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Natural polyphenol boosts mitochondrial function and muscle performance during aging

Oleuropein enhances mitochondrial calcium uptake, reversing age-related declines in muscle function and energy metabolism, with promising clinical potential.

2 Dec 2024

How neural and hormonal gut-brain communication shapes metabolism and health

Interoception research reveals how gut-brain communication via neural, hormonal, and microbial pathways regulates metabolism, hunger, and overall health, offering insights for therapeutic innovations.

25 Nov 2024

Ablation may offer better outcomes than medication for ventricular tachycardia

Ablation, a procedure to treat abnormal electrical short circuits caused by a heart attack and is usually reserved for patients who do not improve with medication, may be a better first-line treatment for heart attack survivors experiencing dangerous rapid heartbeat episodes, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.

18 Nov 2024

New oral painkiller developed for chronic abdominal pain

University of Queensland researchers have developed a new class of oral painkillers to suppress chronic abdominal pain that is based on the peptide hormone oxytocin that drives childbirth contractions.

18 Nov 2024

Vanderbilt receives $3.3 million grant to develop medications for preventing preterm birth

Vanderbilt University Medical Center is receiving $3.3 million over two years through the Advanced Research Projects Agency for Health's (ARPA-H) Sprint for Women's Health for its early-stage research efforts to develop medications designed to suppress premature uterine contractions during pregnancy.

15 Nov 2024

Research unveils method for defibrillation using less energy

In a paper published this week in Chaos, by AIP Publishing, researchers from Sergio Arboleda University in Bogotá, Colombia, and the Georgia Institute of Technology in Atlanta used an electrophysiological computer model of the heart's electrical circuits to examine the effect of the applied voltage field in multiple fibrillation-defibrillation scenarios.

5 Nov 2024

New device enables real-time monitoring of stem cell growth

Unlike most cells in the human body, stem cells have the unique ability to divide indefinitely. This unique property makes them especially appealing to scientists exploring ways to extend human lifespans or develop new methods for repairing damaged tissues.

30 Oct 2024

Immunotherapy may be an effective treatment strategy for heart failure

A new study from Washington University School of Medicine in St. Louis suggests that a type of immunotherapy - similar to that approved by the Food and Drug Administration (FDA) to treat inflammatory conditions such as arthritis - also may be an effective treatment strategy for heart failure.

23 Oct 2024

New protein shows potential for treating systolic heart failure

The heart is a muscle like no other, beating 60 to 100 times per minute on average, around the clock. But when it grows weak, it can lead to serious problems: from debilitating shortness of breath and swelling in the legs and feet, to fluid in the lungs and even death.

16 Oct 2024

Study: People with a sweet tooth at higher risk of developing depression, diabetes, and stroke

People with a preference for sweets are at a higher risk of developing depression, diabetes, and suffering a stroke, according to new research from the University of Surrey.

9 Oct 2024

Study paves way for revolutionizing the management of muscle disorders

The type 1 ryanodine receptor (RyR1) is an important calcium release channel in skeletal muscles essential for muscle contraction.

18 Sep 2024

Soft drinks worsen menstrual pain, study shows

Soft drink intake is linked to a higher likelihood and severity of primary dysmenorrhea in Chinese women, especially in rural areas, while moderate coffee consumption may reduce PD severity.

16 Sep 2024

By-products from olive oil production show promise for preventing cardiovascular disease, study shows

A study reveals olive oil wastewater extract enriched with hydroxytyrosol shows promise in preventing cardiovascular diseases through antioxidant properties.

10 Sep 2024

Cosmochemistry techniques shed light on potential new Alzheimer's disease biomarker

The study identifies lower potassium isotope ratios in Alzheimer's patients, suggesting δ41K as a viable biomarker for early detection of the disease.

9 Sep 2024

Breakthrough technique enables clear visualization of organs in the body

Researchers have developed a new way to see organs within a body by rendering overlying tissues transparent to visible light.

6 Sep 2024

New insights into stiff-person syndrome, advancing diagnosis and treatment

Research explores the complexities of diagnosing and treating stiff-person syndrome, emphasizing the uncertain role of GAD antibodies and the promise of novel therapies.

5 Sep 2024

Understanding the origins of spontaneous neural activity

A new study, published in Nature Communications this week, led by Jake Gavenas PhD, while he was a PhD student at the Brain Institute at Chapman University, and co-authored by two faculty members of the Brain Institute, Uri Maoz and Aaron Schurger, examines how the brain initiates spontaneous actions. In addition to demonstrating how spontaneous action emerges without environmental input, this study has implications for the origins of slow ramping of neural activity before movement onset - a commonly-observed but poorly understood phenomenon.

5 Sep 2024

Scientists find way to restore brain's self-cleaning function

Alzheimer's, Parkinson's, and other neurological disorders can be seen as "dirty brain" diseases, where the brain struggles to clear out harmful waste. Aging is a key risk factor because, as we grow older, our brain's ability to remove toxic buildup slows down. However, new research in mice demonstrates that it's possible to reverse age-related effects and restore the brain's waste-clearing process.

16 Aug 2024

Study highlights predictors of cognitive decline in early Alzheimer's disease

Older age, female sex, irregular heart rhythms, and daily activity levels can help to predict how much Alzheimer's Disease patients' cognitive function will decline, and how much they will depend on their caregivers over the next two years.

14 Aug 2024

High-frequency eccentric resistance training decreases passive muscle stiffness

Resistance, or weight training, is widely recommended in sports and rehabilitation as an effective exercise to increase muscular strength and size. This form of exercise involves applying resistance to muscle contraction to build strength. However, some practitioners believe resistance training can increase passive muscle stiffness over time.

1 Aug 2024