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Researchers explore immune responses to mpox infections

In new research, researchers demonstrated that individuals recovering from mpox virus (MPXV) infection have neutralizing antibodies that target MPXV antigens A35R and H3L.

17 Jan 2023

Preclinical study shows the therapeutic value of kinetin against SARS-CoV-2

Researchers investigated the ability of kinetin (N6-furfurylaminopurine, MB-905) to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proliferation in vitro.

17 Jan 2023

Study finds non-Omicron breakthrough infections elicit robust cross-neutralizing activity against Omicron variants across the antigenic barrier

Researchers assessed the effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection with a non-Omicron variant on SARS-CoV-2 BA.4/5 neutralization.

17 Jan 2023

New test 'fishes' for multiple respiratory viruses using DNA as 'bait'

A new test that 'fishes' for multiple respiratory viruses at once using single strands of DNA as 'bait', and gives highly accurate results in under an hour, has been developed by Cambridge researchers.

16 Jan 2023

Researchers report that vectored expression of a high-affinity ACE2 microbody protein establishes a high degree of protection from SARS-CoV-2

Researchers evaluated the use of receptor decoys for SARS-CoV-2 based on soluble forms of ACE2 for immunological prophylaxis and management of COVID-19 through the use of AAV vectors.

16 Jan 2023

Intranasal mRNA-lipid nanoparticle vaccines elicit significant protection against SARS-CoV-2 in hamsters

Researchers from the United States evaluated the efficacy and immunogenicity of an intranasal messenger ribonucleic acid (mRNA)-lipid nanoparticle (LNP) vaccine against SARS-CoV-2 using a hamster model.

16 Jan 2023

The long-term clinical outcomes of SARS-CoV-2 infection in people with mild disease in Israel

Researchers conducted a nationwide study in Israel to determine the post-acute sequelae of SARS-CoV-2 a year after mild COVID-19.

16 Jan 2023

What is the efficacy of the COVID-19 second booster versus the first booster with prior COVID-19 infections?

Researchers assessed the efficacy of the COVID-19 second booster vaccine compared to the first booster vaccine and the protection conferred by prior COVID-19 infection.

16 Jan 2023

Artemisia argyi plant extracts and phytochemicals shown to inhibit SARS-CoV-2 in new research

Researchers reported that Artemisia argyi extracts and phytochemicals could inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

16 Jan 2023

Study investigates the spectrum of antibody immunity across several SARS-CoV-2 variants

Researchers evaluated antibody responses to the spike proteins of the SARS-CoV-2 Wuhan-Hu-1 strain and VOCs such as the Alpha, Beta, Gamma, Delta, and Omicron.

16 Jan 2023

Researchers study bacterial co-infections and antibiotic use in COVID-19 patients

Researchers estimated the frequency of bacterial co-infections among hospitalized coronavirus disease 2019 (COVID-19) patients and of antibiotic prescriptions in the initial COVID-19 period for appraising the usage of antibiotic stewardship criteria.

13 Jan 2023

Discovery of a potential new target for new MPOX or broad pox vaccines

In a recent study posted to the medRxiv* preprint server, researchers in the United Kingdom developed a pooled enzyme-linked immunosorbent (ELISA) assay using mpox (MPX) virus (MPXV) antigens and vaccinia virus (VACV) antigens. They also assessed humoral responses to and identification of antigens of MPXV IIa clade and IIb clade, in comparison to recipients of smallpox vaccines (ACAM2000 and IMVANEX).

12 Jan 2023

Study on the ecology of viruses in urban rodents with special emphasis on SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, researchers investigated whether commensal rodent pests such as rats and mice, sourced from sewers and urban settings, are exposed to and are infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). They also investigated viruses present in commensal rodents.

12 Jan 2023

The 2022 U.S. RSV surge consisted of a variety of pre-existing viruses

In a recent study posted to the medRxiv* preprint server, researchers investigated whether the upsurge in respiratory syncytial virus (RSV) infections during the autumn season of 2022 occurred due to the emergence of a novel, highly transmissible RSV strain or whether multiple pre-existing RSV strains were responsible for the increase in RSV case counts during the period.

12 Jan 2023

COVID-19 booster doses could significantly reduce the incidence of SARS-CoV-2 infection among young adults

A recent study published in the journal PLOS Medicine examined the effectiveness of booster doses of coronavirus disease 2019 (COVID-19) vaccines in protecting vaccinated young adults against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections during the dominant period of the Omicron BA.1 variant.

12 Jan 2023

Study shows booster vaccinations against SARS-CoV-2 effective but protection wanes rapidly

A recent study posted to medRxiv* assessed the effectiveness of primary and booster vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the Netherlands.

11 Jan 2023

Green tea may protect against telomere shortening due to biological aging

A new study in Scientific Reports aimed to analyze the association between cross-section and longitudinal LTL changes with the consumption of soft drinks, coffee, and tea among middle-aged and older Korean men and women for six years. It also assessed any changes in the association results according to a difference in sex and age groups.

11 Jan 2023

COVID-19 outcomes in Rituximab treated patients

A new report throws light on SARS-CoV-2 breakthrough infections in patients with certain joint diseases or musculoskeletal conditions who are on rituximab and compares the severity of COVID-19 outcomes in these patients whilst identifying potential risk factors for severe outcomes.

11 Jan 2023

What is the association between acute lymphoblastic leukemia and congenital cytomegalovirus infection?

Researchers evaluated the relationship between congenital cytomegalovirus (cCMV) infection and acute lymphoblastic leukemia (ALL).

11 Jan 2023

The main source of editing of the mpox virus genome during the 2022 outbreak

Researchers investigated the main source of editing of the 2022 mpox virus genome.

11 Jan 2023

Polymerase News and Research

Researchers explore immune responses to mpox infections

Preclinical study shows the therapeutic value of kinetin against SARS-CoV-2

Study finds non-Omicron breakthrough infections elicit robust cross-neutralizing activity against Omicron variants across the antigenic barrier

New test 'fishes' for multiple respiratory viruses using DNA as 'bait'

Researchers report that vectored expression of a high-affinity ACE2 microbody protein establishes a high degree of protection from SARS-CoV-2

Intranasal mRNA-lipid nanoparticle vaccines elicit significant protection against SARS-CoV-2 in hamsters

The long-term clinical outcomes of SARS-CoV-2 infection in people with mild disease in Israel

What is the efficacy of the COVID-19 second booster versus the first booster with prior COVID-19 infections?

Artemisia argyi plant extracts and phytochemicals shown to inhibit SARS-CoV-2 in new research

Study investigates the spectrum of antibody immunity across several SARS-CoV-2 variants

Researchers study bacterial co-infections and antibiotic use in COVID-19 patients

Discovery of a potential new target for new MPOX or broad pox vaccines

Study on the ecology of viruses in urban rodents with special emphasis on SARS-CoV-2

The 2022 U.S. RSV surge consisted of a variety of pre-existing viruses

COVID-19 booster doses could significantly reduce the incidence of SARS-CoV-2 infection among young adults

Study shows booster vaccinations against SARS-CoV-2 effective but protection wanes rapidly

Green tea may protect against telomere shortening due to biological aging

COVID-19 outcomes in Rituximab treated patients

What is the association between acute lymphoblastic leukemia and congenital cytomegalovirus infection?

The main source of editing of the mpox virus genome during the 2022 outbreak

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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