Cytoplasm News and Research

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Exosome-mediated siRNA delivery targets antibiotic resistance in bacteria

Multidrug-resistant bacteria pose a major threat to human health. Manipulation of bacterial genes at the transcriptional level is a potential strategy to fight antibiotic-resistant bacterial infections by silencing their resistance genes.

7 Mar 2025

Breakthrough discovery offers hope for more effective malaria treatment

Antimalarial drug resistance is a pressing issue in combating the spread of malaria worldwide. In a new study, researchers from Children's Hospital of Philadelphia (CHOP) discovered a key process where malarial parasites take up a human blood cell enzyme, which could provide a new approach for antimalarial treatment.

6 Mar 2025

Novel strategy targets beta cell dysfunction in type 2 diabetes

Researchers from the Icahn School of Medicine at Mount Sinai in New York have discovered a novel approach to protecting insulin-producing beta cells from the damaging effects of glucolipotoxicity-a harmful condition linked to the progression of type 2 diabetes (T2D).

4 Mar 2025

Study unveils protein complex critical for sperm morphology

The human body is full of checks and balances that ensure correct growth, development, and function of all our different systems. Now, researchers from Japan have reported a newly discovered protein interaction that regulates sperm development.

3 Mar 2025

Novel therapeutic approaches targeting the Wnt pathway in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the deadliest cancers globally, with increasing incidence and mortality rates.

19 Feb 2025

ASU researchers propose a unifying explanation for molecular chaos driving Alzheimer's disease

In a groundbreaking theory, scientists at Arizona State University's Biodesign Institute propose a unifying explanation for the molecular chaos driving Alzheimer's disease.

6 Feb 2025

New insights into how cells clean and recycle waste

A recent study from Tata Institute of Fundamental Research, Mumbai, India has revealed new details about how our cells clean up and recycle waste.

21 Jan 2025

Study unveils role of TLE6 in male sperm development

Infertility is a major global challenge associated with physiological and psychological impact. Genetic mutations that affect early embryonic development, oocyte (egg cell) maturation, and fertilization have recently been studied as causes of infertility.

16 Jan 2025

Targeting miR-4274 and PEX5 can help overcome radioresistance in colorectal cancer

Colorectal cancer (CRC) is a global health concern, and despite advances in radiotherapy, endogenous radioresistance in CRC patients remains a challenge.

9 Jan 2025

Nuclear lipid droplets could play a key role in aging and disease

A new research perspective was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 22 on December 9, 2024, entitled "Nuclear lipid droplets: a novel regulator of nuclear homeostasis and aging."

7 Jan 2025

Exploring new ways to improve treatment options for kidney cancer patients

A Medical University of South Carolina Hollings Cancer Center researcher is exploring new ways to improve treatment options for kidney cancer patients.

30 Dec 2024

New strategy revolutionizes glycoproteomics research

Protein glycosylation is a fundamental biological process that regulates various cellular functions, yet its study has been hampered by the complexity and low abundance of glycoproteins.

26 Dec 2024

A new era of targeted therapy with antibody–drug conjugates

TBC

From Sino Biological Inc. 16 Dec 2024

Advanced microscopy reveals how ribosomes attach to mRNA for protein synthesis

Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called mRNA.

28 Nov 2024

Novel mRNA-based therapy offers hope for patients with proliferative vitreoretinopathy

A new preclinical study by Mass Eye and Ear investigators showed that a novel mRNA-based therapy may be able to prevent blindness and scarring from proliferative vitreoretinopathy (PVR) following a retinal detachment repair or traumatic injury to the eye.

27 Nov 2024

Metabolic enzymes take on unexpected roles in cell division and DNA repair

Researchers at the Centre for Genomic Regulation (CRG) reveal that metabolic enzymes known for their roles in energy production and nucleotide synthesis are taking on unexpected "second jobs" within the nucleus, orchestrating critical functions like cell division and DNA repair.

12 Nov 2024