Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

New research highlights hidden metabolic risks in non-obese HIV patients

A new UC San Francisco study helps explain why people with HIV remain at elevated risk for type 2 diabetes despite effective suppression of the virus with modern medications.

6 Aug 2026

Versatile receptor protein plays critical role in regulating tissue repair

A comprehensive new review highlights the expanding importance of Lgr6, a member of the G protein-coupled receptor family, as a critical regulator of tissue homeostasis, injury repair, and disease development across multiple organ systems.

5 Aug 2026

Insilico Medicine highlights AI-powered biological target discovery for rare sinonasal cancer

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven biotechnology company, today announced the publication of a collaborative study in the journal npj Precision Oncology.

4 Aug 2026

Researchers suggest a potential therapeutic strategy for muscle loss associated with obesity

Obesity has been linked to skeletal muscle loss and deterioration. While M2 macrophages may play a role in regulating muscle function, the underlying mechanisms remain poorly understood.

4 Aug 2026

Child-friendly lung test identifies subtle abnormalities before stem cell transplant

As spirometry requires coordinated deep breathing and can be challenging for children to perform, researchers from the USA, as part of the TRANSPIRE study investigating lung complications in children undergoing hematopoietic stem cell transplantation (HSCT), explored the potential of oscillometry, a simple and child-friendly lung function test.

3 Aug 2026

Texas A&M study links polyethylene microplastics to fatty liver disease

Microplastics have become nearly impossible to avoid. They have been detected in oceans, drinking water and even the human body, but scientists are still uncovering how they affect human health.

3 Aug 2026

Using DNA sequencing for accurate identification of microbial infections in cystic fibrosis patients

Lung infections are a constant risk for people living with cystic fibrosis (CF), a life-threatening genetic disorder which impairs lung function, predisposes people to persistent airway infections and exposes them to acquiring multidrug resistant infections.

3 Aug 2026

Daily tomatoes lowered a key marker of liver fat in MASLD trial

An exploratory randomized trial found that 200 g of raw tomatoes plus 50 g of tomato sauce daily for six weeks produced a greater reduction in CAP-defined hepatic steatosis than a tomato-free diet in adults with MASLD. The improvement occurred without major weight or metabolic changes, but larger and longer trials are needed to confirm its clinical significance.

2 Aug 2026

Traditional Japanese medicine for obesity may help reduce age-related tissue fibrosis

A traditional Japanese medicine used for obesity may do more than support weight loss. Researchers at the University of Osaka, working with Kobayashi Pharmaceutical Co., Ltd. investigated whether Bofutsushosan could protect aging tissues from fibrosis - the excessive buildup of scar-like tissue that can make organs stiff and less functional.

2 Aug 2026

AI-powered blood test detects liver cancer across distinct populations

Researchers at the Johns Hopkins Kimmel Cancer Center validated an artificial intelligence (AI)-powered blood test that accurately detected liver cancer in people from two geographically and biologically distinct populations and also uncovered the underlying biological signals that make the test effective.

31 Jul 2026

NIH funds UVA research to develop advanced laboratory tissue models

A University of Virginia researcher has received a five-year, $2.1 million National Institutes of Health grant to develop advanced laboratory tissue models that could improve drug testing, deepen scientists' understanding of disease and reduce the need for animal testing.

30 Jul 2026

Insilico unveils standardized evaluation framework to validate AI-driven drug discovery models

As general-purpose and domain-specific AI models rapidly infiltrate drug discovery, one critical question looms over the pharmaceutical sector: Can these models actually discover drugs, or are they just good at taking tests?

30 Jul 2026

Microbial metabolites could help improve functional cure rates for hepatitis B

Chronic hepatitis B (CHB) remains a major global challenge. Current therapies suppress HBV but rarely achieve functional cure (sustained HBsAg loss).

30 Jul 2026

Qureight closes $20 million Series B financing

Qureight, an end-to-end imaging company that provides enterprise-grade imaging and precision endpoints for clinical trials with a focus on lung and heart disease, today announced it has raised $20 million in a Series B financing, led by Molten Ventures.

From Qureight 30 Jul 2026

FDA grants fast track designation to Insilico's AI-designed mesothelioma drug candidate

Insilico Medicine ("Insilico"; HKEX: 3696), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, today announced that ISM6331, a novel, potential best-in-class pan-TEAD inhibitor driven by Insilico's proprietary AI, has received Fast Track Designation (FTD) from the U.S.

29 Jul 2026

A common dietary nutrient feeds a gut pathway linked to atrial fibrillation

Researchers linked higher plasma TMAO to prevalent atrial fibrillation in 5,090 people and found that TMAO or choline supplementation accelerated AF onset, progression, atrial remodeling, and electrical dysfunction in mice. Inhibiting gut microbial TMA production lowered circulating TMAO and delayed AF in mice, identifying a potential therapeutic pathway that now requires human testing.

27 Jul 2026

New model holds promise as a non-invasive, low-cost tool for MAFLD screening

Metabolic dysfunction-associated fatty liver disease (MAFLD) represents a predominant cause of chronic liver disease, underscoring the demand for accessible, non-invasive diagnostic tools.

23 Jul 2026

Study reveals unexpected mechanism driving extreme antibiotic resistance

A patient with a severe infection is prescribed a potent antibiotic. Hopes for improvement are high, but just after treatment is given, resistance to the drug increases thousands of times. How could this happen?

23 Jul 2026

Emerging PPAR therapies offer new hope for primary biliary cholangitis

Primary biliary cholangitis is a rare autoimmune disease that affects the liver and can progress to cirrhosis. It occurs when the immune system attacks the small bile ducts within the liver. As a result, bile builds up, leading to inflammation and progressive liver damage. Although a first-line treatment exists, 40% of patients do not respond adequately to it or cannot tolerate it, so new treatment options need to be developed.

23 Jul 2026

AI platform uncovers promising target for chronic pain treatmen

Despite the widespread availability of analgesics, pain management remains one of the most significant and pervasive challenges in modern medicine, with more than 20% of the global population suffering from chronic pain, especially chronic neuropathic pain characterized by central sensitization.

22 Jul 2026

Fibrosis News and Research

Further Reading

New research highlights hidden metabolic risks in non-obese HIV patients

Versatile receptor protein plays critical role in regulating tissue repair

Insilico Medicine highlights AI-powered biological target discovery for rare sinonasal cancer

Researchers suggest a potential therapeutic strategy for muscle loss associated with obesity

Child-friendly lung test identifies subtle abnormalities before stem cell transplant

Texas A&M study links polyethylene microplastics to fatty liver disease

Using DNA sequencing for accurate identification of microbial infections in cystic fibrosis patients

Daily tomatoes lowered a key marker of liver fat in MASLD trial

Traditional Japanese medicine for obesity may help reduce age-related tissue fibrosis

AI-powered blood test detects liver cancer across distinct populations

NIH funds UVA research to develop advanced laboratory tissue models

Insilico unveils standardized evaluation framework to validate AI-driven drug discovery models

Microbial metabolites could help improve functional cure rates for hepatitis B

Qureight closes $20 million Series B financing

FDA grants fast track designation to Insilico's AI-designed mesothelioma drug candidate

A common dietary nutrient feeds a gut pathway linked to atrial fibrillation

New model holds promise as a non-invasive, low-cost tool for MAFLD screening

Study reveals unexpected mechanism driving extreme antibiotic resistance

Emerging PPAR therapies offer new hope for primary biliary cholangitis

AI platform uncovers promising target for chronic pain treatmen

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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