Clinical Trial News and Research

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Virtual tissue technology helps identify new drug target to combat polycystic kidney disease

Using virtual tissue technology, researchers at Indiana University have identified a potential new drug target in the fight against polycystic kidney disease, an illness with no effective FDA-approved treatment that affects 200,000 people per year in the United States.

28 Jun 2016

Why does appetite loss occur during illness? An interview with Prof. Conti and Prof. Francesconi

Appetite, as a word, come from the Latin appetitus, meaning "desire for.” Therefore, appetite can be defined as a pleasurable sensation or the desire to eat. This sensation is coordinated by several brain areas associated with reward processing such amygdala, hippocampus, ventral pallidum, nucleus accumbens and striatum, and others.

28 Jun 2016

Researchers receive grant to improve quality of donor limb, tissue for transplant

A Case Western Reserve University School of Medicine faculty member has received $998,500 from the U.S. Department of Defense to develop a new approach to improve the quality and quantity of limbs and tissues obtained from brain dead organ donors.

27 Jun 2016

ESCMID-ASM conference aims to speed up drug development processes for drug-resistant infections

The European Society of Clinical Microbiology and Infectious Diseases and the American Society for Microbiology (ASM) are jointly organizing a conference in Vienna from 21 – 23 September 2016 to help researchers accelerate the development of new antimicrobials for drug-resistant infections.

27 Jun 2016

Federal government continues to ban valid scientific research on medicinal use of Cannabis sativa

The use of medical marijuana for millions of patients suffering from a wide range of health conditions and the subsequent therapeutic benefits has long been documented.

25 Jun 2016

Study highlights lack of guidance on deintensifying diabetic regimens

Patients with Type 2 diabetes often receive unnecessarily intensive treatment for long durations, increasing their risk of severe hypoglycaemia, research shows.

25 Jun 2016

Broccoli sprout extract may help prevent cancer recurrence in head and neck cancer survivors

Potent doses of broccoli sprout extract activate a "detoxification" gene and may help prevent cancer recurrence in survivors of head and neck cancer, according to a trial by the University of Pittsburgh Cancer Institute, partner with UPMC CancerCenter, confirming preliminary results presented last year at the American Association for Cancer Research Annual Meeting.

24 Jun 2016

SLU to conduct human clinical trial of vaccine to protect people from Zika virus

Saint Louis University's vaccine center has been tapped by the National Institutes of Health to conduct a human clinical trial of a vaccine to prevent the Zika virus, which can cause devastating birth defects in babies.

24 Jun 2016

Study compares efficacy of SDF in arresting root caries in elders from different fluoridated areas

On June 24, 2016, at the 94th General Session & Exhibition of the International Association for Dental Research, researcher Edward Lo, University of Hong Kong, SAR, China, will present a study titled "Effectiveness of SDF in Arresting Root Caries in Different Fluoridated Areas."

24 Jun 2016

Could artificial intelligence help to combat stress? An interview with Davide Morelli

Stress is actually a bit of a buzzword. The initial definition was “the reaction to changes”, which is why you get stressed also when good things happen, hence the distinction between good stress, eustress, and bad stress, distress.

23 Jun 2016

Two gene variants provide clue to why some patients with PD respond well to rasagiline drug

Researchers have identified a gene variant which explains why some patients with Parkinson's Disease respond well to drug treatment and other do not.

23 Jun 2016

Novel combination therapy slows cancer growth in patients with advanced solid tumors

A phase 1 clinical trial testing a novel combination therapy developed by scientists at VCU Massey Cancer Center slowed the growth of cancer in the majority of trial participants, which were patients with advanced solid tumors.

22 Jun 2016

Real-world analysis questions very low LDL targets

Patients treated for hypercholesterolaemia in clinical practice may not derive additional benefit from very intensive statin treatment, say researchers.

22 Jun 2016

Protein-based CHD risk score developed

Researchers have screened over 1000 plasma proteins to develop a predictive score in patients with stable coronary heart disease.

22 Jun 2016

New CAR-based therapy using combined cancer target could be effective for solid tumors

Chimeric antigen receptors (CARs), engineered from a patient's own immune cells, have been successful for treating blood cancers, but using CARs for solid tumors has been limited by side effects to normal tissues containing the protein targeted by the engineered cells.

22 Jun 2016

VUMC researchers aim to decode genetic underpinnings of human immune system

Researchers at Vanderbilt University Medical Center this month began recruiting volunteers to participate in a clinical trial aimed at decoding the human "immunome," the genetic underpinnings of the immune system.

22 Jun 2016

Clinical trial finds pioglitazone drug safe and effective for NASH patients

Researchers have found that an existing diabetes drug can be used to halt progression of another disease that is a leading cause of liver transplants.

21 Jun 2016

Patient navigators could help improve comprehensive cancer screening rates among low-income, ethnic minorities

A clinical trial conducted by Massachusetts General Hospital investigators has found that the use of patient navigators - individuals who assist patients in receiving health care services - may improve comprehensive cancer screening rates among patient populations not likely to receive recommended screenings.

21 Jun 2016

Scientific paper supports concept of CarThera's intracranial ultrasound implant to disrupt blood-brain barrier

CarThera, a French company based at the Brain and Spine Institute, that designs and develops innovative ultrasound-based medical devices to treat brain disorders, today announces the publication in Science Translational Medicine of a scientific paper on initial successes in disrupting the blood-brain barrier (BBB) with the use of ultrasound.

20 Jun 2016

Nonopioid interventional options for chronic pain not covered by insurance in few U.S. states

Recent studies have shown significant therapeutic value from the use of high-frequency - 10,000 (HF-10) spinal cord stimulation (SCS) for patients experiencing chronic back and leg pain.

20 Jun 2016

Clinical Trial News and Research

Virtual tissue technology helps identify new drug target to combat polycystic kidney disease

Why does appetite loss occur during illness? An interview with Prof. Conti and Prof. Francesconi

Researchers receive grant to improve quality of donor limb, tissue for transplant

ESCMID-ASM conference aims to speed up drug development processes for drug-resistant infections

Federal government continues to ban valid scientific research on medicinal use of Cannabis sativa

Study highlights lack of guidance on deintensifying diabetic regimens

Broccoli sprout extract may help prevent cancer recurrence in head and neck cancer survivors

SLU to conduct human clinical trial of vaccine to protect people from Zika virus

Study compares efficacy of SDF in arresting root caries in elders from different fluoridated areas

Could artificial intelligence help to combat stress? An interview with Davide Morelli

Two gene variants provide clue to why some patients with PD respond well to rasagiline drug

Novel combination therapy slows cancer growth in patients with advanced solid tumors

Real-world analysis questions very low LDL targets

Protein-based CHD risk score developed

New CAR-based therapy using combined cancer target could be effective for solid tumors

VUMC researchers aim to decode genetic underpinnings of human immune system

Clinical trial finds pioglitazone drug safe and effective for NASH patients

Patient navigators could help improve comprehensive cancer screening rates among low-income, ethnic minorities

Scientific paper supports concept of CarThera's intracranial ultrasound implant to disrupt blood-brain barrier

Nonopioid interventional options for chronic pain not covered by insurance in few U.S. states

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