Hormone News and Research

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A hormone is a chemical released by one or more cells that affects cells in other parts of the organism. Only a small amount of hormone is required to alter cell metabolism. It is essentially a chemical messenger that transports a signal from one cell to another.

DARA's KRN5500 meets primary end-points in Phase II study for chemotherapy-induced neuropathic pain

Thanks to greater awareness, earlier detection and improving therapeutic agents, people with cancer are living longer than ever before. One of the consequences of living longer is the symptom burden of cancer survivorship, which may have a substantial impact on quality of life for many survivors. One such burden is the pain syndromes resulting from cancer treatments.

17 Sep 2011

New diabetes drugs linked to increased risk of pancreatitis and pancreatic cancer

Two newer drugs used to treat Type 2 diabetes could be linked to a significantly increased risk of developing pancreatitis and pancreatic cancer, and one could also be linked to an increased risk of thyroid cancer, according to a new UCLA study.

17 Sep 2011

Linagliptin demonstrates durable reductions in blood glucose for T2D adults

Boehringer Ingelheim and Eli Lilly and Company today announced results of a 102 week Phase III study for linagliptin, which show meaningful and durable reductions in blood glucose for adults with type 2 diabetes.

16 Sep 2011

Estrogen therapy can reverse progression of pulmonary hypertension

UCLA researchers have found that the hormone estrogen may help reverse advanced pulmonary hypertension, a rare and serious condition that affects 2 to 3 million individuals in the U.S., mostly women, and can lead to heart failure.

16 Sep 2011

KAI enters KAI-4169 development and commercialization agreement with Ono

KAI Pharmaceuticals, Inc., a privately held drug discovery and development company, today announced the signing of an agreement with Ono Pharmaceutical Co., Ltd. for the development and commercialization in Japan of KAI-4169, KAI's lead product candidate.

15 Sep 2011

Positive results from PROLOR Biotech's Factor VIIa-CTP preclinical study on hemophilia

PROLOR Biotech, Inc.,, today reported positive results from a comparative study of its biobetter longer-acting version of the hemophilia drug Factor VIIa (Factor VIIa-CTP) in hemophilic mice.

15 Sep 2011

BGU study: Voting causes stress and induces measurable hormonal changes

As the United States nears another election day, researchers at Ben-Gurion University of the Negev (BGU) have determined scientifically, for the first time, that voting is a stressful event, inducing measurable hormonal changes.

15 Sep 2011

Heart specialists reveal how pacemaker works at the biological level

Heart specialists at Johns Hopkins have figured out how a widely used pacemaker for heart failure, which makes both sides of the heart beat together to pump effectively, works at the biological level.

15 Sep 2011

Novo Nordisk's insulin degludec reduces blood sugar in patients with type 2 diabetes

Ultra-long-acting insulin degludec, an investigational basal insulin being developed by Novo Nordisk, showed significant blood sugar reductions in patients with type 2 diabetes.

From Novo Nordisk 15 Sep 2011

OXTR gene associated with optimism, self-esteem and mastery

UCLA life scientists have identified for the first time a particlular gene's link to optimism, self-esteem and "mastery," the belief that one has control over one's own life - three critical psychological resources for coping well with stress and depression.

15 Sep 2011

Novo Nordisk announces free diabetes educational e-book series

Today, Novo Nordisk, a world leader in diabetes care, launched a free 5-volume diabetes educational e-book series, designed to help patients work with their health care team to better manage their diabetes. The e-book series is part of Cornerstones4Care™, an innovative patient support program that provides highly customizable diabetes information through the comprehensive interactive website www.Cornerstones4Care.com.

From Novo Nordisk 14 Sep 2011

Positive data from Aeterna Zentaris' AEZS-108 Phase 2 study on advanced endometrial cancer

Aeterna Zentaris Inc. earlier today, presented positive final Phase 2 efficacy and safety data for its targeted cytotoxic luteinizing hormone releasing hormone (LHRH) analog, AEZS-108, in advanced endometrial cancer.

14 Sep 2011

Natural S-equol supplement does not increase risk of estrogen-sensitive breast cancer

Consuming the soy germ-based compound Natural S-equol and the supplement SE5-OH containing Natural S-equol did not increase the risk of estrogen-sensitive breast cancer, according to a study in the September issue of the peer-reviewed journal Food and Chemical Toxicology.

14 Sep 2011

IUDs may protect from cervical cancer

According to the results of an international study, coil contraceptive devices might protect women against developing cervical cancer even though they don't stop the infection that commonly leads to the disease.

14 Sep 2011

Thyroid-stimulating hormone can promote bone growth

Researchers at Mount Sinai School of Medicine have found that thyroid-stimulating hormone (TSH), a hormone produced in the anterior pituitary gland that regulates endocrine function in the thyroid gland, can promote bone growth independent of its usual thyroid functions.

14 Sep 2011

Lignans lower risk of death in women with breast cancer

Phytoestrogens are plant compounds which, in the human body, can attach to the receptors for the female sexual hormone estrogen and which are taken in with our daily diet. A number of findings have attributed a cancer protective effect to these plant hormones. At DKFZ, a team headed by Prof. Dr. Jenny Chang-Claude summarized the results of several studies in a meta-analysis last year and showed that a diet rich in phytoestrogens lowers the risk of developing breast cancer after menopause.

14 Sep 2011

Fathers and family men low on testosterone: Study

A new study shows that men who spend time with their children have lower levels of testosterone than single guys. The study shows that family men experience a biological shift that may awaken their nurturing side.

13 Sep 2011

A squirt of insulin up the nose for prevention of Alzheimer’s disease

Researchers have noted in a small pilot study that squirting insulin deep into the nose where it travels to the brain might hold early Alzheimer’s disease at bay. At present there are no effective ways to prevent or delay the progress of Alzheimer’s. More than 5.4 million Americans and 35 million people worldwide have Alzheimer's, the most common form of dementia.

13 Sep 2011

Lantus initiation may help limit weight gain in type 2 diabetes patients

Sanofi announced today data that demonstrates that initiating Lantus® (insulin glargine [rDNA origin] injection) in type 2 diabetes patients leads to better glycemic control and comparable and modest weight gain versus a comparator group consisting of other insulins, oral antidiabetics and dietary changes.

12 Sep 2011

Oncothyreon commences enrollment in PX-866 Phase 2 trial for metastatic castration-resistant prostate cancer

Oncothyreon Inc. today announced enrollment of the first patient in a Phase 2 trial of PX-866 in patients with recurrent or metastatic castration-resistant prostate cancer. PX-866 is a small molecule compound designed to inhibit the activity of phosphatidylinositol-3-kinase (PI-3K), a component of an important cell survival signaling pathway.

12 Sep 2011

Hormone News and Research

Further Reading

DARA's KRN5500 meets primary end-points in Phase II study for chemotherapy-induced neuropathic pain

New diabetes drugs linked to increased risk of pancreatitis and pancreatic cancer

Linagliptin demonstrates durable reductions in blood glucose for T2D adults

Estrogen therapy can reverse progression of pulmonary hypertension

KAI enters KAI-4169 development and commercialization agreement with Ono

Positive results from PROLOR Biotech's Factor VIIa-CTP preclinical study on hemophilia

BGU study: Voting causes stress and induces measurable hormonal changes

Heart specialists reveal how pacemaker works at the biological level

Novo Nordisk's insulin degludec reduces blood sugar in patients with type 2 diabetes

OXTR gene associated with optimism, self-esteem and mastery

Novo Nordisk announces free diabetes educational e-book series

Positive data from Aeterna Zentaris' AEZS-108 Phase 2 study on advanced endometrial cancer

Natural S-equol supplement does not increase risk of estrogen-sensitive breast cancer

IUDs may protect from cervical cancer

Thyroid-stimulating hormone can promote bone growth

Lignans lower risk of death in women with breast cancer

Fathers and family men low on testosterone: Study

A squirt of insulin up the nose for prevention of Alzheimer’s disease

Lantus initiation may help limit weight gain in type 2 diabetes patients

Oncothyreon commences enrollment in PX-866 Phase 2 trial for metastatic castration-resistant prostate cancer

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