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Identifying gene defects may help develop individualised treatments for prostate cancer patients

The current method of treating prostate cancer involves identifying gene defects, which could help with the diagnosis of cancer and the development of individualised cancer treatments for patients.

7 Nov 2016

New study examines genetic factors underlying poor tolerance to shift work

Some people adapt easily to shift work, but not everyone can handle constant disruptions to their daily rhythm. Finnish researchers have now found that a melatonin receptor gene influences tolerance to shift work.

5 Nov 2016

WSU researcher finds a way to reduce development of cancer cells

A Washington State University researcher has developed a way to reduce the development of cancer cells that are an infrequent but dangerous byproduct of gene therapy.

5 Nov 2016

Smoking causes added mutations in DNA of lung cells

A paper published today in Science shows that smoking tobacco causes added mutations in the DNA of lung cells and in the DNA of other cells in the body. This is the first study to show the process by which smoking causes these cancers.

4 Nov 2016

Rutgers Cancer Institute researcher receives grant to explore cell pathway in triple-negative breast cancer

Rutgers Cancer Institute of New Jersey researcher Michael L. Gatza, PhD, has received a $200,000 V Scholar Grant from The V Foundation for Cancer Research to explore a cell pathway in triple-negative breast cancer.

4 Nov 2016

Ebola mutation increased infectivity

New research finds a genetic mutation in the Ebola virus that enabled it to target human cells more effectively during the recent Ebola epidemic.

4 Nov 2016

Genetic variation, environmental conditions can have significant impact on human health

Scientists at the Wayne State University School of Medicine's Center for Molecular Medicine and Genetics have shown for the first time the extent by which interactions between environmental exposures and genetic variation across individuals have a significant impact on human traits and diseases like diabetes, heart disease and obesity, strengthening the case for precision medicine initiatives.

4 Nov 2016

Problems with nuclear membrane play role in leukemia, heart disease and aging disorders

We put things into a container to keep them organized and safe. In cells, the nucleus has a similar role: keeping DNA protected and intact within an enveloping membrane.

2 Nov 2016

Researchers find certain short junk DNA play key role in development of Ewing sarcoma

The stretches of DNA between genes, littered with repeating sequences, were once considered the "junk of the genome," but scientists are learning that some of this junk is far from harmless clutter.

2 Nov 2016

Research shows way to directly target genes within specific cell type

The cornerstone of genetics is the loss-of-function experiment. In short, this means that to figure out what exactly gene X is doing in a tissue of interest—be it developing brain cells or a pancreatic tumor—you somehow cut out, switch off or otherwise destroy gene X in that tissue and then watch what happens.

1 Nov 2016

Illumina donates more than 95,000 human genetic variants to ClinVar database

Illumina, Inc. announced that it has contributed over 95,000 human genetic variants to ClinVar, a public database hosted by the National Center for Biotechnology Information (NCBI).

From Illumina, Inc. 1 Nov 2016

Scientists identify essential enzymes for efficient and precise repair of damaged DNA

Scientists at The Australian National University and Heidelberg University in Germany have found an essential component in the DNA repair process which could open the door to the development of new cancer drugs.

31 Oct 2016

Research shows genetic link between mitochondrial DNA and autism

Cornell University researchers have confirmed a genetic link between mitochondrial DNA (mtDNA), which is passed on from the mother, and some forms of autism spectrum disorder (ASD).

31 Oct 2016

New study clears “Patient Zero” of responsibility for HIV in US

A new genetic analysis has shown that the French-Canadian flight attendant Gaétan Dugas who was posthumously blamed for spreading HIV across North America, was not the “Patient Zero” of the epidemic. Dugas became notorious as the person responsible for the US AIDS crisis after he slept with men in California and New York during the early 1980s.

28 Oct 2016

Researchers developing guidelines on ethics and best practices for biorepositories

What if a patient gave permission to a researcher at her local hospital to use her blood or specimen for research, and later the researcher decided to share that sample with others?

27 Oct 2016

NIH researchers identify novel role for Hsp60 protein in tissue regeneration and wound healing

National Institutes of Health researchers have identified a novel role for a gene known as heat shock protein 60 (Hsp60), finding that it is critical in tissue regeneration and wound healing.

27 Oct 2016

Supercomputer simulations of p53 protein could boost future anti-cancer drug discovery

Even though it's almost impossible to see, computational biophysicist Rommie Amaro is using the Stampede supercomputer at the Texas Advanced Computing Center at The University of Texas at Austin to model the largest atomic level system of the tumor suppression protein p53 to date -- over 1.5 million atoms.

27 Oct 2016

Genome News and Research

Identifying gene defects may help develop individualised treatments for prostate cancer patients

New study examines genetic factors underlying poor tolerance to shift work

WSU researcher finds a way to reduce development of cancer cells

Smoking causes added mutations in DNA of lung cells

Rutgers Cancer Institute researcher receives grant to explore cell pathway in triple-negative breast cancer

Ebola mutation increased infectivity

Genetic variation, environmental conditions can have significant impact on human health

Problems with nuclear membrane play role in leukemia, heart disease and aging disorders

Researchers find certain short junk DNA play key role in development of Ewing sarcoma

Research shows way to directly target genes within specific cell type

Illumina donates more than 95,000 human genetic variants to ClinVar database

Scientists identify essential enzymes for efficient and precise repair of damaged DNA

Research shows genetic link between mitochondrial DNA and autism

New study clears “Patient Zero” of responsibility for HIV in US

Researchers developing guidelines on ethics and best practices for biorepositories

NIH researchers identify novel role for Hsp60 protein in tissue regeneration and wound healing

Supercomputer simulations of p53 protein could boost future anti-cancer drug discovery

Scientists identify commonly affected genes sets among people with three mental disorders

Gene therapy may be effective method for treating Niemann-Pick disease, type C1

Yale researchers use new gene editing technique to correct mutations that cause thalassemia

The art of CRISPR: The power and promise of gene editing eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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