Stroke News and Research

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A stroke is a medical emergency. Strokes happen when blood flow to your brain stops. Within minutes, brain cells begin to die. There are two kinds of stroke. The more common kind, called ischemic stroke, is caused by a blood clot that blocks or plugs a blood vessel in the brain. The other kind, called hemorrhagic stroke, is caused by a blood vessel that breaks and bleeds into the brain. "Mini-strokes" or transient ischemic attacks (TIAs), occur when the blood supply to the brain is briefly interrupted.

Cryptogenic stroke frequent and recurrent

Cryptogenic ischaemic strokes and transient ischaemic attacks frequently recur, despite having no identifiable cause, show findings from the Oxford Vascular Study.

4 Aug 2015

IP10 levels linked to HBsAg decline during TDF treatment

Baseline serum interferon-inducible protein 10 levels predict hepatitis B surface antigen reduction in patients with hepatitis B e antigen-negative chronic hepatitis B virus infection treated with tenofovir disoproxil fumarate, findings indicate.

4 Aug 2015

Baseline HBsAg, platelet count predict spontaneous HBsAg seroclearance

Hepatitis B surface antigen level and platelet count at baseline are significantly associated with spontaneous HBsAg seroclearance in hepatitis B virus carriers and those with chronic infection, research suggests.

4 Aug 2015

Genotype A HBV mapped in acute, chronic Japanese patients

Not only is genotype A the most common genotype among Japanese patients with acute hepatitis B virus infection, but its prevalence is spreading among young adults with chronic HBV infection, shows a nationwide study.

4 Aug 2015

Researchers discover how neurons help learn new motor skills

It takes a surprisingly small cluster of brain cells deep within the cerebellum to learn how to serve a tennis ball or line up a hockey shot. Researchers at McGill University led by Kathleen Cullen from the Department of Physiology have discovered that to learn new motor skills, neurons within the cerebellum engage in elegant, virtually mathematical, computations to quickly compare expected and actual sensory feedback. They then quickly readjust, changing the strength of connections between other neurons to form new patterns in the brain in order to accomplish the task at hand.

4 Aug 2015

Study provides mechanism for EDNRB gene's role in adaptation to life at high altitudes

Ethiopians have lived at high altitudes for thousands of years, providing a natural experiment for studying human adaptations to low oxygen, a condition known as hypoxia. One factor that may enable Ethiopians to tolerate high altitudes and hypoxia is the endothelin receptor type B (EDNRB) gene.

4 Aug 2015

MD Anderson scientists reveal role of metabolic enzyme fumarase in DNA repair

DNA double-strand breaks (DSBs) are the worst possible form of genetic malfunction that can cause cancer and resistance to therapy. New information published this week reveals more about why this occurs and how these breaks can be repaired.

4 Aug 2015

Researchers uncover strong evidence for genetic causes of cerebral palsy

Cerebral palsy (CP) is the most common cause of physical disability in children. It has historically been considered to be caused by factors such as birth asphyxia, stroke and infections in the developing brain of babies.

3 Aug 2015

Atomic level images reveal how neuropeptide hormone neurotensin may activate its receptors

Many hormones and neurotransmitters work by binding to receptors on a cell's exterior surface. This activates receptors causing them to twist, turn and spark chemical reactions inside cells.

3 Aug 2015

New non-invasive spinal cord stimulation helps paralyzed men voluntarily move their legs

Five men with complete motor paralysis were able to voluntarily generate step-like movements thanks to a new strategy that non-invasively delivers electrical stimulation to their spinal cords, according to a new study funded in part by the National Institutes of Health. The strategy, called transcutaneous stimulation, delivers electrical current to the spinal cord by way of electrodes strategically placed on the skin of the lower back.

31 Jul 2015

IUPUI researchers receive NIH grant to study effect of depression treatment on cardiovascular disease

Indiana University-Purdue University Indianapolis researchers led by Jesse Stewart of the School of Science, have received a $2.6 million grant from the National Institutes of Health to conduct the first randomized controlled trial to determine whether depression treatment can help prevent the development of cardiovascular disease.

31 Jul 2015

Pharmacist-included medical care teams help patients better control blood pressure

If you have hypertension, it pays to include a pharmacist in a medical care team. That's the upshot from research by the University of Iowa that found patients with uncontrolled hypertension had better blood pressure control when being cared for by pharmacists working in care teams (with a physician, for example) than patients who relied mostly on a doctor for medication guidance.

31 Jul 2015

Commonly prescribed drug also lowers blood pressure when combined with diuretic

With the growth of electronic medical records, research utilizing data from a large number of patients, known as big data studies, can provide important information which may be unattainable via clinical trials which tend to be costly, time-consuming and involve fewer patients.

30 Jul 2015

Bioenergetic analysis of pancreatic beta-cells shows impaired metabolic signature in type 2 diabetes patients

Impaired activation of mitochondrial energy metabolism in the presence of glucose has been demonstrated in pancreatic beta-cells from patients with type 2 diabetes. The cause of this dysfunction has been unknown. Publishing online in Endocrinology, Buck Institute assistant research professor Akos Gerencser, PhD, shows that in patients with type 2 diabetes the balance between supply and demand of the mitochondrial membrane potential (ΔψM) is altered causing a decrease in the signaling that turns on insulin secretion.

30 Jul 2015

Finding by UCSF researchers could increase availability of kidneys for transplant

Mild hypothermia in deceased organ donors significantly reduces delayed graft function in kidney transplant recipients when compared to normal body temperature, according to UC San Francisco researchers and collaborators, a finding that could lead to an increase in the availability of kidneys for transplant.

30 Jul 2015

Study reveals new way to help medical students learn about Alzheimer's disease

With the growing number of people with Alzheimer's disease, understanding their care is vital for doctors. Yet medical students often just learn the facts and may only see people with advanced disease who are at the hospital or nursing home. A study shows a new way to help medical students learn about the disease—at the art museum.

30 Jul 2015

Natural protein fragment produced in the brain can inhibit enzyme implicated in Alzheimer's disease

For the first time, UCLA researchers have shown that a natural protein fragment produced in the brain can act as an inhibitor of a key enzyme implicated in the onset of Alzheimer's disease, a finding that could lead to the development of new drugs to treat the disease.

30 Jul 2015

AAN's Behavioral Neurology Section Group provides recommendations for improving clinical cognitive testing

Recommendations for improving clinical cognitive testing were reported by the American Academy of Neurology's Behavioral Neurology Section Group, led by Kirk R. Daffner, MD, of Boston, Mass. The Group focused on the Neurobehavioral Status Exam (NBSE), conducting evidence-based reviews of testing used for five domains - attention, language, memory, spatial cognition, and executive function).

29 Jul 2015

Codman Neuro introduces new platform of embolic coils for treatment of brain aneurysms

Codman Neuro, part of DePuy Synthes Companies of Johnson & Johnson, has introduced a new platform of embolic coils for the treatment of brain aneurysms, supported by an enhanced detachment system designed to improve microcatheter stability and provide an optimized detachment zone for coils.

29 Jul 2015

UC Davis health economists predict total costs of caring for individuals with ASD in the U.S.

UC Davis health economists have for the first time projected the total costs of caring for all people with autism spectrum disorder (ASD) in the U.S. for the current calendar year and in 10 years if effective interventions and preventive treatments for the condition are not identified and widely available.

29 Jul 2015

Stroke News and Research

Further Reading

Cryptogenic stroke frequent and recurrent

IP10 levels linked to HBsAg decline during TDF treatment

Baseline HBsAg, platelet count predict spontaneous HBsAg seroclearance

Genotype A HBV mapped in acute, chronic Japanese patients

Researchers discover how neurons help learn new motor skills

Study provides mechanism for EDNRB gene's role in adaptation to life at high altitudes

MD Anderson scientists reveal role of metabolic enzyme fumarase in DNA repair

Researchers uncover strong evidence for genetic causes of cerebral palsy

Atomic level images reveal how neuropeptide hormone neurotensin may activate its receptors

New non-invasive spinal cord stimulation helps paralyzed men voluntarily move their legs

IUPUI researchers receive NIH grant to study effect of depression treatment on cardiovascular disease

Pharmacist-included medical care teams help patients better control blood pressure

Commonly prescribed drug also lowers blood pressure when combined with diuretic

Bioenergetic analysis of pancreatic beta-cells shows impaired metabolic signature in type 2 diabetes patients

Finding by UCSF researchers could increase availability of kidneys for transplant

Study reveals new way to help medical students learn about Alzheimer's disease

Natural protein fragment produced in the brain can inhibit enzyme implicated in Alzheimer's disease

AAN's Behavioral Neurology Section Group provides recommendations for improving clinical cognitive testing

Codman Neuro introduces new platform of embolic coils for treatment of brain aneurysms

UC Davis health economists predict total costs of caring for individuals with ASD in the U.S.

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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