Immune System News and Research

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Women with autoimmune diseases more likely to receive psychiatric misdiagnoses

Females with autoimmune diseases are significantly more likely than males to have their autoimmune disease misdiagnosed as a psychiatric or psychosomatic condition, according to a study of more than 6,600 patients.

12 Oct 2026

Review highlights EP4 receptor as target for inflammatory diseases

A review published in Genes & Diseases highlights the prostaglandin E2 receptor subtype 4 (EP4) as an important regulator of inflammation and a promising therapeutic target for a wide range of inflammatory and inflammation-related diseases.

12 Oct 2026

Blood proteins may offer new clues to gut health in celiac disease

Celiac disease is an autoimmune condition in which the immune system reacts adversely to gluten. Eating gluten causes inflammation in the gut, which can damage the intestine and impair its ability to absorb nutrients.

10 Oct 2026

New signaling pathway enhances blood stem cell transplantation outcomes

Gene therapies are used to treat many different blood disorders. However, blood stem cells often fail to achieve their full potential after transplantation.

9 Oct 2026

New immune aging map helps decode future chronic disease risks

While birthday candles measure the number of years someone has lived, they don't always tell the full story about someone's health.

9 Oct 2026

Study explains why cancer immunity declines faster in males

Lutz Menzel, PhD, formerly of the Department of Radiation Oncology within the Mass General Brigham Cancer Institute, and Tim Padera, PhD, currently of the Mass General Brigham Cancer Institute, are the lead and senior authors of a paper published in Nature Aging, "Lymph node contraction links sex-biased naive CD8 T cell decline to compromised antigen recognition during middle age."

9 Oct 2026

New research unveils role of innate immune system in pancreatic cancer

Researchers from Adelaide University have demonstrated that blocking a specific immune system gene can reduce pancreatic cancer tumor formation.

9 Oct 2026

$13.1 million grant backs bacterial therapies for resistant breast cancer

A scientist at Weill Cornell Medicine is working with colleagues at the University of Massachusetts Amherst on new, complementary research efforts engineering therapeutic Salmonella to target critical gaps in treatment for drug-resistant triple-negative breast cancers.

9 Oct 2026

Rare dendritic cells may promote immune tolerance in metastatic cancer

This study was co-led by Steven Blum, MD. Gary Reynolds, MD, PhD, Samuel Klempner, MD, and Alexandra-Chloé Villani, PhD, jointly supervised the work at the Krantz Family Center for Cancer Research within the Mass General Brigham Cancer Institute and the Mass General Brigham Center for Immunology & Inflammatory Diseases (CIID).

8 Oct 2026

Blood biomarkers help track gut pathology in celiac disease

8 Oct 2026

Excess adiposity may alter the immune environment of airways to promote lung cancer

In a recent study of more than a thousand individuals, greater adiposity, or excessive body fat or fatty tissue, specifically in the abdomen, was associated with lung cancer.

8 Oct 2026

Combination therapy overcomes immunotherapy resistance in glioblastoma

Scientists at The Wistar Institute have identified a combination treatment that overcomes two of the biggest barriers to immunotherapy in glioblastoma.

8 Oct 2026

New SPARCS technology combines AI and microscopy to screen cells

New technology combines artificial intelligence and microscopy to screen cells at large scale.

8 Oct 2026

Vaccination protects the immune system from long-term infection damage

Vaccination not only prevents disease caused by acute infection but also protects against long-term immune-related sequelae that can follow an acute viral infection.

8 Oct 2026

Hydroxyurea does not increase infection risk in children with sickle cell anemia

Children living with sickle cell anemia have no higher incidence of clinically diagnosed infections when treated with hydroxyurea.

8 Oct 2026

Researchers find gene expression patterns linked to severe pediatric COVID-19

Researchers have identified patterns of gene activity associated with severe COVID-19 in children that are shared with other serious respiratory infections.

7 Oct 2026

Global scientific collaboration brings hope to lobular breast cancer patients

Every October, Breast Cancer Awareness Month brings people around the world together under the pink ribbon to raise awareness, encourage early detection, support patients and fund research.

6 Oct 2026

New AI model detects heart transplant rejection without biopsies

By analyzing heart rhythm recordings and blood tests, artificial intelligence may accurately flag when a transplant patient's body starts attacking a donated heart, a new study suggests.

6 Oct 2026

Scientists discover a novel strategy to unmask cancer cells in high-risk neuroblastoma

High-risk neuroblastoma is one of the most aggressive forms of solid tumors affecting children, originating in the nervous system.

6 Oct 2026

SGLT2 inhibitors reduce inflammatory cells linked to heart disease

For the first time in a human trial, a class of drugs known as sodium-glucose cotransporter-2 (SGLT2) inhibitors, already known for their weight loss and glucose lowering benefits, has been shown to also reduce inflammatory cells in the blood known to cause cardiovascular disease.

6 Oct 2026