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Antiplatelet medications linked to worse outcomes in people hospitalized with a brain bleed

Analysis of hospital registry data found that people who were hospitalized due to bleeding in the brain and who had taken multiple antiplatelet medications, or medications stronger than aspirin, were more likely to die before leaving the hospital compared to those not taking any antiplatelet medication, according to a preliminary study to be presented at the American Stroke Association's International Stroke Conference 2026.

29 Jan 2026

Following the EAT-Lancet diet lowers chronic kidney disease risk

Research shows the EAT-Lancet diet may lower chronic kidney disease risk, emphasizing the importance of diet quality and personalized nutrition in prevention.

28 Jan 2026

Diverse exercise routines associated with reduced risk of death

Regularly doing a mix of different types of physical activity may be best for prolonging the lifespan, but the associations aren't linear, pointing to a possible optimal threshold effect, suggests research published in the open access journal BMJ Medicine.

20 Jan 2026

APOE gene: A major driver in Alzheimer's disease

Potentially more than 90% of Alzheimer's disease cases would not occur without the contribution of a single gene (APOE), according to a new analysis led by UCL researchers.

9 Jan 2026

Stopping weight loss drugs leads to rapid weight regain and health reversal

Stopping weight loss drugs is followed by weight regain and reversal of beneficial effects on heart and metabolic health markers such as high cholesterol and high blood pressure, finds a study published by The BMJ today.

7 Jan 2026

Experimental drug targets early toxic amyloid to slow Alzheimer’s disease

An experimental drug developed at Northwestern University has demonstrated further promise as an early intervention for Alzheimer's disease.

18 Dec 2025

High fructose intake increases fatty liver risk

Excessive fructose intake from soft drinks is linked to liver damage and NAFLD. Lifestyle modifications are essential for effective prevention and treatment.

16 Dec 2025

What happens to your body when you eat takeaway food too often?

This study of 8,556 US adults shows that frequent takeaway food consumption is associated with a higher energy-adjusted Dietary Inflammatory Index and adverse cardiometabolic markers. The findings suggest that reducing takeaway intake and lowering dietary inflammatory potential may improve long-term cardiometabolic health.

11 Dec 2025

Family history of cardiometabolic disease linked to early heart damage in adolescents

A new study among more than 1,500 British adolescents is the first in the world to assess the association between familial cardiometabolic diseases and the offspring's risk of premature heart damage by early adulthood.

10 Dec 2025

Recurrent strokes can be avoided with optimal prevention and follow-up

Patients who have had a stroke are prescribed medication to prevent new strokes. Nevertheless, fewer than half achieve the optimal treatment targets.

3 Dec 2025

CAR T cell therapy could be a highly effective tool against atherosclerosis

A pioneering preclinical study has shown that CAR T cell therapy-a personalized form of immunotherapy used in cancer treatment-could be a highly effective tool against atherosclerosis, the condition where a build-up of plaque in the arteries reduces blood flow, leading to heart attacks and strokes.

21 Nov 2025

Current genetic screening guidelines overlook most cases of familial hypercholesterolemia

Current genetic screening guidelines fail to identify most people with an inherited condition known as familial hypercholesterolemia that can cause dangerously high cholesterol and early heart disease, a Mayo Clinic study found.

19 Nov 2025

Income and social disparities found to influence dementia risk factors

People with lower incomes and people from racial and ethnic historically underrepresented groups in clinical studies are more likely to have modifiable risk factors for dementia, factors that could be changed to lower their risk, according to a study published November 12, 2025, in Neurology, the medical journal of the American Academy of Neurology.

12 Nov 2025

New data supports earlier use of evolocumab in high-risk diabetes

Adding the PCSK9 inhibitor evolocumab to a high-intensity, cholesterol-lowering regimen reduced the risk of a first major cardiovascular event among adults with atherosclerotic cardiovascular disease (ASCVD) or diabetes , according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

11 Nov 2025

New initiative boosts cholesterol control in veterans with heart and blood vessel disease

A quality improvement program helped reduce "bad cholesterol" (LDL or low-density lipoprotein) levels among military veterans who have heart and blood vessel disease, according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

One-time CRISPR therapy safely lowers cholesterol and triglycerides in early trial

In a 15-patient, Phase 1 one, first-in-human trial, a one-time, CRISPR-Cas9 gene-editing therapy safely reduced LDL cholesterol and triglycerides in people with difficult-to-treat lipid disorders, according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

PCSK9 inhibitor combined with a statin may help reduce LDL cholesterol after heart transplant

The cholesterol medication alirocumab, a PCSK9 inhibitor, combined with a statin appeared to reduce LDL cholesterol levels by more than 50% among patients after a heart transplant, according to a late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

Exploring cost-effective approaches to detecting familial hypercholesterolemia in children

In the United States, one in every 250 people has inherited a genetic variant that leads to dangerously high cholesterol levels from birth.

10 Nov 2025

People with traumatic spinal cord injuries at higher risk of developing chronic health problems

A new study by investigators from Mass General Brigham shows that patients with traumatic spinal cord injuries (TSCI) are at a higher risk of developing a myriad of chronic health problems, regardless of age, location of the injury and prior health status.

4 Nov 2025

First-of-its-kind resource created to identify people with genetic risk for elevated 'bad' cholesterol

An international team led by a University of Pittsburgh School of Medicine scientist has created a first-of-its-kind resource to identify those with a genetic risk for elevated 'bad' cholesterol -- a major contributor to heart disease.

30 Oct 2025

High Cholesterol News and Research

Antiplatelet medications linked to worse outcomes in people hospitalized with a brain bleed

Following the EAT-Lancet diet lowers chronic kidney disease risk

Diverse exercise routines associated with reduced risk of death

APOE gene: A major driver in Alzheimer's disease

Stopping weight loss drugs leads to rapid weight regain and health reversal

Experimental drug targets early toxic amyloid to slow Alzheimer’s disease

High fructose intake increases fatty liver risk

What happens to your body when you eat takeaway food too often?

Family history of cardiometabolic disease linked to early heart damage in adolescents

Recurrent strokes can be avoided with optimal prevention and follow-up

CAR T cell therapy could be a highly effective tool against atherosclerosis

Current genetic screening guidelines overlook most cases of familial hypercholesterolemia

Income and social disparities found to influence dementia risk factors

New data supports earlier use of evolocumab in high-risk diabetes

New initiative boosts cholesterol control in veterans with heart and blood vessel disease

One-time CRISPR therapy safely lowers cholesterol and triglycerides in early trial

PCSK9 inhibitor combined with a statin may help reduce LDL cholesterol after heart transplant

Exploring cost-effective approaches to detecting familial hypercholesterolemia in children

People with traumatic spinal cord injuries at higher risk of developing chronic health problems

First-of-its-kind resource created to identify people with genetic risk for elevated 'bad' cholesterol

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