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Potential new mRNA-based therapy for pre-eclampsia

Lipid nanoparticles targeting VEGF mRNA show promise in treating pre-eclampsia, restoring maternal blood pressure and enhancing fetal health in murine models.

13 Dec 2024

DTI detects precancerous lesions in the pancreas

Precursor lesions of pancreatic cancer are very difficult to characterize with magnetic resonance imaging (MRI). But now, in a new study, researchers led by Noam Shemesh and Carlos Bilreiro – respectively head of the Preclinical MRI lab at Champalimaud Research and a doctor at the Champalimaud Clinical Centre's Radiology Department – have shown, for the first time, that a particular form of MRI, called Diffusion Tensor Imaging (DTI), is capable of robustly detecting pre-malignant lesions in the pancreas.

13 Dec 2024

Chest wall irradiation does not impact 10-year survival in intermediate-risk breast cancer

Patients with intermediate-risk breast cancer had similar rates of 10-year overall survival whether or not they underwent chest wall irradiation (CWI) after mastectomy, according to results from the BIG 2-04 MRC SUPREMO clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.

12 Dec 2024

Two new subtypes of MASH revealed with different risks and outcomes

Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly referred to as nonalcoholic fatty liver disease (NAFLD), impacts roughly 30% of the global adult population.

9 Dec 2024

Aging reduces cancer risk by limiting cell regeneration

When it comes to cancer, aging is a double-edged sword, researchers are increasingly learning.

4 Dec 2024

Scientists decode ovarian aging with groundbreaking molecular atlas

Researchers unveil a comprehensive multi-omics atlas of ovarian aging, highlighting coordinated gene expression changes, mTOR signaling, and cellular communication as key to understanding fertility decline.

26 Nov 2024

BiomedParse transforms biomedical image analysis with groundbreaking precision and scalability

BiomedParse, a revolutionary biomedical model, unifies image segmentation, detection, and recognition across nine modalities, outperforming traditional methods and enabling scalable, precise analysis of complex biomedical images.

21 Nov 2024

Researchers reveal cellular foundations of functional brain networks in humans

Rutgers researchers at the Brain Health Institute (BHI) and Center for Advanced Human Brain Imaging Research (CAHBIR) have uncovered how different types of brain cells work together to form large-scale functional networks in the human brain – interconnected systems that support everything from sensory processing to complex decision-making – paving the way for new insights into brain health and disease.

21 Nov 2024

AI technique helps neurosurgeons detect hidden cancer during brain tumor surgery

Technique offers new hope for increased survival in patients with brain tumors.

13 Nov 2024

Traditional and cutting-edge endoscopic modalities in colorectal cancer diagnosis

The evolution of gastrointestinal (GI) endoscopy has transformed CRC diagnostics since its early 20th-century origins.

8 Nov 2024

Taurine supplementation linked to reduced atherosclerotic plaque development

Previous studies suggest that taurine supplementation may attenuate atherosclerosis by reducing lipid levels. However, energy drinks containing taurine have been shown to increase blood pressure, a key risk factor for atherosclerosis. Thus, the role of taurine in atherosclerosis remains controversial.

26 Oct 2024

New plasma treatment shows promise for healing rotator cuff injuries

The human body, filled with muscles and moving parts, is far from indestructible. Injuries are common, especially where tendons and bones connect.

25 Oct 2024

FDA-approved breast cancer drug shows promise for appendix cancer

Researchers at University of California San Diego School of Medicine found an FDA-approved drug used to treat breast cancer has the potential to be an effective therapeutic for a specific type of appendix cancer.

16 Oct 2024

Patient-derived gut organoids reveal new insights into Crohn's disease subtypes

Crohn's disease - an autoimmune disorder - is characterized by chronic inflammation of the digestive tract, resulting in a slew of debilitating gastrointestinal symptoms that vary from patient to patient.

26 Sep 2024

New pipeline of drug candidates offers hope for effective MASLD treatments

Non-alcoholic fatty liver disease (NAFLD), recently reclassified as metabolic dysfunction-associated steatotic liver disease (MASLD), has become the most prevalent chronic liver disease globally.

25 Sep 2024

AI tool enhances cancer diagnosis by transforming standard tissue images

VirtualMultiplexer transforms histology images into detailed cancer markers, streamlining diagnostics and enhancing patient outcomes through AI innovation.

12 Sep 2024

Brazilian research uncovers how liver nerves regulate glucose production under stress

A study led by Brazilian researchers has produced a detailed description of the morphology of the nerves in the liver and how they control production of glucose when the organism is under stress.

11 Sep 2024

Early cholesterol spikes fuel atherosclerosis by altering macrophages

Early intermittent hyperlipidemia significantly accelerates atherosclerosis by disrupting macrophage function, highlighting the need for early cholesterol management.

6 Sep 2024

Can how often you eat meat raise your risk of colorectal cancer?

Study shows that high processed meat intake significantly increases colorectal neoplasm risk, with effects equivalent to a 19 percentile increase in genetic risk scores, while red meat consumption shows no significant association.

11 Aug 2024