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First synthetic membranes made without solvents on silicon surfaces

Artificial membranes mimicking those found in living organisms have many potential applications ranging from detecting bacterial contaminants in food to toxic pollution in the environment to dangerous diseases in people.

10 Sep 2014

Researchers pave way for development of new generation of chemotherapy drugs

A new mechanism to inhibit proteasomes, protein complexes that are a target for cancer therapy, is the topic of an article published in the journal Chemistry & Biology.

10 Sep 2014

Researchers aim to safely and quickly suppress food allergies in human

In mice, the answer appears to be "yes," but making sure the same can happen in humans is a task that Fred Finkelman, MD, professor of medicine and pediatrics in the University of Cincinnati's (UC) College of Medicine and a researcher at Cincinnati Children's Hospital Medical Center, is attempting to tackle.

9 Sep 2014

NanoTracker™ Optical Tweezers system used at Leiden University to study the organisation of genomic DNA

JPK Instruments, a world-leading manufacturer of nanoanalytic instrumentation for research in life sciences and soft matter, reports on the use of the NanoTracker™ Optical Tweezers system in the Laboratory of Molecular Genetics in the Leiden Institute of Chemistry at Leiden University.

9 Sep 2014

New potential therapeutic targets for treatment of pulmonary arterial hypertension

Two new potential therapeutic targets for the treatment of pulmonary arterial hypertension, a deadly disease marked by high blood pressure in the lungs, have been identified by researchers at the University of Illinois at Chicago.

9 Sep 2014

New discovery could help efforts to produce more effective vaccines

The best defense is a good offense, especially when it comes to the immune system. The troops that respond to an infection are split into two squadrons, and, until recently, it seemed that the two were independent, without much interaction.

9 Sep 2014

Protein RBM4 drastically decreases multiple forms of human cancer

Researchers from the UNC School of Medicine have discovered that the protein RBM4, a molecule crucial to the process of gene splicing, is drastically decreased in multiple forms of human cancer, including lung and breast cancers.

9 Sep 2014

Cholera against cholera: an interview with Dr Bruce Turnbull, University of Leeds

Cholera bacteria, and other types of bacteria that cause diarrheal diseases, infect your intestines where they release AB5 protein toxins – that is they have a single toxic A-subunit that is linked to a pentamer of B-subunits that act as the delivery vehicle to transport the A-subunit into the cells.

8 Sep 2014

Novira completes Phase 1a clinical study of NVR-1221 for treatment of HBV infection

Novira Therapeutics, Inc., a privately held biopharmaceutical company developing novel therapies for curative treatment of chronic hepatitis B virus (HBV) infection, today announced successful completion of a Phase 1a clinical study of NVR-1221.

4 Sep 2014

DNA regions that contained telomeres generate RNAs

RNA is one of the most primitive molecules associated with life that has awakened most interest over the last decade; a sister molecule to cellular DNA from which it originates via a process called transcription.

4 Sep 2014

Scientists aim to develop rapid test system for immune dysfunction to treat cystic fibrosis

Cystic fibrosis (CF) is a frequent genetic disease affecting the lung and the gastrointestinal tract. Scientists from the Helmholtz Zentrum München now have shown that many of the adult patients with CF in addition lack a cell surface molecule, which is important for immune defence. The results have been published recently in the 'Journal of Molecular Medicine'.

4 Sep 2014

New way to reduce abnormal blood vessel growth and leakage in eye

Working with mice, a multicenter team of researchers has found a new way to reduce the abnormal blood vessel growth and leakage in the eye that accompany some eye diseases. The finding could lead to the development of new drugs for wet macular degeneration and diabetic macular edema.

4 Sep 2014

Neuroscientist discovers new mechanism that can reverse chronic pain

It's in the brain where we perceive the unpleasant sensations of pain, and researchers have long been examining how calcium channels in the brain and peripheral nervous system contribute to the development of chronic pain conditions.

4 Sep 2014

Artificial cells to devour undesirables: an interview with Dr. Takanari Inoue

If junk is not removed, pathological conditions can develop. For example, in one condition, the neutrophil count significantly decreases. Neutrophils remove pathogens and people with a reduced neutrophil count are more prone to infection, especially to rare bacteria that wouldn’t cause infection under normal conditions.

3 Sep 2014

Using molecular imaging probes diabetic retinopathy can be detected at molecular level

A new study published in the September issue of The FASEB Journal, identifies a novel strategy to diagnose the leading cause of blindness in adults, diabetic retinopathy, before irreversible structural damage has occurred.

3 Sep 2014

New approach to turn diseased cells into unique manufacturing sites for treating muscular dystrophy

In a new study that could ultimately lead to many new medicines, scientists from the Florida campus of The Scripps Research Institute (TSRI) have adapted a chemical approach to turn diseased cells into unique manufacturing sites for molecules that can treat a form of muscular dystrophy.

3 Sep 2014

Finding could lead researchers to better understand development of psychiatric disorders

Some people take stress in stride; others are done in by it. New research at Rockefeller University has identified the molecular mechanisms of this so-called stress gap in mice with very similar genetic backgrounds - a finding that could lead researchers to better understand the development of psychiatric disorders such as anxiety and depression.

2 Sep 2014

Flow through pain-sensing molecule helps worms adapt to pain

When you accidentally touch a hot oven, you rapidly pull your hand away. Although scientists know the basic neural circuits involved in sensing and responding to such painful stimuli, they are still sorting out the molecular players.

2 Sep 2014

Scientists develop synthetic amino acid that can impact 3D structure of bioactive peptides

One of the greatest challenges in modern medicine is developing drugs that are highly effective against a target, but with minimal toxicity and side-effects to the patient. Such properties are directly related to the 3D structure of the drug molecule.

1 Sep 2014

Scientists identify developmental on-off switch for Streptomyces

Scientists have identified the developmental on-off switch for Streptomyces, a group of soil microbes that produce more than two-thirds of the world's naturally derived antibiotic medicines.

30 Aug 2014

Molecule News and Research

First synthetic membranes made without solvents on silicon surfaces

Researchers pave way for development of new generation of chemotherapy drugs

Researchers aim to safely and quickly suppress food allergies in human

NanoTracker™ Optical Tweezers system used at Leiden University to study the organisation of genomic DNA

New potential therapeutic targets for treatment of pulmonary arterial hypertension

New discovery could help efforts to produce more effective vaccines

Protein RBM4 drastically decreases multiple forms of human cancer

Cholera against cholera: an interview with Dr Bruce Turnbull, University of Leeds

Novira completes Phase 1a clinical study of NVR-1221 for treatment of HBV infection

DNA regions that contained telomeres generate RNAs

Scientists aim to develop rapid test system for immune dysfunction to treat cystic fibrosis

New way to reduce abnormal blood vessel growth and leakage in eye

Neuroscientist discovers new mechanism that can reverse chronic pain

Artificial cells to devour undesirables: an interview with Dr. Takanari Inoue

Using molecular imaging probes diabetic retinopathy can be detected at molecular level

New approach to turn diseased cells into unique manufacturing sites for treating muscular dystrophy

Finding could lead researchers to better understand development of psychiatric disorders

Flow through pain-sensing molecule helps worms adapt to pain

Scientists develop synthetic amino acid that can impact 3D structure of bioactive peptides

Scientists identify developmental on-off switch for Streptomyces

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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