Bioinformatics News and Research

RSS

Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

New MOGONET outperforms existing supervised multi-omics integrative analysis approaches

Genomics, proteomics, metabolomics, transcriptomics -- rapid advances in high-throughput biomedical technologies has enabled the collection of data with unprecedented detail from the growing number of omics.

27 Aug 2021

Neuroinflammation is the key upstream mechanism in Alzheimer’s disease progression

Neuroinflammation is the key driver of the spread of pathologically misfolded proteins in the brain and causes cognitive impairment in patients with Alzheimer's disease, researchers from the University of Pittsburgh School of Medicine reveal in a paper published today in Nature Medicine.

26 Aug 2021

Dotmatics Appoints Michael Swartz as Senior Vice President Enterprise Product to Support Continued Rapid Growth

Dotmatics Ltd today announced it has appointed Michael Swartz to lead its Enterprise Product Strategy and Management functions.

From Dotmatics 24 Aug 2021

Study investigates the effects of calycosin on breast cancer cell progression

Aging-US published "Calycosin inhibits breast cancer cell migration and invasion by suppressing EMT via BATF/TGF-β1" which reported that in this study, the authors investigated the effects of calycosin on breast cancer cell progression and their underlying mechanisms. Calycosin dose- and time-dependently inhibited proliferation, migration, and invasion by T47D and MCF-7 breast cancer cells by downregulating basic leucine zipper ATF-like transcription factor expression.

23 Aug 2021

New PULSAR radiation-therapy strategy achieves better tumor control

Artificial intelligence, along with a $71-million expansion of Radiation Oncology services, is allowing UT Southwestern Medical Center cancer physicians to pioneer a new PULSAR radiation-therapy strategy that improves tumor control compared with traditional daily therapy.

From Elekta 20 Aug 2021

SARS-CoV-2 lambda variant escapes immune response via spike mutations

A new study explores the mechanism by which the SARS-CoV-2 lambda variant has acquired immune evasion capabilities above that of the wildtype.

20 Aug 2021

HMGA1 plays role in gastric cancer cell proliferation and metastasis

Aging-US published "HMGA1 promotes gastric cancer growth and metastasis by transactivating SUZ12 and CCDC43 expression" which reported that HMGA1 is overexpressed in GC cells and the high expression of HMGA1 was correlated with worse survival in GC patients using a bioinformatics assay.

19 Aug 2021

MD Anderson receives nearly $13 million from CPRIT to support research efforts

The University of Texas MD Anderson Cancer Center has been awarded $12.75 million from the Cancer Prevention and Research Institute of Texas to support basic, clinical, translational and prevention research efforts, including $3 million for a new project to build clinical trial network infrastructure across Texas.

19 Aug 2021

SARS-CoV-2 ORF8 and the expression of cytokine in human macrophages

A new study has determined the production of the SARS-CoV-2 SP-dependent ORF8.

18 Aug 2021

Study provides insight into fitness effects of genomic structural variants in natural populations

Molecular geneticists have known for about a decade that genomic structural variants can play important roles in the adaptation and speciation of both plants and animals, but their overall influence on the fitness of plant populations is poorly understood.

16 Aug 2021

Researchers assess the genetic features of T-cell immunity development to SARS-CoV-2 variants

The continuing emergence of new SARS-CoV-2 mutations allows the virus to spread more effectively and evade antibodies. However, it is unclear whether new strains are capable of evading T-cell immunity - one of the body's main lines of defense against COVID-19.

16 Aug 2021

Study finds four circulating miRNAs which could effectively inhibit SARS-CoV-2 replication

In a new study, Chen-Yu Zhang's group from Nanjing University presents a rather striking finding that four circulating miRNAs, which are high in healthy people and much lower in older people and diabetic patients, could effectively inhibit SARS-CoV-2 replication by directly targeting the S protein.

12 Aug 2021

Bioinformatics News and Research

Further Reading

New MOGONET outperforms existing supervised multi-omics integrative analysis approaches

Neuroinflammation is the key upstream mechanism in Alzheimer’s disease progression

Dotmatics Appoints Michael Swartz as Senior Vice President Enterprise Product to Support Continued Rapid Growth

Study investigates the effects of calycosin on breast cancer cell progression

New PULSAR radiation-therapy strategy achieves better tumor control

SARS-CoV-2 lambda variant escapes immune response via spike mutations

HMGA1 plays role in gastric cancer cell proliferation and metastasis

MD Anderson receives nearly $13 million from CPRIT to support research efforts

SARS-CoV-2 ORF8 and the expression of cytokine in human macrophages

Study provides insight into fitness effects of genomic structural variants in natural populations

Researchers assess the genetic features of T-cell immunity development to SARS-CoV-2 variants

Study finds four circulating miRNAs which could effectively inhibit SARS-CoV-2 replication

SARS-CoV-2 variants and their ability to infect mice

Study may provide a new therapeutic target for treatment of LUAD patients

Study uncovers link between corticosteroid receptors and ciliary, neuroplasticity genes in the brain

Research reveals a microRNA network as putative mediators of myocardial reductive stress

Experimental drug combination extends survival in mice with lung cancer, study finds

Researchers use AI to assess metastatic potential of melanoma cells

World's most sophisticated COVID-19 sequencing system

Research uncovers an unexpected role for immune T cells in protection against malaria

Lab Diagnostics and Automation - Third Edition eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo