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AI-enabled stethoscope doubles detection of valvular heart disease

New research shows that the use of an AI-enabled digital stethoscope more than doubled the identification of moderate to severe valvular heart disease during routine clinical examinations, compared to a traditional stethoscope.

5 Feb 2026

Antibody-producing plasma cells shape effectiveness of PD-1 immunotherapy

Scientists at the Icahn School of Medicine at Mount Sinai have identified an important immune response that helps explain why some cancer patients benefit from immunotherapy while others do not.

27 Jan 2026

MRI measures of glymphatic activity may improve noninvasive intracranial hypertension diagnosis

A new study led by investigators from Mass General Brigham shows that a brain waste- "clean-up" system is influenced by intracranial pressure.

27 Jan 2026

Trojan horse immunotherapy opens tumors to immune system attack

Scientists at the Icahn School of Medicine at Mount Sinai have developed an experimental immunotherapy that takes an unconventional approach to metastatic cancer: instead of going after cancer cells directly, it targets the cells that protect them.

22 Jan 2026

Cancer vaccines enter a new era of personalized immunotherapy

A new comprehensive review from researchers at the Icahn School of Medicine at Mount Sinai details how decades of cancer vaccine research are converging into a new era of more precise, personalized, and effective immunotherapies, particularly when combined with other cancer treatments.

22 Jan 2026

Steady decline in antibiotics for childhood respiratory infections

Norwegian study finds reduced antibiotic use for childhood respiratory infections, yet high prescriptions for ear infections call for improved guidelines.

13 Jan 2026

Trial finds no benefit of anti-inflammatory therapy in trachomatous trichiasis surgery

John Kempen, MD, MPH, PhD, MHS, Director of Epidemiology for Ophthalmology at Mass Eye and Ear and Harvard Medical School, is the lead author of a paper published in The Lancet Global Health, "Evaluation of fluorometholone as adjunctive medical therapy for trachomatous trichiasis surgery (FLAME): a parallel, double-blind, randomised controlled field trial in the Jimma Zone, Ethiopia."

12 Jan 2026

Single-cell analysis illuminates myeloma immune landscape

Scientists at the Icahn School of Medicine at Mount Sinai, in partnership with the Multiple Myeloma Research Foundation (MMRF) and in collaboration with leading institutions across the country, have helped generate the largest single-cell immune cell atlas of the bone marrow in patients with multiple myeloma, a blood cancer that, while treatable, remains incurable.

9 Jan 2026

Study sheds light on rare emotional and physical responses during orgasm

When some women orgasm, they experience unusual physical and emotional responses such as laughing, crying, headaches, tingling, foot pain, nosebleeds and more.

5 Jan 2026

New insights into the global expansion of Candida auris

The fungal species Candida auris is spreading across the globe, and gaining in virulence, according to a new review by a Hackensack Meridian Center for Discovery and Innovation (CDI) scientist and colleagues.

30 Dec 2025

Rethinking Mendelian assumptions in inherited retinal degenerations

A new study challenges what's long been assumed about genetic variants thought to always cause inherited blindness.

22 Dec 2025

Early identification of nutrition risk in ICU patients using artificial intelligence

A new study by researchers at the Icahn School of Medicine at Mount Sinai suggests that artificial intelligence (AI) could help predict which critically ill patients on ventilators are at risk of underfeeding,

22 Dec 2025

First-of-its-kind mRNA system switches on therapeutic genes inside targeted cells

Researchers at the Icahn School of Medicine at Mount Sinai have developed a first-of-its-kind mRNA system that switches on therapeutic genes preferentially inside targeted cells-an advance demonstrated in studies in mice that could lay the groundwork for safer, more precise treatments for cancer and other diseases.

16 Dec 2025

Novel AI tool not only identifies genetic mutations but also predicts the type of disease

Scientists at the Icahn School of Medicine at Mount Sinai have developed a novel artificial intelligence tool that not only identifies disease-causing genetic mutations but also predicts the type of disease those mutations may trigger.

15 Dec 2025

SIRT3 deficiency worsens eustachian tube dysfunction during middle-ear infection

Middle-ear infections caused by Gram-negative bacteria remain among the most common pediatric illnesses worldwide.

9 Dec 2025

Timing of genetic mutation dictates childhood leukemia aggressiveness

A team of researchers at the Icahn School of Medicine at Mount Sinai has uncovered why children with the same leukemia-causing gene mutation can have dramatically different outcomes: it depends on when in development the mutation first occurs.

8 Dec 2025

Tracing the diverse global pathways of migrant nurses

SMU Office of Research Governance & Administration – Associate Professor Yasmin Ortiga chats with Filipino nurses for a living. The sociologist at Singapore Management University (SMU) tends to ask them about their hopes and dreams, why they uprooted themselves to go work in a hospital miles away from their home in the Philippines, often leaving young children behind.

28 Nov 2025