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Mindfulness-based intervention leads to drop in blood pressure

Blood pressure is effectively lowered by mindfulness-based stress reduction for patients with borderline high blood pressure or "prehypertension." This finding is reported in the October issue of Psychosomatic Medicine: Journal of Biobehavioral Medicine, the official journal of the American Psychosomatic Society.

16 Oct 2013

Phase 3 ODYSSEY MONO trial with alirocumab meets primary efficacy endpoint

Sanofi and Regeneron Pharmaceuticals, Inc. today announced that the Phase 3 ODYSSEY MONO trial with alirocumab, an investigational monoclonal antibody targeting PCSK9 (proprotein convertase subtilisin/kexin type 9), met its primary efficacy endpoint.

16 Oct 2013

Senate leaders close in on deal that leaves health law intact

The agreement could include a one-year delay in the health law's reinsurance tax, as well as a measure to tighten income verification standards for qualifying for health insurance subsidies.

16 Oct 2013

UC researchers receive $2.1M grant from NIH to study molecular mechanisms of muscle fatigue

University of Cincinnati (UC) researchers have been awarded a five-year, $2.1 million grant from the National Institutes of Health (NIH) to study an isoform that plays a critical role in human resistance to fatigue.

16 Oct 2013

First Edition: October 15, 2013

Today's headlines include reports about how the budget deal taking shape in the Senate would not derail the health law, but would include some tweaks.

15 Oct 2013

Acacia Pharma reports positive results from APD515 Phase II study for treatment of xerostomia

Acacia Pharma, a pharmaceutical company specialising in the development of drugs for supportive care, announces positive results from its Phase II study of APD515 for the treatment of xerostomia (dry mouth) in advanced cancer patients.

15 Oct 2013

Researchers to present latest findings in emergency medicine research at ACEP13-Scientific Assembly

Leading researchers in emergency medicine will present more than 400 studies during ACEP13-Scientific Assembly, the annual meeting of the American College of Emergency Physicians in Seattle, Washington.

15 Oct 2013

American Heart Association recommends docs to evaluate patients’ physical activity habits

Doctors should evaluate your physical activity habits as routinely as checking your blood pressure and other risk factors for cardiovascular diseases, the American Heart Association recommends in a scientific statement published in its journal Circulation.

15 Oct 2013

Statins may increase risk of cataracts among individuals above 30 years old

According to the Centers for Disease Control and Prevention, cataracts are the number one cause of vision loss in the United States. Nearly 22 million Americans age 40 and over have cataracts, while more than half of individuals age 80 and over suffer from this condition. In a recent study released in JAMA Ophthalmology, it was confirmed that statins, which are typically prescribed to reduce cholesterol and also prevent heart disease, may cause an increased risk for cataracts among individuals ages 30 through 85.

14 Oct 2013

CNIO researchers perform first exome sequencing for non-infiltrating bladder cancer

Bladder cancer represents a serious public health problem in many countries, especially in Spain, where 11,200 new cases are recorded every year, one of the highest rates in the world. The majority of these tumours have a good prognosis -- 70-80% five-year survival after diagnosis -- and they do not infiltrate the bladder muscle at the time of diagnosis -- in around 80% of cases.

14 Oct 2013

Scientists discover genetic mutation associated with low-risk bladder cancer

An international research team led by scientists from Georgetown Lombardi Comprehensive Cancer Center has discovered a genetic mutation linked to low-risk bladder cancer.

13 Oct 2013

New approach could help identify specific gene mutations linked to increased disease risk

Researchers at the University of California, San Diego School of Medicine have developed a new way to parse and understand how special proteins called "master regulators" read the genome, and consequently turn genes on and off.

13 Oct 2013

Men who didn't exercise more likely to have dysfunctional HDL

There's no question that high levels of good cholesterol-also known as high-density lipoprotein -seem to be protective against heart disease. Rather than depositing fat into the blood vessels the way the "bad" cholesterol (low-density lipoprotein does, HDL appears to carry cholesterol away from blood vessels to the liver. From there, the liver processes it for removal from the body.

13 Oct 2013

Deficiency of antioxidant response protein prevents hypertrophic cardiomyopathy

University of Utah researchers have found that deficiency of an antioxidant response protein called nuclear erythroid-2 like factor-2 (Nrf2) delays or prevents hypertrophic cardiomyopathy, a type of a heart failure in which the heart muscle grows abnormally thick.

12 Oct 2013

Study: Depression in Parkinson's patients may reflect impaired striatal dopamine function

According to the Parkinson's Disease Foundation, up to 60% of individuals with Parkinson's disease (PD) exhibit mild to moderate depression, which is often underdiagnosed.

11 Oct 2013

Two scientists from Gladstone Institutes recognized for their contributions to science, medicine

In an unprecedented move, the California Academy of Sciences today will induct two scientists from the Gladstone Institutes', President R. Sanders "Sandy" Williams, MD, and Investigator Katherine Pollard, PhD, as Academy Fellows, bestowing yet another honor on two of San Francisco's most esteemed scientists.

11 Oct 2013

NUS, A*STAR establish joint center to study role of nutrition and development in health, disease in Asia

The National University of Singapore (NUS) and A*STAR will be jointly establishing the S$148 million Singapore Centre for Nutritional Sciences, Metabolic Diseases, and Human Development (SiNMeD).

11 Oct 2013

Depression in Parkinson's disease people associated with reduced dopamine synthesis capacity

According to the Parkinson's Disease Foundation, up to 60% of individuals with Parkinson's disease exhibit mild to moderate depression, which is often underdiagnosed. It is unclear whether depression results from having a debilitating disease or reflects a parallel abnormal change in the brain caused by PD pathophysiology.

11 Oct 2013

Researchers discover how the body's muscles accidentally fall asleep while awake

Normally muscles contract in order to support the body, but in a rare condition known as cataplexy the body's muscles "fall asleep" and become involuntarily paralyzed. Cataplexy is incapacitating because it leaves the affected individual awake, but either fully or partially paralyzed. It is one of the bizarre symptoms of the sleep disorder called narcolepsy.

11 Oct 2013

Running a marathon can damage heart muscle for unfit runners

Investigators who studied a group of recreational marathon runners have established that strenuous exercise such as running a marathon can damage the heart muscle. Although they found the effect is temporary and reversible, they warn that these effects are more widespread in less fit distance runners and that recreational distance runners should prepare properly before marathons.

10 Oct 2013

Muscle News and Research

Mindfulness-based intervention leads to drop in blood pressure

Phase 3 ODYSSEY MONO trial with alirocumab meets primary efficacy endpoint

Senate leaders close in on deal that leaves health law intact

UC researchers receive $2.1M grant from NIH to study molecular mechanisms of muscle fatigue

First Edition: October 15, 2013

Acacia Pharma reports positive results from APD515 Phase II study for treatment of xerostomia

Researchers to present latest findings in emergency medicine research at ACEP13-Scientific Assembly

American Heart Association recommends docs to evaluate patients’ physical activity habits

Statins may increase risk of cataracts among individuals above 30 years old

CNIO researchers perform first exome sequencing for non-infiltrating bladder cancer

Scientists discover genetic mutation associated with low-risk bladder cancer

New approach could help identify specific gene mutations linked to increased disease risk

Men who didn't exercise more likely to have dysfunctional HDL

Deficiency of antioxidant response protein prevents hypertrophic cardiomyopathy

Study: Depression in Parkinson's patients may reflect impaired striatal dopamine function

Two scientists from Gladstone Institutes recognized for their contributions to science, medicine

NUS, A*STAR establish joint center to study role of nutrition and development in health, disease in Asia

Depression in Parkinson's disease people associated with reduced dopamine synthesis capacity

Researchers discover how the body's muscles accidentally fall asleep while awake

Running a marathon can damage heart muscle for unfit runners

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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