Nitric Oxide News and Research

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NicOx signs agreement for commercial manufacture of Naproxcinod drug substance

NicOx S.A. (Euronext Paris: COX) has announced it has signed an agreement with the fine chemical company Archimica, for the commercial manufacturing and supply of naproxcinod drug substance (or active pharmaceutical ingredient, API).

20 Mar 2008

How diabetes drives atherosclerosis

Researchers have discovered how diabetes, by driving inflammation and slowing blood flow, dramatically accelerates atherosclerosis, according to research to be published in the March 14 edition of the journal Circulation Research. Experts once believed that atherosclerosis, or hardening of the arteries, developed when too much cholesterol clogged arteries with fatty deposits called plaques.

14 Mar 2008

Low dose inhaled corticosteroids improve lung function in mild asthma patients

A study by the Woolcock Institute of Medical Research in Sydney is the first to demonstrate that in patients with very mild or well-controlled asthma, regular treatment with low dose ICS leads to significantly better day-to-day lung function.

11 Mar 2008

Study aims to improve treatment for children born with heart defects

Trying to understand and stop the collateral lung damage that can occur in babies with congenital heart disease is the focus of a new study.

11 Mar 2008

Low-fat better than low-carb diets for heart health

Low-fat diets are more effective in preserving and promoting a healthy cardiovascular system than low-carbohydrate, Atkins'-like diets, according to a new study by researchers at the Medical College of Wisconsin in Milwaukee.

1 Mar 2008

Study identifies another strategy for normalizing tumor blood supply

Manipulating levels of nitric oxide (NO), a gas involved in many biological processes, may improve the disorganized network of blood vessels supplying tumors, potentially improving the effectiveness of radiation and chemotherapy.

21 Feb 2008

Optical tool detects biomarkers in breath

Exhale on a cold winter day and you will see the water vapor coming out of your mouth.

20 Feb 2008

Beetroot juice reduces blood pressure

Researchers at Barts and The London School of Medicine have discovered that drinking just 500ml of beetroot juice a day can significantly reduce blood pressure.

7 Feb 2008

Weakness found in anthrax bacterium

MIT and New York University researchers have identified a weakness in the defenses of the anthrax bacterium that could be exploited to produce new antibiotics.

25 Jan 2008

High blood pressure gene found

Scientists have identified the gene that sets off a sequence of events in the blood vessels of otherwise healthy adults that can lead to high blood pressure.

11 Jan 2008

NicOx extends ophthalmology agreement with Pfizer

NicOx S.A. has announced it has signed an extension of its March 2006 collaboration agreement, which grants Pfizer Inc the exclusive right to apply its proprietary nitric oxide-donating technology to drug discovery research in the field of ophthalmology.

9 Jan 2008

Children with high nitric oxide levels may still breathe easy

Nitric oxide (NO) is a gas released by cells in the lungs. When a person with allergies and/or asthma experiences an inflamed airway, the inflammatory cells release more NO and the NO levels increase. Due to this fact, fractional concentration of exhaled NO (FeNO) is an increasingly used tool in the diagnosis and management of asthma in children and adults.

7 Jan 2008

Polybrominated diphenyl ethers used as fire retardants could be harmful

Polybrominated diphenyl ethers (PBDEs), chemicals used as fire retardants, can be found in numerous items in the home, such as the television, computer, toaster and the sofa.

10 Dec 2007

Ikaria's INOmax approved in Australia

Ikaria Holdings, Inc., through its subsidiary INO Therapeutics LLC, announced today that it has received approval from Australia's regulatory body, the Therapeutic Goods Administration (TGA), for INOmax (nitric oxide) for inhalation.

27 Nov 2007

New drug called nitrosyl-cobinamide could potentially be used to treat hypertension and heart disease

Investigators at the University of California, San Diego School of Medicine have developed a new drug called nitrosyl-cobinamide.

27 Nov 2007

New discoveries about nitric oxide can provide drugs for schizophrenia

Problems with memory and social function in patients with schizophrenia may result from an imbalance in the brain’s nitric oxide system.

21 Nov 2007

Project aims to deepen the medical and research community's understanding of women's health

Women's bodies and medical needs are vastly different than men's way beyond their reproductive systems.

20 Nov 2007

Nitrite/nitrate-rich foods may help in heart attack survival

Nitrite/nitrate found in vegetables, cured meats and drinking water may help you survive a heart attack and recover quicker, according to a pre-clinical study led by a cardiovascular physiologist at The University of Texas Health Science Center at Houston.

13 Nov 2007

Diet rich in leafy vegetables may minimize damage caused by heart attacks

A diet rich in leafy vegetables may minimize the tissue damage caused by heart attacks, according to researchers at the Albert Einstein College of Medicine of Yeshiva University.

13 Nov 2007

Lungs' pressure needn't threaten heart transplant survival

Heart surgeons at Johns Hopkins say people who need heart transplants can largely avoid transplant failure due to elevated blood pressure in their lungs with the help of proper drug treatment.

6 Nov 2007