B Cell News and Research

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AI used to build a 3D model of the Commander complex

University of Queensland researchers have used artificial intelligence to build a 3D map of key cell components to better understand dementia and infectious diseases including COVID-19.

11 May 2023

Extracellular chaperones mediate the lysosomal degradation of misfolded proteins

When exposed to stressful conditions, several proteins tend to misfold and form aggregates inside or outside cells.

11 May 2023

Targeting the hemoglobin problem in sickle cell disease using a new drug

A class of drugs used for their ability to stop tumor cells from dividing is now under study for their potential to reduce the pain and damage caused by sickle cell disease, investigators report.

11 May 2023

High-fat diets can promote atherosclerosis via gut bacteria interactions with the immune system

In a recent study, researchers determined that derivatives of natural emulsifiers such as phospholipids found in high-fat, high-cholesterol diets can promote atherosclerosis via gut bacteria interactions with the immune system.

11 May 2023

New CRISPR genome-editing technology helps scientists to explore many cancer-linked mutations

Genomic studies of cancer patients have revealed thousands of mutations linked to tumor development.

11 May 2023

Exposure to traffic-related air pollution leads to memory loss and cognitive decline

Researchers from the University of California, Irvine have found that exposure to traffic-related air pollution in Irvine led to memory loss and cognitive decline and triggered neurological pathways associated with the onset of Alzheimer's disease.

11 May 2023

Fatty liver promotes the spread of colorectal cancer to the liver

Investigators at Cedars-Sinai Cancer found that fatty liver, a condition closely associated with obesity, promotes the spread of colorectal cancer to the liver.

11 May 2023

Targeting uncontrolled inflammation may make tumors more responsive to treatment

Van Andel Institute scientists have pinpointed how a specific gene mutation triggers an inflammatory cascade that may drive development of treatment-resistant cancers.

11 May 2023

Brain cancer cells use mitochondria from the central nervous system to grow into aggressive tumors

Glioblastoma cancer cells use mitochondria from the central nervous system to grow and form more aggressive tumors, according to new Cleveland Clinic-led findings published in Nature Cancer.

11 May 2023

Research sheds light on the early cellular events that give rise to pancreatic cancer

Discussions of cancer often stress the genetic mutations that drive disease by altering the normal function of cellular proteins.

11 May 2023

Scarring to the collagen framework causes dysfunction in Duchenne muscular dystrophy

Muscles that ache after a hard workout usually don't hurt for long, thanks to stem cells that rush to the injured site along "collagen highways" within the muscle and repair the damaged tissue.

11 May 2023

New NIH program seeks to discover and catalog the breadth of somatic mosaicism in human tissues

The National Institutes of Health is launching a new program, the Common Fund's Somatic Mosaicism Across Human Tissues Network, that aims to transform our knowledge of how much genetic variation there is in the cells and tissues throughout our bodies.

11 May 2023

Cellular Origins partners with ScaleReady to simplify, standardise, and automate cell therapy manufacturing

Cellular Origins a TTP Company focused on enabling scalable, cost-effective, and efficient manufacture of cell and gene therapies (CGTs).

From Cellular Origins 11 May 2023

Unlocking the secrets of Omicron: study reveals how unique spike mutations enable enhanced infectivity and resistance to immune barrier

Researchers reported the increased transmissibility of the severe acute respiratory syndrome coronavirus 2.

11 May 2023

ELRIG UK appoints Nick Clare to board as Vendor Strategy Work Group Lead

The European Laboratory Research & Innovation Group (ELRIG) UK today announced the appointment of Nick Clare to the ELRIG board. He will chair and lead the Vendor Strategy Work Group to help ensure the vendors’ perspectives and interests are represented within the ELRIG board.

From ELRIG (UK) Ltd. 11 May 2023

Analyzing impact of phospholipase D on the host immune response to A. fumigatus infection

Announcing a new article publication for Zoonoses journal. Aspergillus fumigatus infection in the lungs is accompanied by the recruitment of innate immune cells, phagocytosis, and the release of inflammatory factors.

11 May 2023

Researchers show the effect of SARS-CoV-2 infection on somatosensory abnormalities in a hamster model

In a recent article published in the journal Science Immunology, researchers in the United States performed a longitudinal cohort study in a golden hamster model to investigate the sensory-altering mechanisms induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection compared to an influenza A virus (IAV).

11 May 2023

B Cell News and Research

AI used to build a 3D model of the Commander complex

Extracellular chaperones mediate the lysosomal degradation of misfolded proteins

Targeting the hemoglobin problem in sickle cell disease using a new drug

High-fat diets can promote atherosclerosis via gut bacteria interactions with the immune system

New CRISPR genome-editing technology helps scientists to explore many cancer-linked mutations

Exposure to traffic-related air pollution leads to memory loss and cognitive decline

Fatty liver promotes the spread of colorectal cancer to the liver

Targeting uncontrolled inflammation may make tumors more responsive to treatment

Brain cancer cells use mitochondria from the central nervous system to grow into aggressive tumors

Research sheds light on the early cellular events that give rise to pancreatic cancer

Scarring to the collagen framework causes dysfunction in Duchenne muscular dystrophy

New NIH program seeks to discover and catalog the breadth of somatic mosaicism in human tissues

Cellular Origins partners with ScaleReady to simplify, standardise, and automate cell therapy manufacturing

Unlocking the secrets of Omicron: study reveals how unique spike mutations enable enhanced infectivity and resistance to immune barrier

ELRIG UK appoints Nick Clare to board as Vendor Strategy Work Group Lead

Analyzing impact of phospholipase D on the host immune response to A. fumigatus infection

Researchers show the effect of SARS-CoV-2 infection on somatosensory abnormalities in a hamster model

'Normal looking' skin may still carry sun-damaged DNA mutations that can trigger cancer

Researchers advance the understanding of sperm maturation

Protein inhibition could offer new strategies for treating severe asthma

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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