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$50 million PCORI funding approved for studies focused on treating suicidal depression and bipolar depression

Research teams at Mass General Brigham's founding members, Brigham and Women's Hospital and Massachusetts General Hospital, have been approved for more than $50 million in funding awards by the Patient-Centered Outcomes Research Institute for studies focused on treating two important mental health conditions.

26 Jul 2022

Study confirms efficacy of molnupiravir against COVID in a real-life cohort

Researchers report the efficacy and safety of molnupiravir in treating COVID-19.

26 Jul 2022

$31 million PCORI funding for AAFP and Penn State to study the effectiveness of asthma treatments

The American Academy of Family Physicians, in partnership with Penn State College of Medicine, has been approved for a $31 million funding award by the Patient-Centered Outcomes Research Institute to study the comparative effectiveness of asthma treatments.

26 Jul 2022

Poll: Many older adults use integrative medicine strategy to ease physical or mental health symptoms

Nearly 40% of older adults currently use at least one integrative medicine strategy to try to ease symptoms of a physical or mental health issue, or to help them relax, a new poll finds.

26 Jul 2022

Medication optimization needed in the primary care setting for managing COPD patients

Researchers conducted a study to describe the demographic and clinical characteristics of patients receiving care for chronic obstructive pulmonary disease in the U.S. primary care setting.

26 Jul 2022

Insights into molecular folding of AAT protein will help develop new therapies for alpha-1 antitrypsin deficiency

In a major new development in the quest to develop better gene therapies with which to treat a host of diseases, researchers at the University of Massachusetts Amherst and UMass Chan Medical School recently announced that they have mapped the expression and maturation of the protein alpha-1 antitrypsin (AAT) with unprecedented clarity.

25 Jul 2022

Researchers investigate a drug used for neuromuscular weakness as potential treatment for botulism

Wake Forest Institute for Regenerative Medicine (WFIRM) researchers are investigating a drug used to treat neuromuscular weakness as a potential treatment for botulism, a rare but serious disease.

25 Jul 2022

What is the role of psychedelic drugs in the treatment of psychiatric disorders?

A new study aimed to determine the clinical applications of psychedelic drugs along with psychedelic-assisted therapy for different psychiatric disorders.

25 Jul 2022

Using CRISPR technology to successfully prevent and treat SARS-CoV-2 infections

In what is believed to be a first, a research team led by Duke Health has demonstrated a way to use CRISPR technology to successfully prevent and treat COVID infections.

25 Jul 2022

Renowned neurologist to join the staff leadership team of The American Heart Association

The American Heart Association, the world's leading nonprofit organization focused on heart and brain health for all, has announced that Mitchell S.V. Elkind, M.D., M.S., FAHA, longtime volunteer of the Association and renowned neurologist, will be joining the staff leadership team this fall as Chief Clinical Science Officer.

25 Jul 2022

Study identifies risks in the use of CRISPR therapeutics

The researchers caution: "The CRISPR genome editing method is very effective, but not always safe. Sometimes cleaved chromosomes do not recover and genomic stability is compromised - which in the long run might promote cancer."

25 Jul 2022

Two UTHSC research teams receive CORNET Awards for novel projects

Two research teams at the University of Tennessee Health Science Center (UTHSC) have been awarded the 2022 UTHSC Collaborative Research Network (CORNET)-Functional Genomics Award. Each team will receive $50,000 to support their novel projects.

22 Jul 2022

Maternal antibodies may play a key role in protecting infants from congenital HCMV infections

Antibodies that summon virus-engulfing white blood cells may play an important role in protecting infants from potentially serious congenital infection with human cytomegalovirus (HCMV), according to a study led by an investigator at Weill Cornell Medicine and NewYork-Presbyterian.

22 Jul 2022

Improving the immune defenses against blood cancer

For patients with lymphoma, multiple myeloma, or certain types of leukemia, treatment with chimeric antigen receptor T cells (CAR T cells) is sometimes the last chance of overcoming the cancer.

22 Jul 2022

New treatment guidelines published for anorectal abscess, anal fistula, and rectovaginal fistula

The American Society of Colon and Rectal Surgeons has issued updated guidelines for physicians, published in Diseases of the Colon & Rectum, about how to treat problems of the anus and rectum called anorectal abscess, anal fistula, and rectovaginal fistula.

22 Jul 2022

New biomimetic formulation developed to tackle glioblastoma multiforme

Glioblastoma multiforme (GBM) is an aggressive brain cancer with a poor prognosis and few treatment options. New and effective approaches for GBM treatment are therefore urgently needed.

22 Jul 2022

A major breakthrough toward new treatments for Type 1 and Type 2 diabetes

A world-first study by Monash University, in Melbourne, Australia has discovered a pathway to the regeneration of insulin in pancreatic stem cells, a major breakthrough toward new therapies to treat Type 1 and Type 2 diabetes.

22 Jul 2022

Alzheimer's disease and anti-amyloid therapeutic approaches

An estimated 50 million people around the world have Alzheimer's disease (AD), and perhaps twice that number are unknowingly "incubating" the disease during its long presymptomatic period.

21 Jul 2022

Immuno-infrared sensor identifies Alzheimer's disease in the blood up to 17 years in advance

A sensor identifies misfolded protein biomarkers in the blood. This offers a chance to detect Alzheimer's disease before any symptoms occur. Researchers intend to bring it to market maturity.

21 Jul 2022

Women a history of endometriosis may have greater stroke risk

A large, prospective study found that women with endometriosis may have a higher risk of stroke compared to women without the chronic inflammatory condition, according to new research published today in Stroke, the peer-reviewed flagship journal of the American Stroke Association, a division of the American Heart Association.

21 Jul 2022

Therapy News and Research

$50 million PCORI funding approved for studies focused on treating suicidal depression and bipolar depression

Study confirms efficacy of molnupiravir against COVID in a real-life cohort

$31 million PCORI funding for AAFP and Penn State to study the effectiveness of asthma treatments

Poll: Many older adults use integrative medicine strategy to ease physical or mental health symptoms

Medication optimization needed in the primary care setting for managing COPD patients

Insights into molecular folding of AAT protein will help develop new therapies for alpha-1 antitrypsin deficiency

Researchers investigate a drug used for neuromuscular weakness as potential treatment for botulism

What is the role of psychedelic drugs in the treatment of psychiatric disorders?

Using CRISPR technology to successfully prevent and treat SARS-CoV-2 infections

Renowned neurologist to join the staff leadership team of The American Heart Association

Study identifies risks in the use of CRISPR therapeutics

Two UTHSC research teams receive CORNET Awards for novel projects

Maternal antibodies may play a key role in protecting infants from congenital HCMV infections

Improving the immune defenses against blood cancer

New treatment guidelines published for anorectal abscess, anal fistula, and rectovaginal fistula

New biomimetic formulation developed to tackle glioblastoma multiforme

A major breakthrough toward new treatments for Type 1 and Type 2 diabetes

Alzheimer's disease and anti-amyloid therapeutic approaches

Immuno-infrared sensor identifies Alzheimer's disease in the blood up to 17 years in advance

Women a history of endometriosis may have greater stroke risk

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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