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Wrist-wearable devices more cost-effective than electrocardiograms and pulse palpation for atrial fibrillation screening

Screening individuals for atrial fibrillation (AF) using wearable devices is more cost-effective than screening using conventional methods such as 12-lead electrocardiogram (ECG) and pulse palpation, or than no screening at all, researchers from Massachusetts General Hospital (MGH) have found.

8 Aug 2022

Varenicline and cytisine not more efficacious than nicotine to treat risky drinking and smoking, study says

A clinical trial to test whether three proven smoking cessation treatments could also reduce alcohol intake found no differences between the medications, but the rates of behavior change for alcohol consumption and smoking were high in all treatment groups. Results suggest these medications could play an important role to reduce alcohol use and smoking at the same time. Unexpectedly, nicotine replacement therapy performed as well as the prescription drugs varenicline and cytisine.

8 Aug 2022

Nivolumab approved for combination with fluoropyrimidine- and platinum-based combination chemotherapy

Nivolumab has recently been approved both in combination with fluoropyrimidine- and platinum-based combination chemotherapy and in combination with ipilimumab for the first-line treatment of adults with unresectable advanced, recurrent or metastatic esophageal squamous cell carcinoma with PD-L1 expression of at least one percent. The German Institute for Quality and Efficiency in Health Care (IQWiG) now examined in two early benefit assessments whether these two combinations have an added benefit for patients in comparison with chemotherapy alone.

8 Aug 2022

Research suggests a new nanomedicine strategy for treatment of IBD patients

Inflammatory bowel disease (IBD), also known as "green cancer", is a chronic, non-specific disease of the intestine. IBD includes ulcerative colitis and Crohn's disease, both of which tend to be debilitating, lifelong conditions that can prove fatal in severe cases. Currently, there is no cure for IBD. The main clinical treatments are drugs such as aminosalicylic acid preparations and corticosteroids, but they are often accompanied by gastrointestinal problems, anemia, and various intestinal complications. Finding alternative, more effective options is a priority for researchers.

5 Aug 2022

Vitamin B12, folic acid supplements could potentially halt or reverse advanced form of fatty liver disease

Scientists at Duke-NUS Medical School in Singapore have uncovered a mechanism that leads to an advanced form of fatty liver disease - and it turns out that vitamin B12 and folic acid supplements could reverse this process.

5 Aug 2022

Combination of ultrasound and microbubbles helps medicines pass through the blood-brain barrier

Combining ultrasound and bubbles helps medicines pass through the protective blood-brain barrier and is giving hope for improved treatment of several diseases.

5 Aug 2022

Cognitive rehab may help older adults clear covid-related brain fog

Eight months after falling ill with covid-19, the 73-year-old woman couldn't remember what her husband had told her a few hours before. She would forget to remove laundry from the dryer at the end of the cycle. She would turn on the tap at a sink and walk away.

5 Aug 2022

What does the future look like for TB care?

In this interview, we speak to Charles Wells from Gates MRI about their current research into tuberculosis (TB) as well as the recent updated guidelines for TB care.

5 Aug 2022

Heart failure arises from mutations in distinct genes, study finds

Heart failure is a common and devastating disorder for which there is no cure. Many cardiomyopathies - conditions that make it difficult for the heart to pump blood such as dilated cardiomyopathy (DCM) and arrhythmogenic cardiomyopathy (ACM) - can lead to heart failure, but treatments for patients with heart failure do not take these distinct conditions into account.

5 Aug 2022

Researchers discover two signaling pathways that are downregulated in human hearts after birth

Published today in Stem Cell Reports, researchers from the University of Minnesota Medical School discovered two signaling pathways that are downregulated in human hearts after birth.

4 Aug 2022

Using native microbes as chassis for transgene delivery in live bacterial therapeutics

Residing within the human gut are trillions of bacteria and other microorganisms that can impact a variety of chronic human ailments, including obesity, type 2 diabetes, atherosclerosis, cancer, non-alcoholic fatty liver disease and inflammatory bowel disease.

4 Aug 2022

CHOP helps launch new computational platform to harmonize pediatric cancer data

Children's Hospital of Philadelphia has helped launch a new computational platform that will harmonize pediatric cancer data, allowing researchers, pharmaceutical companies, and advocacy groups to accelerate the pace of drug development for pediatric cancer.

4 Aug 2022

Therapy News and Research

Wrist-wearable devices more cost-effective than electrocardiograms and pulse palpation for atrial fibrillation screening

Varenicline and cytisine not more efficacious than nicotine to treat risky drinking and smoking, study says

Nivolumab approved for combination with fluoropyrimidine- and platinum-based combination chemotherapy

Research suggests a new nanomedicine strategy for treatment of IBD patients

Vitamin B12, folic acid supplements could potentially halt or reverse advanced form of fatty liver disease

Combination of ultrasound and microbubbles helps medicines pass through the blood-brain barrier

Cognitive rehab may help older adults clear covid-related brain fog

What does the future look like for TB care?

Heart failure arises from mutations in distinct genes, study finds

Researchers discover two signaling pathways that are downregulated in human hearts after birth

Using native microbes as chassis for transgene delivery in live bacterial therapeutics

CHOP helps launch new computational platform to harmonize pediatric cancer data

Fully reduced form of vitamin K found to efficiently inhibit ferroptotic cell death

Can high-dose coenzyme Q10 reduce the number and severity of post-COVID-19 condition-related symptoms?

Medical cannabis use may be common in women experiencing menopause-related symptoms

Genetic signatures may help predict immunotherapy response in patients with bladder cancer

'RNA fishing' technique identifies several proteins involved in the progression of melanoma

Cold exposure could make it harder for cancer cells to grow, mice study shows

Drugs with antiviral activity against monkeypox virus

Hemopurifier containing Galanthus nivalis resin removes SARS-CoV-2 variants

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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