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Chlamydiae need a lot of glutamine to multiply in human cells

If chlamydiae want to multiply in a human cell, the first thing they need is a lot of glutamine. Würzburg researchers have clarified how the pathogenic bacteria obtain this substance.

3 Aug 2020

Membrane protein regulates epigenetic plasticity by mediating iron endocytosis

CNRS researchers at the Institut Curie have recently shown that cancer cells use a membrane protein that has been known for several decades to internalise iron.

3 Aug 2020

Research explains recognized sex differences in COVID-19 outcomes

The COVID-19 pandemic has notably taken a more significant toll on men compared to women, in terms of both disease severity and death. Now, a new study by researchers at the Icahn School of Medicine at Mount Sinai and published on the preprint server medRxiv in August 2020 confirms the increased risk that males have for death following COVID-19 while also highlighting worse outcomes in women with coronary artery disease, obesity, and hypoxia compared to men.

3 Aug 2020

Oxford University and ZOE join forces to widen access to COVID-19 treatment trials

Oxford University and the COVID Symptom Study app are joining forces to widen access to two clinical trials of potential treatments for COVID-19.

3 Aug 2020

Immune system's oldest branches may underpin COVID severity

One of the immune system's oldest branches, called complement, may be influencing the severity of COVID disease, according to a new study from researchers at Columbia University Irving Medical Center.

3 Aug 2020

SARS-CoV-2 spike protein recognized by innate immune receptors in a glycan-dependent way

The spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) depends on its ability to infect new host cells following its replication and release from infected cells. This pivots on its ability to bind to cell surface receptors like the ACE2 enzyme.

3 Aug 2020

Severe fatigue common in COVID-19, independent of disease severity

Patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection often complain of fatigue, but now a new study shows that it also causes severe and frequent fatigue in those who recover after mild illness too.

2 Aug 2020

Researchers identify differences in clinical features of non-obese patients with NAFLD

Researchers from the University of Tsukuba identify differences in the clinical features of non-obese patients with non-alcoholic fatter liver disease based on their sex and body mass index.

2 Aug 2020

IRB Barcelona team receives ERC grant to develop new drugs against fibrosis

The team led by Manuel Serrano, ICREA researcher and Head of the Cellular Plasticity and Disease Lab at IRB Barcelona, has been awarded the Proof of Concept grant by the European Research Council.

31 Jul 2020

15 young scientists receive Damon Runyon Fellowship Award to pursue cancer research

Grants totaling nearly $3.5 million give early career investigators independence to pursue brave and bold cancer research.

31 Jul 2020

Study examines glucocorticoid tapering in rheumatoid arthritis

Is the long-term use of glucocorticoids essential in people with chronic inflammatory diseases such as rheumatoid arthritis, or can early discontinuation prevent characteristic side effects?

31 Jul 2020

Discovery could have important implications for brain infections, neurodegenerative diseases

More than 30 million Americans are infected with a brain parasite spread by cats and contaminated meat, but most will never show symptoms.

31 Jul 2020

New article reviews poor life expectancy associated with treatment-resistant schizophrenia

The vast majority of reviews on psychotropic drugs is focused on the potential benefits that may have. However, the vulnerabilities induced by treatment need also to be considered.

31 Jul 2020

Researchers report a liquid biopsy for COVID-19

A new study published on the preprint server medRxiv in July 2020 reports the potential of cell-free DNA as a marker of the severity of disease in COVID-19. This could help triage patients as well as provide a prognostic marker.

30 Jul 2020

Lab profiles differentiate MIS-C from severe COVID-19 in children

In the early days of the COVID-19 pandemic, the SARS-CoV-2 virus seemed only rarely to have serious complications in children.

30 Jul 2020

Multiple, intertwined cell death systems to prevent the spread of 'intracellular' bacteria

Melbourne researchers have revealed the multiple, intertwined cell death systems that prevent the spread of the 'intracellular' bacterium Salmonella, an important cause of typhoid fever which kills more than 100,000 people annually.

30 Jul 2020

Study shows how chronic psychological stress leads to sickle cell crises

A new study shows how chronic psychological stress leads to painful vessel-clogging episodes--the most common complication of sickle-cell disease (SCD) and a frequent cause of hospitalizations.

30 Jul 2020

First case report on pathologic findings of vasculitis of the small vessels in the heart

A team of LSU Health New Orleans pathologists published what is believed to be the first case report on pathologic findings of vasculitis of the small vessels of the heart, which likely represents multisystem inflammatory syndrome.

30 Jul 2020

A collaborative research project to detect biofilm causing pathogens within chronic infections

WOUND care experts at the University of Huddersfield have joined forces with industry to pool their expertise for a research project that aims to not only significantly improve quality of life for those suffering with chronic wound infections but also has the potential to save the global healthcare industry millions of pounds.

30 Jul 2020

Impact training improves bone and muscle health in people with Crohn’s disease

Research from Northumbria University, Newcastle, has shown the important role specific types of exercise can play in the management of bone loss, fatigue and muscle dysfunction for those with Crohn’s disease.

30 Jul 2020

Inflammation News and Research

Chlamydiae need a lot of glutamine to multiply in human cells

Membrane protein regulates epigenetic plasticity by mediating iron endocytosis

Research explains recognized sex differences in COVID-19 outcomes

Oxford University and ZOE join forces to widen access to COVID-19 treatment trials

Immune system's oldest branches may underpin COVID severity

SARS-CoV-2 spike protein recognized by innate immune receptors in a glycan-dependent way

Severe fatigue common in COVID-19, independent of disease severity

Researchers identify differences in clinical features of non-obese patients with NAFLD

IRB Barcelona team receives ERC grant to develop new drugs against fibrosis

15 young scientists receive Damon Runyon Fellowship Award to pursue cancer research

Study examines glucocorticoid tapering in rheumatoid arthritis

Discovery could have important implications for brain infections, neurodegenerative diseases

New article reviews poor life expectancy associated with treatment-resistant schizophrenia

Researchers report a liquid biopsy for COVID-19

Lab profiles differentiate MIS-C from severe COVID-19 in children

Multiple, intertwined cell death systems to prevent the spread of 'intracellular' bacteria

Study shows how chronic psychological stress leads to sickle cell crises

First case report on pathologic findings of vasculitis of the small vessels in the heart

A collaborative research project to detect biofilm causing pathogens within chronic infections

Impact training improves bone and muscle health in people with Crohn’s disease

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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