HIV acquisition among cisgender men who have sex with men and transgender women who have sex with men in a clinical trial sponsored by the National Institutes of Health.

7 Jul 2020

Efficacy News and Research

Mapping immune landscape of hematological malignancies may help improve cancer therapies

New nanoconjugate blocks dissemination of tumor cells in animal models of acute myeloid leukemia

Study assesses the ability of a variety of mask materials

Experimental drug for rare ALS shows promise in early clinical trial

UC Santa Cruz- led research center focuses on botanical natural products

Fred Hutch joins new clinical trials network to fight COVID-19

Cocktail of chemotherapy drugs may be safe, effective for patients with metastatic pancreatic cancer

Analysis: How a COVID-19 vaccine could cost Americans dearly

World's first clinical trial of immune-boosting strategy to protect cancer patients from COVID-19

New technology can rapidly disrupt existing biofilms that account for chronic diseases

EPA approves Lysol products that kill SARS-CoV-2 on surfaces

Asthma inhalers being trialed for treatment of COVID-19

Research shows probiotics can help combat anxiety and depression

Many in the UK would refuse a coronavirus vaccine, survey finds

Researchers develop bioprinted skin model of cutaneous squamous cell carcinoma

NIH study: Long-acting form of HIV prevention drug more effective than daily oral pill

DNA resection pathways are highly specific, shows study

Dutch trial of convalescent plasma in COVID-19 discontinued

COVID-19 complications may be associated with von Willebrand factor in the blood

Novel cell-based approach used to reverse age-related impairments in animal model

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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