Cancer Therapy News and Research

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Microbial ecosystems influence success of cancer checkpoint immunotherapy

Immune checkpoint inhibitors targeting PD-1 and PD-L1 have revolutionized cancer therapy, delivering long-term survival benefits in several malignancies.

9 Mar 2026

DNA nanomachine strategy reverses chemoresistance in small cell lung cancer

Professor Chao Zhang's team at Zhujiang Hospital, Southern Medical University, has developed a novel DNA nanomachine-based drug delivery and release strategy aimed at overcoming chemoresistance in small cell lung cancer (SCLC).

6 Mar 2026

MSK uncovers how interacting mutations shield breast cancer

Researchers at Memorial Sloan Kettering Cancer Center (MSK) have made an important discovery about how genetic mutations in breast cancer patients can interact and drive resistance to certain drugs called CDK4/6 inhibitors. This finding, published in Nature, suggests a new strategy for predicting and preventing resistance to specific therapies based on the tumor's genetic profile.

6 Mar 2026

A review of methionine dependency in modern cancer therapy

Methionine restriction (MR) has shown significant promise in cancer therapy because it targets the unique methionine dependency of many tumors. However, despite extensive research on MR, a clear synthesis of preclinical findings and their translation into clinical settings is lacking. This review aims to address this gap by consolidating existing evidence, identifying challenges, and highlighting opportunities for advancing MR as a viable cancer treatment strategy.

6 Mar 2026

Inflammatory signals from vesicles increase cancer cell aggressiveness and invasiveness

Pro-inflammatory M1 macrophages involved in immune responses accelerate the progression of melanoma through the extracellular vesicles they secrete, a recent study from the University of Eastern Finland shows. The findings were published in Cell Communication and Signaling.

3 Mar 2026

Ochsner MD Anderson Cancer Center delivers Louisiana’s first TIL therapy for melanoma

Ochsner MD Anderson Cancer Center at The Gayle and Tom Benson Cancer Center in New Orleans announces a milestone in advanced cancer treatment, as the first institution in Louisiana to provide an adult patient with tumor-infiltrating lymphocytes (TIL) therapy for advanced melanoma.

23 Feb 2026

Distinct gut toxicity patterns emerge with targeted cancer treatments

A new paper was published in Volume 13 of Oncoscience on February 6, 2026, titled "Gastrointestinal toxicity of targeted cancer therapies in the United States: Clinicopathologic patterns, FDA safety frameworks, and implications for national patient protection."

20 Feb 2026

Remote-controlled CAR T cells offer safer cancer therapy

Among the most promising tools of cancer therapy, engineered immune cells known as chimeric antigen-receptor (CAR) T cells have already transformed the treatment of blood cancers.

19 Feb 2026

Polyploidy-induced senescence may influence aging and cancer risk

A new editorial was published in Volume 18 of Aging-US on February 8, 2026, titled "Polyploidy-induced senescence: Linking development, differentiation, repair, and (possibly) cancer?"

18 Feb 2026

Mayo Clinic collaborates with New Phase Ltd. to install magnetic nanoparticle hyperthermia machine for cancer research

Mayo Clinic collaborated with New Phase Ltd. to install the first magnetic nanoparticle-mediated hyperthermia machine for cancer research in the U.S.

17 Feb 2026

Engineered Listeria boosts innate immunity against cancer

After nearly 40 years of research on how Listeria bacteria manipulate our cells and battle our immune system to cause listeriosis, Daniel Portnoy and his colleagues have discovered a way to turn the bacteria into a potent booster of the immune system - and a potential weapon against cancer.

13 Feb 2026

Tumor-targeted chimeric drug increases efficacy and limits side effects

Wistar scientists have combined a promising cancer therapy with a molecule that targets tumors to treat cancer more effectively.

7 Feb 2026

RNA micelles enable targeted chemotherapy without immune toxicity

A new study in mice hints at the potential to use tiny particles made with RNA molecules to deliver chemotherapy drugs and other therapies directly to tumors, killing cancer cells without generating an immune response or toxicity-related side effects.

7 Feb 2026

Enhanced natural killer cells show promise for HIV remission

More than 30 million people with HIV must take antiretroviral therapy (ART) medications daily to keep the virus under control, according to the Joint United Nations Programme on HIV/AIDS (UNAIDS).

5 Feb 2026

Lower hinge of immunoglobulin G acts as a critical immune control hub

The lower hinge of immunoglobulin G (IgG), an overlooked part of the antibody, acts as a structural and functional control hub, according to a study by researchers at Science Tokyo.

31 Jan 2026

ERC Proof of Concept grant supports promising CRISPR-based cancer treatment research

Microbiologist John van der Oost of Wageningen University & Research (WUR) has received an ERC Proof of Concept grant to further develop a promising CRISPR-based approach to cancer treatment. With funding of €150,000, he and researcher Christian Südfeld will spend the next eighteen months working on a method to kill cancer cells from within, while sparing healthy cells as much as possible.

30 Jan 2026

Light-driven nanoparticles to target tumors

Researchers at NYU Abu Dhabi have developed a new light-based nanotechnology that could improve how certain cancers are detected and treated, offering a more precise and potentially less harmful alternative to chemotherapy, radiation, and surgery.

30 Jan 2026

Two-pronged therapeutic technology for cancer wins Pfizer Prize for Biomedical Research 2026

Whereas conventional treatments such as chemotherapy and radiotherapy show their limitations in battling certain advanced cancers, immunotherapy and therapeutic vaccines have opened up a new realm of hope for patients.

29 Jan 2026

New prognostic model improves survival prediction for spinal metastasis patients

Spinal metastasis, the spread of cancer to the spine, is a frequent complication in advanced cancer. It often causes severe pain and paralysis, significantly impacting quality of life.

27 Jan 2026

New trial tests strategies to protect heart health during prostate cancer therapy

City of Hope, one of the largest and most advanced cancer research and treatment organizations in the United States with its National Medical Center ranked among the nation's top cancer centers by U.S. News & World Report, has opened a phase 2 clinical trial comparing three different strategies for protecting heart health in prostate cancer patients who receive androgen deprivation therapy (ADT), a potentially lifesaving hormone therapy.

26 Jan 2026

Cancer Therapy News and Research

Microbial ecosystems influence success of cancer checkpoint immunotherapy

DNA nanomachine strategy reverses chemoresistance in small cell lung cancer

MSK uncovers how interacting mutations shield breast cancer

A review of methionine dependency in modern cancer therapy

Inflammatory signals from vesicles increase cancer cell aggressiveness and invasiveness

Ochsner MD Anderson Cancer Center delivers Louisiana’s first TIL therapy for melanoma

Distinct gut toxicity patterns emerge with targeted cancer treatments

Remote-controlled CAR T cells offer safer cancer therapy

Polyploidy-induced senescence may influence aging and cancer risk

Mayo Clinic collaborates with New Phase Ltd. to install magnetic nanoparticle hyperthermia machine for cancer research

Engineered Listeria boosts innate immunity against cancer

Tumor-targeted chimeric drug increases efficacy and limits side effects

RNA micelles enable targeted chemotherapy without immune toxicity

Enhanced natural killer cells show promise for HIV remission

Lower hinge of immunoglobulin G acts as a critical immune control hub

ERC Proof of Concept grant supports promising CRISPR-based cancer treatment research

Light-driven nanoparticles to target tumors

Two-pronged therapeutic technology for cancer wins Pfizer Prize for Biomedical Research 2026

New prognostic model improves survival prediction for spinal metastasis patients

New trial tests strategies to protect heart health during prostate cancer therapy

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