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New microfluidic device brings affordable kidney testing to the point of care

Chronic kidney disease (CKD) affects over 800 million people globally and is often diagnosed too late for effective intervention.

31 May 2025

Pentoxifylline offers no survival benefit for severe alcohol-associated hepatitis

Severe alcohol-associated hepatitis (sAH) remains a highly lethal condition with limited therapeutic options. Characterized by rapid liver decompensation, sAH is often accompanied by acute kidney injury (AKI), a complication that substantially worsens prognosis.

13 May 2025

How urine caffeine levels may help detect diabetic eye damage early

Researchers found that higher urinary levels of caffeine and specific metabolites, especially in men, were significantly associated with diabetic retinopathy risk. The cross-sectional study used NHANES 2009–2014 data and highlights potential biomarkers for early detection in diabetic populations.

7 May 2025

Low testosterone linked to higher kidney stone risk in men, study finds

A large cross-sectional study in South Korea found that men with low testosterone levels (below 3.33 ng/mL) were significantly more likely to have kidney stones. This association held even after adjusting for age and metabolic risk factors, suggesting testosterone may play a protective role.

6 May 2025

N-acetylcysteine protects against acyclovir-induced nephrotoxicity

Oxidative stress could be a key process in acyclovir (ACV)-induced nephrotoxicity. N-acetylcysteine (NAC) is a water-soluble antioxidant with anti-inflammatory activity.

18 Apr 2025

Vitamin C from fresh foods helps lower heart disease risk in type 2 diabetes

Low vitamin C levels are linked to higher cardiovascular disease prevalence in people with type 2 diabetes. Fresh fruit and vegetable intake is associated with higher vitamin C levels and may offer protective cardiovascular effects.

7 Apr 2025

Tirzepatide improves kidney, cardiovascular function in patients with obesity and HFpEF

The drug tirzepatide improved kidney function and cardiovascular outcomes among patients with obesity and heart failure with preserved ejection fraction (HFpEF) compared with placebo at one year, according to featured clinical research presented at the American College of Cardiology's Annual Scientific Session (ACC.25) and simultaneously published in JACC.

31 Mar 2025

Six promising biomarkers could improve early and accurate detection of kidney injury

Critical Path Institute® (C-Path) and Boston Medical Center (BMC) published results for six biomarkers that could improve the early and accurate detection of kidney injury, leading to both the development of safer medications and better health outcomes for all patients.

28 Mar 2025

Advances in organ preservation techniques and future prospects

A review article published in Engineering delves into the crucial field of organ preservation, exploring its history, current techniques, and future prospects.

14 Mar 2025

Glucarpidase shows promise in treating kidney toxicity from methotrexate

An FDA-approved medication called glucarpidase could serve as an antidote to kidney toxicity in patients receiving the chemotherapy drug methotrexate (MTX), according to a new study by investigators at Mass General Brigham.

6 Jan 2025

New biomarkers may offer a more sensitive approach for monitoring kidney health

Drug-induced kidney injury, or nephrotoxicity, is a common complication in clinical medicine that happens when drugs damage the kidneys.

6 Jan 2025

Semaglutide reduces urine albumin-to-creatinine ratio in overweight chronic kidney disease patients

Researchers investigate the clinical efficacy of semaglutide in controlling urine albumin-to-creatinine ratio in overweight patients with chronic kidney disease.

31 Oct 2024

Ozempic effective for patients with chronic kidney damage

In a 24-week trial, semaglutide led to a 52% reduction in albuminuria and improved kidney health in individuals with chronic kidney disease and obesity.

28 Oct 2024

Long-term air pollution exposure linked to increased risk of acute kidney injury and mortality

Prolonged exposure to air pollutants like PM2.5 and nitrogen oxides significantly raises acute kidney injury risk and related mortality, urging policy action.

24 Oct 2024

A review of clinical features, diagnosis, and management of Mpox

A comprehensive review in JAMA outlines monkeypox's clinical presentation and management, stressing the need for increased surveillance and vaccination efforts.

17 Oct 2024

Study uncovers hidden proteins fueling heart disease and stroke

Researchers identified key proteins linked to cardiovascular disease, highlighting new targets for drug development using genetic and observational analyses in UK and China biobanks.

26 Sep 2024

Understanding the role of TIPS in improving renal function amid cirrhosis

Cirrhosis is one of the leading causes of mortality from non-communicable diseases, with complications arising as liver function deteriorates.

26 Sep 2024

X-rays with gold nanoparticles improve kidney disease detection over standard blood tests

In a study published July 29 in Advanced Materials, University of Texas at Dallas researchers found that X-rays of the kidneys using gold nanoparticles as a contrast agent might be more accurate in detecting kidney disease than standard laboratory blood tests.

20 Sep 2024

Breakthrough metabolomic aging score that predicts mortality better than traditional methods

Researchers developed a metabolomic aging score using NMR biomarkers that predicts short-term mortality and disease risk more accurately than other aging metrics.

16 Sep 2024

Research highlights cardiovascular benefits of semaglutide for overweight adults with impaired kidney function

The anti-obesity medication semaglutide may help to prevent heart attacks, strokes, and other major adverse cardiovascular events (MACE) as well as death in adults with overweight or obesity who don't have diabetes, whether or not they also have impaired kidney function, according to new research to be presented at this year's Annual Meeting of The European Association for the Study of Diabetes (EASD), Madrid (9-13 Sept).

13 Sep 2024