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Study shows the true prevalence of statin intolerance worldwide is between 6 to 10%

As many as one in two patients stop taking statins, reduce the dose or take them irregularly because they believe the cholesterol-lowering drugs cause muscle pain and other side-effects.

16 Feb 2022

Inside the tactical tug of war over the controversial Alzheimer’s drug

The drug industry, patient advocates, and congressional Republicans have all attacked federal officials' decision to decline routine Medicare coverage for a controversial Alzheimer's drug.

16 Feb 2022

Study suggests folic acid supplementation linked to increased risk for COVID-19 diagnosis

In a recent study posted to the medRxiv* preprint server, researchers evaluated if folic acid or methotrexate use impacts the risk of coronavirus disease 2019 (COVID-19) diagnosis or associated mortality in the United Kingdom (UK).

15 Feb 2022

Use of immunosuppressants for inflammatory rheumatic diseases and the associated risk of severe COVID-19

A recent study posted to the medRxiv* preprint server investigated the risk of severe/fatal coronavirus disease 2019 (COVID-19) in patients treated with immunosuppressants for inflammatory rheumatic diseases (IRD).

15 Feb 2022

Biomarker could predict pathologic response to chemotherapy among bladder cancer patients

Long-term survival data from the first prospective, randomized biomarker validation trial in patients with muscle-invasive bladder cancer being treated with cisplatin-based chemotherapy before surgery will be reported at the 2022 Genitourinary Cancers Symposium of the American Society of Clinical Oncology (GU ASCO) on February 18, 2022.

15 Feb 2022

The in vitro selection of a remdesivir-resistant SARS-CoV-2 mutation

Researchers select and study an RDV-resistant virus by serial passaging of wild type SARS-CoV-2 in the presence of increasing concentrations of RDV.

15 Feb 2022

Researchers create a comprehensive atlas of cerebrovascular cell types

While neurons and glial cells are by far the most numerous cells in the brain, many other types of cells play important roles. Among those are cerebrovascular cells, which form the blood vessels that deliver oxygen and other nutrients to the brain.

15 Feb 2022

Older woman's estrogen levels may be linked to risk of COVID-19 death

An older woman's estrogen levels may be linked to her chances of dying from COVID-19, with higher levels of the hormone seemingly protective against severe infection, suggests research published in the open access journal BMJ Open.

15 Feb 2022

Antiviral activity assessment of remdesivir against 10 current and former SARS-CoV-2 variant clinical isolates

A new study published demonstrated the in vitro potencies of RDV and GS-441524 through PRA, and nucleoprotein ELISA against SARS-CoV-2 and other VOC/VOIs isolates with specific substitutions in Nsp12.

15 Feb 2022

Medical boards pressured to let it slide when doctors spread covid misinformation

Tennessee's Board of Medical Examiners unanimously adopted in September a statement that said doctors spreading covid misinformation — such as suggesting that vaccines contain microchips — could jeopardize their license to practice.

15 Feb 2022

Researchers overcome key challenge in creating sulfur-based medicines

A key technical challenge in creating new sulfur-based medicines has been overcome by scientists at Nanyang Technological University, Singapore (NTU Singapore), leading to the prospect of many new therapeutic 'weapons' in the fight against disease and illness.

15 Feb 2022

Cardiovascular markers for predicting clinical outcomes in SARS-CoV-2 infection

In a recent study posted to the medRxiv* preprint server, an interdisciplinary team of researchers from Toronto, Canada, characterized the markers of endothelial function and developed micro ribonucleic acid (miRNA) expression atlas in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive and -negative patients admitted to the intensive care unit (ICU).

15 Feb 2022

Regulating inflammation in Alzheimer's disease using a nanocleaner

In this new article publication from Acta Pharmaceutica Sinica B, authors Ting Lei, Zhihang Yang, Xue Xia, Yuxiu Chen, Xiaotong Yang, Rou Xie, Fan Tong, Xiaolin Wang, Huile Gao from Sichuan University, Chengdu, China and Macau University of Science and Technology, Macau, China discuss how nanocleaners can specifically penetrate the blood‒brain barrier at lesions to clean toxic proteins and regulate inflammation in Alzheimer's disease.

14 Feb 2022

Research project receives additional funding to tackle a drug-resistant superbug

A global drive - led by University of the West of Scotland (UWS) - to tackle a drug-resistant superbug has received additional funding.

14 Feb 2022

Antiviral potential of N-acylethanolamine acid amide hydrolase against SARS-CoV-2 and Zika virus

A recent study posted to the bioRxiv* pre-print server investigated the antiviral potential of N-acylethanolamine acid amidase (NAAA) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the Zika virus (ZIKV).

14 Feb 2022

Group cell movement could be harnessed to stop cancer spread, study suggests

Cells push and pull on surrounding tissue to move in groups as they form organs in an embryo, track down invading bacteria, and become cancerous and spread.

14 Feb 2022

RNA capping mechanism of SARS-CoV-2 unveiled

In a recent study posted to the bioRxiv* preprint server, researchers elucidated the mechanism of ribonucleic acid (RNA) capping in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).

14 Feb 2022

UCI biologists discover how a protective mutation may reduce Alzheimer's risk

While the word "mutation" may conjure up alarming notions, a mutation in brain immune cells serves a positive role in protecting people against Alzheimer's disease.

14 Feb 2022

Antihistamines may offer hope for long COVID patients

Researchers offer hope that an inexpensive over-the-counter medication could improve long COVID symptoms for a large proportion of these patients.

14 Feb 2022

Research lays the foundation for developing obesity drugs based on enhancing β-AR signaling

Following up on a 2018 study that identified an epigenetic modifier known as histone deacetylase 11 (HDAC11) as a potential therapeutic target for treating obesity and diabetes, researchers from the University of Colorado School of Medicine have published new research that finds HDAC11 regulates G protein-coupled receptors (GPCRs) called beta-adrenergic receptors (β-ARs).

14 Feb 2022

Drugs News and Research

Study shows the true prevalence of statin intolerance worldwide is between 6 to 10%

Inside the tactical tug of war over the controversial Alzheimer’s drug

Study suggests folic acid supplementation linked to increased risk for COVID-19 diagnosis

Use of immunosuppressants for inflammatory rheumatic diseases and the associated risk of severe COVID-19

Biomarker could predict pathologic response to chemotherapy among bladder cancer patients

The in vitro selection of a remdesivir-resistant SARS-CoV-2 mutation

Researchers create a comprehensive atlas of cerebrovascular cell types

Older woman's estrogen levels may be linked to risk of COVID-19 death

Antiviral activity assessment of remdesivir against 10 current and former SARS-CoV-2 variant clinical isolates

Medical boards pressured to let it slide when doctors spread covid misinformation

Researchers overcome key challenge in creating sulfur-based medicines

Cardiovascular markers for predicting clinical outcomes in SARS-CoV-2 infection

Regulating inflammation in Alzheimer's disease using a nanocleaner

Research project receives additional funding to tackle a drug-resistant superbug

Antiviral potential of N-acylethanolamine acid amide hydrolase against SARS-CoV-2 and Zika virus

Group cell movement could be harnessed to stop cancer spread, study suggests

RNA capping mechanism of SARS-CoV-2 unveiled

UCI biologists discover how a protective mutation may reduce Alzheimer's risk

Antihistamines may offer hope for long COVID patients

Research lays the foundation for developing obesity drugs based on enhancing β-AR signaling

Industry Focus eBook - Cell biology (5th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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