Immunodeficiency News and Research

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Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

COVID-19 vaccines may cut risk of long COVID

Full COVID-19 vaccination may reduce post-COVID-19 condition risk by 27%, though more research is needed, especially for children and immunocompromised groups.

26 Mar 2025

Anti-HIV active diterpenoids identified in Daphne pseudomezereum

A research group led by Professor Wei Li from the Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Toho University, in collaboration with the Duke University Medical Center in the United States, has discovered for the first time that Daphne pseudomezereum (commonly known as Onishibari) contains a substance inhibiting replication of human immunodeficiency virus (HIV).

21 Mar 2025

Breakthrough peptide inhibitor effective against multiple SARS-CoV-2 variants

SARS-CoV-2, the virus responsible for COVID-19, infects cells by binding its spike protein to angiotensin-converting enzyme 2 (ACE2) receptors.

14 Mar 2025

Gut microbiota impacts pneumococcal vaccine response in immunodeficient individuals

Gut microbiota may be the key factor explaining why certain individuals do not respond well to the pneumococcal vaccine-a bacterium that can cause various diseases, such as pneumonia.

13 Mar 2025

FDA ensures blood safety through five layers of safeguards

Every day, hospitals throughout the U.S. transfuse blood or blood components, such as platelets, to save the lives of people who are in car crashes, and victims of fires and other emergencies.

20 Feb 2025

The growing list of human viruses: Are we prepared for the next outbreak?

Researchers review the ever-growing list of human viruses, examining their diversity, transmission pathways, and the urgent need for prevention and global surveillance.

12 Feb 2025

Urban density and HIV prevalence linked to rising antibiotic resistance in gonorrhea

Researchers identify key geographic and health factors that may predict the prevalence of antimicrobial-resistant gonorrhea in the United States.

7 Feb 2025

New study confirms CAR T cell therapy does not cause secondary cancers

Within a large group of more than 700 patients treated with CAR T cell therapy, researchers found no evidence that the therapy itself caused any type of secondary cancer in the modified T cells, according to new analysis reported today in Nature Medicine from the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine's Abramson Cancer Center.

3 Feb 2025

The impact of extreme weather events on HIV prevention and care

Researchers review the impact of extreme weather events related to climate change on HIV strategies.

13 Jan 2025

Complex interactions between nucleic acid sensors and enzymes in immune cells explained

Adenosine deaminase 2 (ADA2) has been identified as a regulator of toll-like receptor 9 (TLR9) activation in response to nucleic acids, according to a recent study.

26 Dec 2024

Breastfeeding after COVID-19 vaccination is safe, with minimal changes to milk composition

This study reveals how SARS-CoV-2 infection significantly alters human milk composition, while COVID-19 vaccination causes minimal, transient changes, underscoring the safety of breastfeeding during vaccination.

19 Dec 2024

Researchers discover weakness in bacterial machinery that drives antibiotic resistance

Superbugs, bacteria that are immune to multiple antibiotics, pose a great challenge to modern medicine. Researchers from the B CUBE - Center for Molecular Bioengineering at TUD Dresden University of Technology and Institut Pasteur in Paris identified a weakness in the bacterial machinery that drives antibiotic resistance adaptation.

17 Dec 2024

PD-1 deficiency reveals the impact of checkpoint inhibition on B cell function

A multinational collaboration co-led by the Garvan Institute of Medical Research has uncovered a potential explanation for why some cancer patients receiving a type of immunotherapy called checkpoint inhibitors experience increased susceptibility to common infections.

27 Nov 2024

Growing gulf in US life expectancy deepened by COVID-19 pandemic

Researchers update their analysis from the original Eight Americas study to reflect current life expectancy disparities in the United States.

26 Nov 2024

WHO grants Emergency Use Listing for LC16m8 mpox vaccine

The World Health Organization (WHO) has granted Emergency Use Listing (EUL) for the LC16m8 mpox vaccine, making it the second mpox vaccine to be supported by WHO following the Director-General's declaration of an mpox public health emergency of international concern (PHEIC) on 14 August 2024.

19 Nov 2024