Clinical Trial News and Research

RSS

RTI extends research support to improve treatment for pelvic floor disorders in women

RTI International will continue supporting research efforts to improve clinical care for women with pelvic floor disorders as part of the Pelvic Floor Disorders Network.

6 Oct 2016

Researchers uncover potential role of gut bacteria in neurodegeneration

Alzheimer's disease (AD), Parkinson's disease (PD) and Amyotrophic Lateral Sclerosis (ALS) are all characterized by clumped, misfolded proteins and inflammation in the brain. In more than 90 percent of cases, physicians and scientists do not know what causes these processes to occur.

6 Oct 2016

Treatment using PARP inhibitor shrinks tumors in breast cancer patients with BRCA mutations

All 13 newly diagnosed breast cancer patients with BRCA mutations had their tumors shrink significantly when treated with a PARP inhibitor ahead of frontline presurgical chemotherapy in a pilot study at The University of Texas MD Anderson Cancer Center.

5 Oct 2016

JAK inhibitors show promise in restoring hair growth in patients with alopecia areata

Seventy-five percent of patients with moderate to severe alopecia areata--an autoimmune disease that causes patchy, and less frequently, total hair loss--had significant hair regrowth after treatment with ruxolitinib, reported researchers from Columbia University Medical Center. By the end of their treatment, average hair regrowth was 92 percent.

5 Oct 2016

Rutgers researchers aim to set blood transfusion standards for heart attack patients

A Rutgers physician who has championed the movement to use less blood in transfusions has been awarded more than $16.1 million by the National Institutes of Health National Heart, Lung, and Blood Institute to lead a nation-wide clinical trial to evaluate whether a restrictive or a liberal blood transfusion is most beneficial to patients who have had a heart attack.

5 Oct 2016

Study evaluates outcomes of hypothermia treatment among patients with in-hospital cardiac arrest

In a study appearing in the October 4 issue of JAMA, Paul S. Chan, M.D., of Saint Luke's Mid America Heart Institute, Kansas City, and colleagues evaluated the association of hypothermia treatment with survival to hospital discharge and with favorable neurological survival at hospital discharge among patients with in-hospital cardiac arrest.

4 Oct 2016

Stanford scientists develop novel brain-sensing technology that allows typing at 12 words per minute

It does not take an infinite number of monkeys to type a passage of Shakespeare. Instead, it takes a single monkey equipped with brain-sensing technology - and a cheat sheet.

3 Oct 2016

GUMC receives FDA clearance to begin clinical study of cancer drug in patients with Alzheimer's disease

Georgetown University Medical Center today announces the U.S. Food and Drug Administration has completed its review of an investigational new drug application (IND) for the use of nilotinib in a phase II clinical trial for patients with mild to moderate Alzheimer's disease.

30 Sep 2016

ADDF awards $2.1 million grant for clinical study of cancer drug in Alzheimer's patients

The Alzheimer's Drug Discovery Foundation announces a $2.1 million grant awarded to R. Scott Turner, MD, PhD, of Georgetown University Medical Center to conduct a phase II clinical trial of low-dose nilotinib (marketed as Tasigna for use as a cancer therapy) in patients with Alzheimer's disease.

29 Sep 2016

Ki67 may help spare some breast cancer patients from sentinel lymph node biopsies

Breast cancer patients over 50 years old could be spared invasive procedures by use of stratification based on tumour size and molecular characteristics, including Ki67.

29 Sep 2016

FDA approves automated insulin delivery device for type 1 diabetes

The Food and Drug Administration (FDA) has approved a device that automatically monitors blood glucose levels and delivers insulin when appropriate, for people aged 14 years and older who have type 1 diabetes.

29 Sep 2016

UVA researchers begin first clinical trial using focused ultrasound to treat patients with epilepsy

Researchers at the University of Virginia are starting the first clinical trial in the world using focused ultrasound to treat patients with epilepsy.

29 Sep 2016

Researchers reveal how ultrasmall nanoparticles can kill cancer cells

Nanoparticles known as Cornell dots, or C dots, have shown great promise as a therapeutic tool in the detection and treatment of cancer.

29 Sep 2016

Additional antibiotic reduces infection rates by 50% for women who have cesarean delivery

Physicians at the University of Alabama at Birmingham and colleagues have discovered that administering the antibiotic azithromycin alongside the standard recommended antibiotic regimen, cefazolin, reduces infection rates by 50 percent for women who have a non-elective cesarean delivery.

28 Sep 2016

FDA approves Medtronic's ‘artificial pancreas’ for type 1 diabetes patients

The U.S. Food and Drug Administration today approved Medtronic's MiniMed 670G hybrid closed looped system, the first FDA-approved device that is intended to automatically monitor glucose (sugar) and provide appropriate basal insulin doses in people 14 years of age and older with type 1 diabetes.

28 Sep 2016

Penn researchers search twitter for tweets about cardiovascular disease

For years, marketers and other commercial data-miners have been using Twitter's vast database of "tweets" to gauge consumer attitudes and track events. Now medical researchers are getting in on the trend.

28 Sep 2016

Department of Defense funds cardiac cell therapy trial for heart failure patients

Building on the results of a recent Cedars-Sinai Heart Institute study published just six months ago, the Department of Defense has awarded a $10 million grant to fund a cardiac cell therapy trial for patients diagnosed with a common but difficult-to-treat form of heart failure.

28 Sep 2016

Experimental PET tracer can diagnose concussion-related brain degeneration in living person

An experimental positron emission tomography (PET) tracer can effectively diagnose concussion-related brain degeneration while a person is still alive, according to a proof-of-concept study conducted at the Icahn School of Medicine at Mount Sinai and published September 27 in the journal Translational Psychiatry.

27 Sep 2016

Clinical study to test efficacy of different formulations of flu vaccine in heart failure patients

Heart disease patients enrolled in a clinical trial - designed to test whether a stronger dose of the influenza vaccine can prevent death or hospitalization due to a heart attack, heart failure, stroke or pneumonia - have begun receiving their first flu shots in Toronto and Boston.

27 Sep 2016

Expectations of cancer patients may not match with actual results in phase I studies

In a study of cancer patients considering whether they should participate in phase I clinical trials, a high percentage were willing to participate after discussions with clinical staff, but nearly half thought that their tumors would shrink, which is much higher than what is realistically achieved.

27 Sep 2016

Clinical Trial News and Research

RTI extends research support to improve treatment for pelvic floor disorders in women

Researchers uncover potential role of gut bacteria in neurodegeneration

Treatment using PARP inhibitor shrinks tumors in breast cancer patients with BRCA mutations

JAK inhibitors show promise in restoring hair growth in patients with alopecia areata

Rutgers researchers aim to set blood transfusion standards for heart attack patients

Study evaluates outcomes of hypothermia treatment among patients with in-hospital cardiac arrest

Stanford scientists develop novel brain-sensing technology that allows typing at 12 words per minute

GUMC receives FDA clearance to begin clinical study of cancer drug in patients with Alzheimer's disease

ADDF awards $2.1 million grant for clinical study of cancer drug in Alzheimer's patients

Ki67 may help spare some breast cancer patients from sentinel lymph node biopsies

FDA approves automated insulin delivery device for type 1 diabetes

UVA researchers begin first clinical trial using focused ultrasound to treat patients with epilepsy

Researchers reveal how ultrasmall nanoparticles can kill cancer cells

Additional antibiotic reduces infection rates by 50% for women who have cesarean delivery

FDA approves Medtronic's ‘artificial pancreas’ for type 1 diabetes patients

Penn researchers search twitter for tweets about cardiovascular disease

Department of Defense funds cardiac cell therapy trial for heart failure patients

Experimental PET tracer can diagnose concussion-related brain degeneration in living person

Clinical study to test efficacy of different formulations of flu vaccine in heart failure patients

Expectations of cancer patients may not match with actual results in phase I studies

Event guide: 15th World Clinical Biomarkers & CDx Europe eBook

Latest eBooks

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Driving innovation in Korean drug development

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer