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Study: Dual-pronged strategy could successfully treat childhood cancer

A dual-pronged strategy using two experimental cancer drugs together could successfully treat a childhood cancer by inhibiting tumour growth and blocking off the escape routes it uses to become resistant to treatment, finds a new study.

3 Nov 2013

Scientists identify new toxic entity associated with dementia and motor neuron disease

A new toxic entity associated with genetically inherited forms of dementia and motor neuron disease has been identified by scientists at the UCL Institute of Neurology. The toxin is the result of a genetic mutation that leads to the production of RNA molecules which could be responsible for the diseases. The findings are published in the journal Acta Neuropathologica.

31 Oct 2013

Listeria's resistance to disinfectants

Recent years have seen significant outbreaks of listeriosis on both sides of the Atlantic. Although the disease can usually be treated successfully, it is occasionally fatal, most frequently in pregnant women or immunocompromized people.

31 Oct 2013

"Good" cholesterol improves blood glucose levels, say scientists

High density lipoprotein cholesterol (HDL), the so-called "good" cholesterol improves blood glucose levels by enhancing skeletal muscle function and reducing adiposity, scientists of the Helmholtz Zentrum München report in the current issue of the renown American Heart Association Journal ‚Circulation'.

31 Oct 2013

Risks of developing kidney failure, calcium deficiency from zoledronic acid are extremely rare

The risks of developing kidney failure and a calcium deficiency from the popular osteoporosis drug zoledronic acid are extremely rare, according to researchers at Loyola University Health System. These findings were presented earlier this month at the American Society for Bone and Mineral Research's annual meeting.

31 Oct 2013

Multidisciplinary team tests innovative heart failure therapy in global clinical trials

A multidisciplinary team of experts in heart failure, cardiac arrhythmia, and neurosurgery at The Mount Sinai Hospital are now testing nerve stimulation in the neck as a novel therapy for heart failure patients to potentially help relieve their debilitating symptoms of fatigue, shortness of breath, and heart arrhythmias, while reducing their hospitalizations.

30 Oct 2013

Brain-derived neurotrophic factor may inhibit glucose intolerance after cerebral ischemia

Interestingly, a recent study found that ischemic stress causes hyperglycemia and may worsen ischemic neuronal damage. In addition, decreased insulin sensitivity after ischemic stress seems to be involved in the development of post-ischemic glucose intolerance.

30 Oct 2013

Acacia Pharma begins APD403 Phase II study to prevent chemotherapy-induced nausea & vomiting

Acacia Pharma, a pharmaceutical company specialising in the development of drugs for supportive care, announces the initiation of a Phase II study of APD403 in the prevention of chemotherapy-induced nausea & vomiting (CINV).

30 Oct 2013

Mice exploit IRG proteins to create resistance mechanism against toxoplasma infection

One of the commonest parasites in the world is Toxoplasma gondii. Toxoplasma can infect most warm-blooded animals, including humans, and causes significant damage to the unborn child if a woman becomes infected for the first time during pregnancy.

30 Oct 2013

New headpiece can improve brain stimulation technique to treat depression

A brain stimulation technique that is used to treat tough cases of depression could be considerably improved with a new headpiece designed by University of Michigan engineers.

30 Oct 2013

Cytrx announces Q3 2013 financial results, provides clinical update

CytRx Corporation, a biopharmaceutical research and development company specializing in oncology, today reported financial results for the three and nine-month periods ended September 30, 2013, and provided a clinical update.

29 Oct 2013

Houston Methodist physicians provide tips for training, protecting the entire body

For avid runners, training for the next marathon never stops. While it's important to focus on running faster or farther, Houston Methodist physicians encourage runners to expand their training regimen and are providing the following tips for training and protecting the entire body.

29 Oct 2013

Phase 3 study shows STELARA inhibits structural damage in patients with active psoriatic arthritis

New findings from two integrated Phase 3 Janssen Research & Development, LLC (Janssen)-sponsored studies showed treatment with STELARA- (ustekinumab) resulted in significantly greater inhibition of structural damage in patients with active psoriatic arthritis compared with placebo.

29 Oct 2013

Study: Liposomal bupivacaine can provide longer-lasting nerve blocks

Can a new liposomal bupivacaine product provide long-lasting nerve block with a single injection? An initial study in humans shows promise-but also some "confusing results," reports the November issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society.

29 Oct 2013

Brief exposure to anabolic steroids may have long lasting performance-enhancing effects

Brief exposure to anabolic steroids may have long lasting, possibly permanent, performance-enhancing effects, shows a study published today [28 October] in The Journal of Physiology.

28 Oct 2013

Potential, low-cost approach to improve exercise adherence in knee osteoarthritis patients

New research presented at the American College of Rheumatology Annual Meeting in San Diego describes an exciting novel tool utilizing telephone linked technology that shows potential as a low cost approach to improving exercise adherence in patients with knee osteoarthritis.

28 Oct 2013

Rutgers scientists provide new information about rare genetic childhood disorder

Scientists at Rutgers University studying the cause of a rare childhood disease that leaves children unable to walk by adolescence say new findings may provide clues to understanding more common neurodegenerative diseases like Alzheimer's and Parkinson's and developing better tools to treat them.

28 Oct 2013

Scientists develop new drug to treat obstructive airway diseases

Scientists have developed a new drug (RPL554) that could treat obstructive airway diseases such as asthma and chronic obstructive pulmonary disease in two ways at once, according to new research published in The Lancet Respiratory Medicine.

25 Oct 2013

Researchers measure stiffness of ankle using "Anklebot" robot

For most healthy bipeds, the act of walking is seldom given a second thought: One foot follows the other, and the rest of the body falls in line, supported by a system of muscle, tendon, and bones.

25 Oct 2013

LCSB researchers publish current knowledge about the genetic, molecular causes of PD

Parkinson's disease continues to puzzle physicians and biologists alike - even though it is well-established that symptoms like muscle tremors, rigidity, and, during the final stages, immobility can all be traced back to the death of a certain type of brain cell called a dopaminergic neuron. The underlying cause of this cellular death is a complex web of interrelated genetic molecular processes as well as external factors, most of the details of which are well-known. But how the various factors correlate and influence each other continues to elude the scientific community.

24 Oct 2013

Muscle News and Research

Study: Dual-pronged strategy could successfully treat childhood cancer

Scientists identify new toxic entity associated with dementia and motor neuron disease

Listeria's resistance to disinfectants

"Good" cholesterol improves blood glucose levels, say scientists

Risks of developing kidney failure, calcium deficiency from zoledronic acid are extremely rare

Multidisciplinary team tests innovative heart failure therapy in global clinical trials

Brain-derived neurotrophic factor may inhibit glucose intolerance after cerebral ischemia

Acacia Pharma begins APD403 Phase II study to prevent chemotherapy-induced nausea & vomiting

Mice exploit IRG proteins to create resistance mechanism against toxoplasma infection

New headpiece can improve brain stimulation technique to treat depression

Cytrx announces Q3 2013 financial results, provides clinical update

Houston Methodist physicians provide tips for training, protecting the entire body

Phase 3 study shows STELARA inhibits structural damage in patients with active psoriatic arthritis

Study: Liposomal bupivacaine can provide longer-lasting nerve blocks

Brief exposure to anabolic steroids may have long lasting performance-enhancing effects

Potential, low-cost approach to improve exercise adherence in knee osteoarthritis patients

Rutgers scientists provide new information about rare genetic childhood disorder

Scientists develop new drug to treat obstructive airway diseases

Researchers measure stiffness of ankle using "Anklebot" robot

LCSB researchers publish current knowledge about the genetic, molecular causes of PD

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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