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Loyola among first health systems to offer absorbable stent to heart patients

Loyola Medicine will be among the first health systems in the country to offer heart patients a new stent that is absorbed by the body once it has served its purpose.

7 Jul 2016

New ESMO guidelines reflect personalized approach for management of metastatic colorectal cancer

ESMO, the leading European professional organisation for medical oncology, has released new consensus guidelines for the management of metastatic colorectal cancer that reflect an increasingly personalized approach to treatment, as published online today in Annals of Oncology.

7 Jul 2016

Minoryx Therapeutics initiates phase 1 clinical trial of MIN-102

Minoryx Therapeutics, a drug development company specialized in the discovery and development of new drugs for orphan diseases, today announces the initiation of its first-in-man Phase 1 clinical trial for its lead compound MIN-102.

7 Jul 2016

Early attention problems in children can have lasting impact on academic outcomes

Children with attention problems in early childhood were 40 percent less likely to graduate from high school, says a new study from Duke University that examines how early childhood characteristics affect academic performance.

7 Jul 2016

Liraglutide drug lowers blood sugar levels in diabetic patients taking large doses of insulin

When Amy Sweat was 19 years old, while she was in the hospital recovering from surgery, she was diagnosed with Type 2 diabetes. Ms. Sweat was treated for her diabetes, first on oral drugs, then on increasingly larger doses of insulin, but the years went by and she never was able to achieve good blood sugar control.

6 Jul 2016

Diabetes drug metformin could help reduce toxic acid levels linked to MSUD

Maple Syrup Urine Disease (MSUD) is a rare inherited metabolic disorder involving the dysfunction of an enzyme which breaks down three essential amino acids: leucine, isoleucine and valine.

6 Jul 2016

Tiny micro-vesicle structures may help predict probability of developing Alzheimer's dementia

Researchers at University of California San Diego School of Medicine say tiny micro-vesicle structures used by neurons and other cells to transport materials internally or dispose of them externally carry tell-tale proteins that may help to predict the likelihood of mild cognitive impairment (MCI) developing into full-blown Alzheimer's disease (AD).

6 Jul 2016

European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

Amgen has announced that the European Commission (EC) has approved a variation to the marketing authorization for Kyprolis® (carfilzomib) to include use in combination with dexamethasone alone for adult patients with multiple myeloma who have received at least one prior therapy. The extended indication marks the second approval for Kyprolis by the EC in less than a year.

6 Jul 2016

Quantum Genomics initiates Phase IIa trial for heart failure

Quantum Genomics, a biopharmaceutical company with the mission of developing new therapies for unmet medical needs in the field of cardiovascular diseases, today announced the initiation of its Phase IIa multicentric clinical trial of GQC101, entitled QUID HF (QUantum Genomics Incremental Dosing in Heart Failure), for the treatment of patients with chronic heart failure. The first three clinical centres of the European trial have been opened in France and Norway.

6 Jul 2016

Deutetrabenazine may help improve chorea symptoms in patients with HD

People with Huntington disease (HD) experienced improvements in chorea while taking deutetrabenazine (SD-809) compared to placebo, according to a paper published today in the Journal of the American Medical Association.

6 Jul 2016

Immunotherapy in conjunction with drugs could be effective in treating pancreatic cancer

While immune therapy has proven effective in treating certain types of cancer, especially lung cancer and melanoma, tumors of the pancreas remain among the most difficult to treat and, so far, are impervious to immune-based therapies.

4 Jul 2016

Tablet-based system allows physicians to diagnose stroke patients in pre-hospital setting

A clinical trial testing mobile videoconferencing as a means for physicians to diagnose stroke patients while they're being transported to the hospital has found that a tablet-based system produced diagnoses highly correlating with a bedside assessment -- a finding that could have important implications for the early treatment of stroke and for preventing the disability it causes.

1 Jul 2016

Everolimus combined with standard R-CHOP therapy shows promise in treating DLBCL patients

The targeted therapy everolimus may be safely combined with R-CHOP for new, untreated diffuse large B-cell lymphoma according to the results of a pilot study by Mayo Clinic researchers published in the Lancet Haematology.

30 Jun 2016

Transorbital ACS can improve vision in patients with glaucoma, optic nerve damage

Vision loss due to glaucoma or optic nerve damage is generally considered irreversible. Now a new prospective, randomized, multi-center clinical trial demonstrates significant vision improvement in partially blind patients after 10 days of noninvasive, transorbital alternating current stimulation.

30 Jun 2016

Stem cell procedure may be safe for ALS patients

A phase II clinical trial in people with amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, suggests that transplanting human stem cells into the spinal cord may be done safely.

30 Jun 2016

FDA approves Raindrop Near Vision Inlay device for patients with presbyopia

The U.S. Food and Drug Administration today approved the Raindrop Near Vision Inlay, a device implanted in the cornea (the clear, front surface) of one eye to improve near vision in certain patients with presbyopia.

30 Jun 2016

Simple 7-item screening device can help detect patients at risk for COPD

A simple 7-item screening tool can help clinicians identify patients at risk for chronic obstructive pulmonary disease (COPD), even if they are not experiencing any symptoms.

29 Jun 2016

Tiny doses of anti-HIV drug may be effective for treating Alzheimer's disease

For a promising pathway to treating Alzheimer's patients, "aim here." That's what National Institute of Standards of Technology researchers advised collaborators hunting for molecules that, by linking to a normally occurring enzyme, rev up the brain's capacity for clearing cholesterol--a boost associated with improvements in memory and other benefits in animal studies.

29 Jun 2016

Epclusa drug receives FDA approval for treating adult patients with chronic HCV

The U.S. Food and Drug Administration approved Epclusa to treat adult patients with chronic hepatitis C virus (HCV) both with and without cirrhosis (advanced liver disease).

28 Jun 2016

'Novel' analysis addresses antiplatelet benefits in real-world CHD patients

Researchers demonstrate a means of gauging the effects of drugs tested in randomised trials in real-world patients.

28 Jun 2016

Clinical Trial News and Research

Loyola among first health systems to offer absorbable stent to heart patients

New ESMO guidelines reflect personalized approach for management of metastatic colorectal cancer

Minoryx Therapeutics initiates phase 1 clinical trial of MIN-102

Early attention problems in children can have lasting impact on academic outcomes

Liraglutide drug lowers blood sugar levels in diabetic patients taking large doses of insulin

Diabetes drug metformin could help reduce toxic acid levels linked to MSUD

Tiny micro-vesicle structures may help predict probability of developing Alzheimer's dementia

European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

Quantum Genomics initiates Phase IIa trial for heart failure

Deutetrabenazine may help improve chorea symptoms in patients with HD

Immunotherapy in conjunction with drugs could be effective in treating pancreatic cancer

Tablet-based system allows physicians to diagnose stroke patients in pre-hospital setting

Everolimus combined with standard R-CHOP therapy shows promise in treating DLBCL patients

Transorbital ACS can improve vision in patients with glaucoma, optic nerve damage

Stem cell procedure may be safe for ALS patients

FDA approves Raindrop Near Vision Inlay device for patients with presbyopia

Simple 7-item screening device can help detect patients at risk for COPD

Tiny doses of anti-HIV drug may be effective for treating Alzheimer's disease

Epclusa drug receives FDA approval for treating adult patients with chronic HCV

'Novel' analysis addresses antiplatelet benefits in real-world CHD patients

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