Protein C News and Research

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Researchers develop a modular software system for optimizing biological systems

Machine learning is transforming all areas of biological science and industry, but is typically limited to a few users and scenarios.

8 Jul 2022

Moffitt researchers discover kidney cancer-specific splicing variant biomarkers

Kidney cancer accounts for only 4% of all cancers in the United States; however, its incidence has more than doubled since 1975, with the most common type being clear cell renal cell carcinoma.

8 Jul 2022

Moffitt researchers discover how YAP1 protein contributes to angiogenesis in cancers

The formation of new blood vessels, also known as angiogenesis, is critical to the development and progression of cancer.

8 Jul 2022

Study offers a new understanding of the evolutionary diversification of KNL2 gene

In living organisms cells divide and reproduce in two ways, mitosis and meiosis. Mitosis results in two identical daughter cells, whereas meiosis results in four sex cells.

8 Jul 2022

Study finds microglia to be responsible for neuronal death in a mitochondrial disease animal model

Microglia, a type of central nervous system cell, is primarily responsible for neuronal death in Leigh Syndrome and the neurological symptoms related to this mitochondrial disease.

8 Jul 2022

Study shows how tau protein, critical to Alzheimer's, turns from normal to diseased state

Alzheimer’s disease, the most common form of dementia, currently has no cure or effective therapy, in part due to gaps in our understanding of how the progressive neurodegenerative disorder arises in the brain.

8 Jul 2022

Disrupting genes in the yeast Pichia pastori to increase its secretory production of useful proteins

A collaboration including researchers from Kobe University, University of Tokyo and Tohoku University has successfully identified and disrupted genes in the yeast Pichia pastoris (1) in order to increase its secretory production of useful proteins (2).

8 Jul 2022

Characterization of longer-term effects on behavior and brain inflammation following recovery from mild COVID-19

A recent study reported that long COVID in mice causes brain inflammation and cognitive impairment.

8 Jul 2022

The replicative ability and pathogenicity of Omicron BA.4 and BA.5 isolates in hamsters

Researchers characterized the clinical isolates of SARS-CoV-2 Omicron BA.4 and BA.5.

8 Jul 2022

Study suggests spironolactone may improve clinical outcomes in COVID-19

Researchers performed an integrative analysis of clinical outcomes and viral entry networks in severe COVID-19 infection.

8 Jul 2022

Immunogenicity and safety of the protein-based heterodimer booster vaccine for COVID-19

Researchers compared the immunogenicity and safety of the protein-based heterodimer vaccine (PHH-1V) and BNT162b2 COVID-19 vaccines.

8 Jul 2022

The strength and breadth of antibody responses elicited by hybrid immunity to COVID-19 vaccination or infection alone

Researchers assessed neutralizing antibody responses to SARS-CoV-2 after receiving one dose of vaccine.

8 Jul 2022

Rare Cells Capable of Transforming into Leukemia may Provide new Insight into Leukemic Landscape

In our latest interview, News Medical speaks to Adam G. Schrum, PhD, Associate Professor of Molecular Microbiology & Immunology and Surgery at the University of Missouri, about how dysfunction in an unusual type of thymocyte cell may develop into leukemia in some patients.

8 Jul 2022

Nanoparticle vaccine could protect against animal viruses including future SARS-CoV-2 variants

A recent study published in the Science journal depicted that mosaic receptor-binding domain (RBD) nanoparticles immunize from diverse sarbecovirus challenges, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), among animal models.

8 Jul 2022

Discovery of multiple new SARS-CoV-2 MPro inhibitors

In a recent study posted to the bioRxiv* preprint server, researchers performed an extensive library docking for new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro) covalent and non-covalent inhibitors.

8 Jul 2022

Diabetes not strongly associated with in-hospital COVID mortality

In a recent study posted to the medRxiv* preprint server, researchers assessed the association between diabetes mellitus (type 2 diabetes) and mortality among patients hospitalized with coronavirus disease 2019 (COVID-19) at multiple centers in Canada and Denmark.

8 Jul 2022

Antibodies transmitted through breast milk persist six months after COVID mRNA vaccination

Researchers describe the effects of COVID-19 vaccines in lactating mothers and relates their antibody response to the protection of their children.

7 Jul 2022

After 3 doses of COVID vaccine, most cancer patients retain detectable humoral immunity

In a recent study posted to the medRxiv* preprint server, researchers assessed the efficacy and durability of immune responses to the third dose of coronavirus disease 2019 (COVID-19) vaccines. They also assessed the efficacy of the fourth vaccine dose among severely immunocompromised patients with hematological malignancies.

7 Jul 2022

Scientists identify molecules promoting plant immunity

Two studies published by researchers at the Max Planck Institute for Plant Breeding Research in Cologne, Germany in collaboration with colleagues in China have discovered natural cellular molecules that drive critical plant immune responses.

7 Jul 2022

Researchers unravel mechanism that underlies failure of staph vaccine trials

For the most part, the bacterium Staphylococcus aureus is common and harmless, posing no threat to humans with whom they coexist.

7 Jul 2022

Protein C News and Research

Researchers develop a modular software system for optimizing biological systems

Moffitt researchers discover kidney cancer-specific splicing variant biomarkers

Moffitt researchers discover how YAP1 protein contributes to angiogenesis in cancers

Study offers a new understanding of the evolutionary diversification of KNL2 gene

Study finds microglia to be responsible for neuronal death in a mitochondrial disease animal model

Study shows how tau protein, critical to Alzheimer's, turns from normal to diseased state

Disrupting genes in the yeast Pichia pastori to increase its secretory production of useful proteins

Characterization of longer-term effects on behavior and brain inflammation following recovery from mild COVID-19

The replicative ability and pathogenicity of Omicron BA.4 and BA.5 isolates in hamsters

Study suggests spironolactone may improve clinical outcomes in COVID-19

Immunogenicity and safety of the protein-based heterodimer booster vaccine for COVID-19

The strength and breadth of antibody responses elicited by hybrid immunity to COVID-19 vaccination or infection alone

Rare Cells Capable of Transforming into Leukemia may Provide new Insight into Leukemic Landscape

Nanoparticle vaccine could protect against animal viruses including future SARS-CoV-2 variants

Discovery of multiple new SARS-CoV-2 MPro inhibitors

Diabetes not strongly associated with in-hospital COVID mortality

Antibodies transmitted through breast milk persist six months after COVID mRNA vaccination

After 3 doses of COVID vaccine, most cancer patients retain detectable humoral immunity

Scientists identify molecules promoting plant immunity

Researchers unravel mechanism that underlies failure of staph vaccine trials

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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