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Buck Institute research provides method to study sarcopenia

Our epigenome is a set of chemical switches that turn parts of our genome off and on at strategic times and locations. These switches help alter the way our cells act and are impacted by environmental factors including diet, exercise and stress. Research at the Buck Institute reveals that aging also effects the epigenome in human skeletal muscle. The study, appearing on line in Aging Cell, provides a method to study sarcopenia, the degenerative loss of muscle mass that begins in middle age.

21 Nov 2013

Loyola sports medicine surgeon offers tips to reduce risk of Turkey Bowl injuries

Every year around this time, Loyola University Medical Center sports medicine surgeon Dr. Pietro Tonino sees a spike in sprains, contusions, broken bones and other injuries suffered in Thanksgiving pick-up football games.

21 Nov 2013

BioCardia reports positive results for Transendocardial Autologous Cells in Ischemic Heart Failure Trial

BioCardia, Inc., a leader in cardiovascular regenerative medicine, today announced positive 12-month results for the randomized Transendocardial Autologous Cells (MSC or BMC) in Ischemic Heart Failure Trial (TAC-HFT).

20 Nov 2013

Mount Sinai researchers win Best Manuscript Award for research on repair, reversal of heart attack damage

The Editors of the American Heart Association's (AHA) journal Circulation Research have awarded Icahn School of Medicine at Mount Sinai researchers a "Best Manuscript Award" for their investigations on repair and reversal of heart attack damage.

20 Nov 2013

Tasquinimod drug effective for men with metastatic castration-resistant prostate cancer

An investigational prostate cancer treatment slows the disease's progression and may increase survival, especially among men whose cancer has spread to the bones, according an analysis led by the Duke Cancer Institute.

20 Nov 2013

Researchers identify new way to improve heart repair

Researchers from the Baylor College of Medicine and the Texas Heart Institute have discovered a new way to dramatically improve heart repair. The future goal is to use this knowledge to combat human cardiovascular disease by improving repair after a heart attack. The research has just been published in the scientific journal Development.

20 Nov 2013

UCP1 protein helps fight against obesity

The uncoupling Protein 1 (UCP1) is found exclusively in brown adipose tissue. Until some years ago it was thought that only babies and hibernating animals had brown adipose tissue, but since then it also has been found in adults, so UCP1 could be useful in the fight against obesity.

20 Nov 2013

Heart failure patients receiving LVAD may benefit from injection of powerful cells directly into heart

A multicenter team of researchers within the NIH-funded Cardiothoracic Surgical Trials Network, led by Icahn School of Medicine at Mount Sinai, have found end-stage heart failure patients who receive a surgically implanted left ventricular assist device heart pump may also benefit from a single dose of millions of powerful cells injected directly into their heart during surgery.

19 Nov 2013

Boston Scientific gets CE Mark approval for Vercise Deep Brain Stimulation System

The Boston Scientific Corporation Vercise Deep Brain Stimulation System has received CE Mark approval for the treatment of intractable primary and secondary dystonia, a neurological movement disorder characterized by involuntary muscle contractions.

19 Nov 2013

Philipp E. Scherer honored with 15th Naomi Berrie Award for Outstanding Research in Diabetes

Columbia University Medical Center has honored Philipp E. Scherer, PhD, with the 15th Naomi Berrie Award for Outstanding Research in Diabetes, for his work that helped usher in a new understanding of fat and its role in diabetes and other metabolic diseases. His discovery of adiponectin, a hormone produced by fat, helped transform the scientific concept of fat as an inert storage depot to one of it as an endocrine "organ" that exerts control over the brain, muscles, and other organs. The award, given annually by CUMC's Naomi Berrie Diabetes Center, is Columbia's top honor for excellence in diabetes research.

19 Nov 2013

Study explains why men's noses are bigger than women's

Human noses come in all shapes and sizes. But one feature seems to hold true: Men's noses are bigger than women's.

19 Nov 2013

Young adults who had childhood cancer more likely to be frail than their peers

Young adults who survived childhood cancer are more likely than their peers to be frail, according to a St. Jude Children's Research Hospital study, which reported the condition is more common among female survivors than women decades older. The research appears in the November 18 online edition of the Journal of Clinical Oncology.

18 Nov 2013

Researchers create new hybrid heart valve that remains strong, durable throughout the tests

A hybrid heart valve created from thin and highly elastic mesh embedded within layers of human cells was strong and durable in a study presented at the American Heart Association's Scientific Sessions 2013.

18 Nov 2013

Scientists reveal surprising role for HDAC1 proteins in development of skin tumors

Findings by scientists from the Max F. Perutz Laboratories (MFPL) of the University of Vienna and the Medical University of Vienna reveal a surprising role for histone deacetylase 1 (HDAC1) - a member of a family of chromatin modifying proteins - in the development of skin tumors.

18 Nov 2013

Researchers explore how certain molecular signaling pathways control aging across all species

Fruit flies are notoriously short-lived but scientists interested in the biology of aging in all animals have begun to understand why some fruit flies live longer than others. They have documented a direct association between insulin and life span, for example, and have observed a tradeoff between prolific reproduction and longevity. A new study, which may have broad implications across species, ties those findings more closely together by tracing an insulin signaling cascade through to protein quality control in muscle tissue and shortened life span.

18 Nov 2013

Heart disease: The leading cause of deaths related to pregnancy in California

Heart disease is the leading cause of women's pregnancy-related deaths in California - but nearly one-third could be prevented, according to research presented at the American Heart Association's Scientific Sessions 2013.

18 Nov 2013

Researchers develop novel system to image worm brain activity

A research team at Worcester Polytechnic Institute and The Rockefeller University in New York has developed a novel system to image brain activity in multiple awake and unconstrained worms. The technology, which makes it possible to study the genetics and neural circuitry associated with animal behavior, can also be used as a high-throughput screening tool for drug development targeting autism, anxiety, depression, schizophrenia, and other brain disorders.

18 Nov 2013

Researchers update promising strategies and therapies to restore skeletal muscle health

The progressive loss of skeletal muscle during aging, known as sarcopenia, underlies limitations in physical function and mobility, which in turn lead to falls, loss of independence, institutionalization and even death.

16 Nov 2013

Research shows superiority of whey protein

As science continues to support the role of protein in building and maintaining lean muscle, maintaining weight and aging healthy, consumers are embracing the important role of protein in the diet. But not all proteins are created equal and it turns out that protein quality really does matter.

16 Nov 2013

Human Treg responses allow sustained recombinant adeno-associated virus-mediated transgene expression

Successful gene therapy is based on the effective delivery and maintained expression of healthy copies of a gene into tissues of individuals with a disease-associated genetic mutation.

16 Nov 2013

Muscle News and Research

Buck Institute research provides method to study sarcopenia

Loyola sports medicine surgeon offers tips to reduce risk of Turkey Bowl injuries

BioCardia reports positive results for Transendocardial Autologous Cells in Ischemic Heart Failure Trial

Mount Sinai researchers win Best Manuscript Award for research on repair, reversal of heart attack damage

Tasquinimod drug effective for men with metastatic castration-resistant prostate cancer

Researchers identify new way to improve heart repair

UCP1 protein helps fight against obesity

Heart failure patients receiving LVAD may benefit from injection of powerful cells directly into heart

Boston Scientific gets CE Mark approval for Vercise Deep Brain Stimulation System

Philipp E. Scherer honored with 15th Naomi Berrie Award for Outstanding Research in Diabetes

Study explains why men's noses are bigger than women's

Young adults who had childhood cancer more likely to be frail than their peers

Researchers create new hybrid heart valve that remains strong, durable throughout the tests

Scientists reveal surprising role for HDAC1 proteins in development of skin tumors

Researchers explore how certain molecular signaling pathways control aging across all species

Heart disease: The leading cause of deaths related to pregnancy in California

Researchers develop novel system to image worm brain activity

Researchers update promising strategies and therapies to restore skeletal muscle health

Research shows superiority of whey protein

Human Treg responses allow sustained recombinant adeno-associated virus-mediated transgene expression

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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