Receptor News and Research

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Scientists reverse social traits associated with autism in mouse model

Research has been ongoing in the field of genetic mutations and changes and brain and other neural disorders including Autism Spectrum Disorders (ASD) and a new study in mice models of autism has shown a possible link between mutations or deletions of the SHANK3 gene and a rare disorder called Phelan-McDermid syndrome and ASD.

29 Jul 2019

Researchers demonstrate positive and negative role of LRH-1 during inflammation

Immune cells prevent bacteria, parasites or viruses from entering the body when, for example, the intestinal epithelium is injured.

26 Jul 2019

Maternal behavior in mice linked to oxytocin-sensitive cells in the female brain

A startling new study shows that cells that are exquisitely sensitive to oxytocin are found in a tiny region in the brains of female but not male mice. This could be of great importance in explaining maternal behavior in females and eventually in treating social disorders like postpartum depression and autism spectrum disorder.

25 Jul 2019

Scientists uncover how airborne particles can exaggerate airway inflammation

An international team of scientists have observed a previously unclear inflammatory mechanism caused by airborne particles that can worsen asthma symptoms, it has been reported in Toxicological Sciences.

25 Jul 2019

Study identifies new mechanism that impacts HIV infection

A team of scientists led by Texas Biomed's Assistant Professor Smita Kulkarni, Ph.D. and Mary Carrington, Ph.D., at the Frederick National Laboratory for Cancer Research, published results of a study that pinpointed a long noncoding RNA molecule which influences a key receptor involved in HIV infection and progression of the disease.

25 Jul 2019

New vaccine shows promise against toughest HIV strains

A new study reports successful immunization against a so-far invincible “death star” strain of an HIV-related laboratory virus (SIVmac239) and another tough strain. The new approach also achieves long-term protection with a single dose, showing that gene therapy could allow broad and durable protection, based on a modified form of the CD4 protein that allows HIV entry into human cells.

24 Jul 2019

CAR-T cells used to target glioblastoma

Immunotherapy is the new weapon against cancers and building upon existing research, a team of researchers from the Massachusetts General Hospital have devised a way to make immunotherapy more effective in a deadly and common form of brain cancer called glioblastoma.

24 Jul 2019

Fat cells may be egging on melanoma cells to become more aggressive

A new study has shown that fat cells could be implicated in the transformation of the melanoma cells in the skin into highly malignant cells that spread to the different organs of the body. A team from the Tel Aviv University, led by Prof. Carmit Levy and Dr. Tamar Golan of the Department of Human Genetics and Biochemistry at TAU's Sackler School of Medicine published their findings in the journal Science Signaling this week.

24 Jul 2019

Researchers identify cells required for formation of a functioning uterus

Knowledge of the biological processes involved in the development of the uterus is important for understanding uterine health and fertility.

24 Jul 2019

Folic acid supplementation mitigates risk of neural tube defects linked to HIV drug

Dolutegravir is a preferred medication for treating HIV infection, but it recently has been linked to a 6- to 9-fold increase in the risk for neural tube defects among babies born to mothers receiving the drug during early gestation.

24 Jul 2019

Women with breast cancer should start postoperative chemotherapy soon

Women with breast cancer should start postoperative chemotherapy, when recommended, ideally within four months of their cancer diagnosis because new study findings show that waiting longer is associated with poorer overall survival.

23 Jul 2019

High-resolution images offer clues to improve design of anti-nausea drugs

A new study using a special type of electron microscope using samples cooled to extremely cold temperatures provides critical information for drug developers seeking to reduce nausea and vomiting side effects of cancer treatments.

23 Jul 2019

Wild birds help shed light on stress resilience in humans

Stress is a common everyday experience, particularly in the world today. A new study might open the doors for the prevention and treatment of stress disorders, thanks to wild songbirds.

21 Jul 2019

Receptor in the uterus can detect sperm molecule, aids in sperm survival

Why does it take 200 million sperms to fertilize a single egg? The single sperm that reached the finished line has successfully survived multiple checkpoints within the female reproductive tract, dubbed as pre-fertilization events. Now, a new study shows that the uterus contains receptors that facilitate sperm survival.

19 Jul 2019

Low estrogen causes muscle loss in women after menopause

Pioneering research shows the essential role played by the female hormone estrogen in preserving muscle bulk and strength in women.

19 Jul 2019

Study reveals how aggressive prostate cancer metastasizes by evading the immune system

Researchers at The University of Texas MD Anderson Cancer Center have discovered how an aggressive form of prostate cancer called double-negative prostate cancer (DNPC) metastasizes by evading the the immune system.

18 Jul 2019

Study defines how diarrhea-causing rotavirus initially interacts with the host

Research by the Department of Microbiology of the University of Valencia, the Institute of Biomedicine of Valencia and the Institute of Agrochemistry and Food Technology of the CSIC has defined the initial interaction of human rotavirus P [8] (the main cause of gastroenteritis) with the recipients of the intestine.

18 Jul 2019

Human genotype determines if a given Alzheimer's drug will be effective

University at Buffalo researchers have determined that a human gene present in 75 % of the population is a key reason why a class of drugs for Alzheimer's disease seemed promising in animal studies only to fail in human studies.

18 Jul 2019

Gene modulation goes wireless hacking the "boss gene"

Researchers from the University at Buffalo have successfully used technology to wirelessly tweak the functioning of a gene FGFR1. This gene is vital in the growth of embryos into adults. Their experiments were successful in the lab grown brain tissues and shows potential in therapeutics.

16 Jul 2019

New method spots rare immune cells reactive against cancer

Researchers from the Garvan Institute of Medical Research have developed a new method to spot rare immune cells that are reactive against cancer cells, from within a patient's own immune system.

16 Jul 2019